Tessera
Folgen

Seth Masters

@sethlucianmasters.bsky.social

Professor and Head of the Centre for Innate Immunity and Infectious Disease at the Hudson Institute.

11 Posts1365 Follower377 Folgt
Seth Masters@sethlucianmasters.bsky.social · last yr.

A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with genetic variants in NLRP3. Lots of "variants of uncertain significance" now have a specific readout from our in vitro assay which can help with clinical diagnosis. rdcu.be/d9iRG

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants

Nature Immunology - Gain-of-function variants in the gene encoding NLRP3 lead to constitutive inflammasome activation and excessive IL-1β production. In this resource, authors perform...

rdcu.be

Seth Masters@sethlucianmasters.bsky.social · 2y ago

The 3rd Australian #autoinflammatory Disease Symposium will be combined with an Education Summit on Paediatric Rheumatology, in partnership with Zoe’s Angels: 21-22 Feb 2025 in Brisbane! imb.uq.edu.au/event/20941/...

3rd Autoinflammatory Disease Symposium & Education Summit on Paediatric Rheumatology

Following previous meetings in 2017 (Garvan Institute) and 2022 (WEHI), the 3rd Autoinflammatory Disease Symposium will be combined with an Education Summit on Paediatric Rheumatology, in partnership ...

imb.uq.edu.au