Imaging the hidden player: Choroid plexus enlargement in multiple sclerosis

The choroid plexus (CP), one key regulator of cerebrospinal fluid (CSF) production and immune surveillance at the blood–CSF barrier, has recently emer…

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Therapeutic approaches in adults with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): A review of current evidence

Recent years have seen a considerable increase in knowledge pertaining to Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD). Nev…

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Cortical Single-Cell Primers of Abnormal Brain Activity in Parkinson’s Disease | Research

Abnormal brain oscillatory activity is a well-established hallmark of bradykinesia and motor impairment in Parkinson’s disease (PD), yet its molecular underpinnings remain unclear. To address this gap...

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Frequency- and layer-specific effects of high-frequency STN stimulation on mouse motor cortical areas in vivo

Abstract. High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective evidence-based therapy for Parkinson’s disease; howe

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Structural covariance analysis for neurodegenerative and neuroinflammatory brain disorders

Standard MRI focuses on brain structure but may not fully capture disease progression. Mongay-Ochoa et al. review advanced methods for mapping brain connec

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Extended coverage of human serum glycosphingolipidome by 4D-RP-LC TIMS-PASEF unravels association with Parkinson’s disease - Nature Communications

4D-TIMS-glycosphingolipidomics expedite clinical serum profiling of 376 GSLs covering ganglio- and neolacto-series, neutrals and sulfatides. Clinical phenotyping of Parkinson’s disease cohort (sub)gro...

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Targeting pathological brain activity-related to neuroinflammation through scRNA-seq for new personalized therapies in Parkinson’s disease - Signal Transduction and Targeted Therapy

Signal Transduction and Targeted Therapy - Targeting pathological brain activity-related to neuroinflammation through scRNA-seq for new personalized therapies in Parkinson’s disease

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Low‐Frequency Deep Brain Stimulation in Non‐Rapid Eye Movement Sleep Modifies Memory Retention in Parkinson's Disease

Background and Objective Memory impairment is a frequent and debilitating symptom in neurodegenerative disorders. The objective of this study was to provide proof-of-principle that deep brain stimul...

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Subthalamic control of impulsive actions: insights from deep brain stimulation in Parkinson’s disease

Herz et al. review recent studies that have used deep brain stimulation electrodes to record neural activity from, or apply electrical stimulation to, the

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Translational Methods for Parkinson’s Disease and Atypical Parkinsonism Research

This volume covers translational paths used to study the pathophysiology of Parkinson’s Disease such as molecular processes and tissue integrity.

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Inflammation‐Triggered Enlargement of Choroid Plexus in Subacute COVID‐19 Patients with Neurological Symptoms

<em>Annals of Neurology</em> is a leading neurology journal from the American Neurological Association focusing on diseases of the human nervous system.

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Concurrent inflammation-related brain reorganization in multiple sclerosis and depression

Neuroinflammation affects brain tissue integrity in multiple sclerosis (MS) and may have a role in major depressive disorder (MDD). Whether advanced m…

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Advanced therapies in Parkinson’s disease: an individualized approach to their indication - Journal of Neural Transmission

Device aided therapies (DAT) comprising the intrajejunal administration of levodopa/carbidopa intestinal gel (LCIG) and levodopa/carbidopa/entacapone intestinal gel (LECIG), the continuous subcutaneou...

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Subthalamic stimulation modulates context-dependent effects of beta bursts during fine motor control - Nature Communications

How movement speed is neurally modulated remains poorly understood. Here, the authors recorded invasive brain signals in Parkinson’s disease patients during drawing and deep brain stimulation, showing...

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Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories

Three discrete immunological endophenotypes in early multiple sclerosis correlate with distinct disease trajectories and treatment responses.

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Cerebral vasculitis as a clinical manifestation of neurosarcoidosis: A scoping review

The occurrence of cerebral vasculitis in individuals with neurosarcoidosis (NS) is considered to be rare. Although the number of relevant publications…

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Ultrafast Brain MRI with Deep Learning Reconstruction for Suspected Acute Ischemic Stroke

Background Deep learning (DL)–accelerated MRI can substantially reduce examination times. However, studies prospectively evaluating the diagnostic performance of DL-accelerated MRI reconstructions in ...

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