🚨🦠 Reviews are in for a study reporting that human interferon-stimulated genes can restrict bacteriophage replication, highlighting conserved antiviral mechanisms across bacteria and humans. rrid.mitpress.mit.edu/pub/s2c5kn9i...

Reviews of: "Human Interferon Stimulated Genes Target Ancient Features of Animal and Bacterial Viral Replication"

Reviewers: J MacMicking (HHMI, Yale University) & S Silverman (Yale University) & K V Narvaez (Yale University) | 📗📗📗📗◻️ • T Nagy (University of Colorado Boulder) | 📗📗📗📗◻️ • J Pogliano (UC San Diego...

rrid.mitpress.mit.edu

Congrats to @courtneyrsantos.bsky.social and @kvnforsberg.bsky.social on a lovely story!

Kevin Forsberg@kvnforsberg.bsky.social · 2mo ago

Humans and bacteria share strategies to defend against viruses. We wondered: could they use each other's genes? Yes, both can! Bacteria can use human immune genes to defend against phages AND Human cells can use bacterial genes for viral defense. www.biorxiv.org/content/10.6...

How do human cells defend against viruses? @sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics www.biorxiv.org/content/10.6...