Seong-won Han
@seongwonhan.bsky.social
Postdoc at UofArizona. Muscle mechanist & physiologist. Obsessed with titin and its role in muscle contraction. #Biomech
So great to see our recent publication featured in the Research News @jgp.org! 💪🔬 #Titin #Muscle #Biomech
Journal of General Physiology@jgp.org · last yr.New study (@seongwonhan.bsky.social et al doi.org/10.1085/jgp....) reveals that glycerol storage increases the titin-based stiffness of muscle fibers, suggesting that this commonly used method should be avoided by researchers interested in the passive properties of muscle rupress.org/jgp/article/...
[🚨New paper alert!] If you store muscle tissue in glycerol-mixed solution for long-term preservation, check out our new paper published in @jgp.org. Glycerol storage significantly elevates passive stiffness of muscle fibers in a titin-specific manner! More details are: rupress.org/jgp/article/...
Glycerol storage increases passive stiffness of muscle fibers through effects on titin extensibility | Journal of General Physiology | Rockefeller University Press
To store and preserve muscle function, glycerol is often used, but its effect on passive properties is unclear. Muscles stored in glycerol showed increased
rupress.org
📢Another single myofibrillar work just published at @jbiomech.bsky.social! We found single cardiac myofibrils exhibit residual force depression after active shortening, similar to what's been found in skeletal muscle. Want more details? Check it out below! www.sciencedirect.com/science/arti...
Residual force depression in cardiac myofibrils
History-dependent properties, such as residual force depression (rFD; i.e., the decrease in steady-state isometric force of a muscle, following active…
sciencedirect.com
Paper alert!📢 We systematically explored the nature of sarcomere length non-uniformity using single myofibrils, and found that sarcomere length non-uniformity does NOT occur randomly in both active and passive states! Details can be found: 👇 www.frontiersin.org/articles/10.... #BiomechSky
Gaining new understanding of sarcomere length non-uniformities in skeletal muscles
Sarcomere lengths are non-uniform on all structural levels of mammalian skeletal muscle. These nonuniformities have been associated with a variety of mechanical properties, including residual force en...
frontiersin.org
There are some fantastic TT job opportunities for biomechanics and neuromechanics (human and comparative). A few of them: Brown; biomch-l.isbweb.org/forum/biomch... SFU; csb-scb.com/tenure-track... Umass: careers.umass.edu/en-us/job/52... twitter.com/SarahRoelker... 1/2 #BiomechSky
Faculty position at Brown University in Organismal Biology (including biomechanics and anatom...
Assistant Professor in Organismal Biology The Department of Ecology, Evolution, and Organismal Biology (EEOB) at Brown University seeks to fill a tenure track, Assistant Professor position for a broa...
biomch-l.isbweb.org
A few more: Stanford: facultypositions.stanford.edu/en-us/job/49... Berkeley: aprecruit.berkeley.edu/JPF04087 Oregon: careers.uoregon.edu/en-us/job/53... 2/2 #BiomechSky
Stanford | Faculty Positions: Details - Assistant Professor in Animal Physiology
facultypositions.stanford.edu
Image that makes me excited every time I see - single myofibrils labelled with fluorescent dyes. Trying to capture videos to see how these labels move during passive/active lengthening and shortening! #BiomechSky
