Rasmus Siersbaek

@siersbaek.bsky.social

Molecular cancer biologist fascinated by gene regulation, chromatin and epigenetics. Based in Denmark.

Nucleosome fibre topology guides transcription factor binding to enhancers www.nature.com/articles/s41... ▶️motif recognition on mononucleosomes affects only an individual TF binding ▶️When bound together, TFs act cooperatively or competitively to target nucleosome arrays with defined 3D organization

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