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SLEEP and SLEEP Advances

@sleepjournals.bsky.social

Official journals of the Sleep Research Society and the Australasian Sleep Association.

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 8h ago

When you're sick, you often suffer from #sleepiness and excessive fatigue, making healing that much more difficult. Researchers believe that tricyclic #antidepressants could potentially lessen the effects of sickness-induced fatigue. This drug panel was tested in #C.elegans models.

Tricyclic antidepressants suppress sleep in Caenorhabditis elegans

AbstractStudy Objectives. Sleepiness and fatigue are common symptoms during illness and may persist after the resolution of illness. To gain insight into t

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · yesterday

In adolescents, sleep problems are associated with #depression and suicidal ideations. However, the contributing factors for this relationship is unknown. Using the Millennium Cohort Study (MCS), researchers analyzed the mediating effect of depression on sleep problems and suicidal thoughts.

Sleep problems, decision-making, and suicide attempts during adolescence: a longitudinal birth cohort study

AbstractStudy Objectives. Sleep problems have been identified as a risk factor for suicidal thoughts and behaviors during adolescence, yet a lack of longit

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2d ago

Non-Rapid Eye Movement (NREM) sleep power spectrum is believed to hold rhythms responsible for sleep-dependent #memoryconsolidation. These #NREM sleep oscillations are affected during aging. in this study, researchers observed the mediation of age on these oscillations in #micemodels.

Rhythmic and arrhythmic components from local-field potentials during non-rapid eye movement sleep in younger and older mice

Abstract. The non-rapid-eye movement (NREM) sleep power spectrum is composed of rhythmic and arrhythmic components, respectively associated with brain rhyt

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 5d ago

During #REM sleep, sublaterodorsal tegmental nucleus (SLD) glutamate neurons cause skeletal muscle paralysis and cortical activation. In this study, researchers work to characterize brain-wide #glutamatergicinputs to the SLD. Mice models are employed for genetically-assisted tract tracing.

Identification of glutamatergic inputs to the sublaterodorsal tegmental nucleus and their role in rapid eye movement sleep control

Abstract. Rapid eye movement (REM) sleep is characterized by rapid eye movements, cortical activation, and paralysis of skeletal muscles. Sublaterodorsal t

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 6d ago

The #SleepWakeCycle is regulated by the #CerebralAdenosinergicSystem. During #AcuteSleepDeprivation, #CerebralA1AdenosineReceptor availability increases, contributing to #CognitiveImpairment. This study used #Polysomnography, #PET, and cognitive testing to examine #ChronicSleepDeprivation.

Chronic sleep loss and A1 adenosine receptors in the human brain

AbstractStudy Objectives. The cerebral adenosinergic system is involved in sleep–wake regulation and presumably represents a neuro-molecular correlate of h

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last wk.

#Sensoryinputgating allows for infants to block out their environment to initiate and maintain sleep. Children with #autism often struggle with this #neuronalprocess leading to #sleepdifficulties. 44 infants were monitored to better observe #sensoryreactivity in #quiet and #noisy sleep environments.

Sound asleep: sensory decoupling during sleep depends on an infant’s sensory profile

Abstract. Initiating and maintaining sleep requires gating of sensory input. Sensory processing differences, such as elevated sensory reactivity, have emer

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last wk.

Researchers analyze #sleephealthimprovements in a Catalonian cohort following the #COVID19pandemic. Using the #SATED and #RUSATED questionnaires, researchers saw marked improvement and stabilization of #sleephealth following the #COVIDpandemic.

Sleep health improvement trajectories after a pandemic: insights from a national health survey

Statement of Significance This study offers new insights into how sleep health changed in the general population following the COVID-19 pandemic. By analyz

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2w ago

The #PROK2 peptide has been studied in the adult brain for its #neuroprotective role and analyzed in regard to #Parkinson'sDisease. In this study, researchers investigate its involvement in #idiopathicREMBehaviorDisorder (iRBD), along with #PROK2receptors in search of an a-synucelopathic #biomarker.

The Prokineticin system is downregulated in idiopathic rapid eye movement sleep behavior disorder: evidence from olfactory neurons

AbstractStudy Objectives. PROK2 is a peptide expressed in the adult brain mediating neuroprotective functions. Previous studies reported an upregulation of

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2w ago

📣 Join the SLEEP Advances Editorial Advisory Board SLEEP Advances is expanding our Editorial Advisory Board. Qualifications include: ✅ Master's, PhD, or MD degree ✅ Active in sleep or circadian research ✅ Previous experience with peer review If interested, complete our brief form below:

SLEEP Advances Editorial Advisory Board Interest

Please complete this form to express interest in joining the Editorial Advisory Board of SLEEP Advances

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2w ago

Individuals that have had #COVID have had #poorsleepoutcomes; however, the relationship been #SARSCOV2 and its impact on #sleephealth is not well understood. In this study, researchers analyzed sleep of individuals on #MilitaryHealthServices with #SARSCOV2 infection.

SARS-CoV-2 infection and sleep health in Military Health System beneficiaries

AbstractStudy Objectives. The relationship between Coronavirus disease 2019 (COVID-19) and sleep health is unclear; therefore, we examined the association

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2w ago

Brain #pericytes control #cerebralbloodflow or #neurovascularcoupling in response to brain activity. Neurovascular coupling during #sleepcycle and #wakecycles is not well understood. In this study, researchers employed #in-vivo #calciumimaging to better understand #pericyte activity.

Region-specific pericyte Ca2+ transient dynamics and capillary hemodynamics during the sleep–wake cycle

Statement of Significance This study examines the activity dynamics of brain capillary pericytes, the mural cells contributing to cerebral blood flow (CBF)

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2w ago

#Alcoholconsumption has been shown to have adverse effects on #restorativesleep and induce #memoryloss or #blackouts with equally adverse effects on #sleephealth. In this study, researchers assess #priornightsleep as a predictor of blackouts after #alcohol consumption. @jenmerrillphd.bsky.social

Prior-night sleep as an event-level predictor of alcohol-induced memory loss

Statement of Significance This study demonstrates that poor sleep health the night before drinking alcohol increases risk for alcohol-induced memory loss.

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2w ago

This author advocates the importance of #thescienceofsleep and how best to study it. The field of #sleepscience has focused primarily on understanding #sleepfunction and #sleepneuralmechanisms. The author advocates for more research on #sleepdevelopment across time and species.

The undeniable value of developmental analysis for the science of sleep

To understand sleep, we must understand how it develops. In a field that has largely relegated development to a secondary role, this claim may strike many

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 3w ago

#isolatedREMSleepBehaviorDisorder (iRBD) is a diagnosis that has been relatively understudied in terms of #clinicalpathology. In this study, #basalelectromyographic (EMG) amplitude during sleep to better understand #sleepcyclechanges in comparison to those without #iRBD.

Basal electromyographic amplitude in rapid eye movement (REM) and non-rapid eye movement (NREM) sleep as a predictor of disease progression in isolated REM sleep behavior disorder

AbstractStudy Objectives. This study examined whether basal electromyographic (EMG) amplitude during sleep is altered in patients with isolated REM sleep b

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 3w ago

#Sleephealth and the #circadianrhythm impact #metabolism, especially in regards to #glucosehomeostasis. In this paper, researchers worked to understand the negative affect #sleeprestriction can have on #glucosemetabolism as well as the mediating effects #sleeprecovery and #sleepduration.

Glucose homeostasis during recurrent periods of sleep restriction and recovery in healthy young adults

AbstractStudy Objectives. To investigate if glucose homeostasis was impaired during recurrent periods of sleep restriction and recovery, and if the impairm

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 3w ago

Alterations in #sleep-wakepatterns during #REMsleep is characteristic to #isolatedREMSleepBehaviorDisorder (iRBD). For this study, researchers collected #ambulatory #circadianrhythmdata to better understand #sleepstage distinctions in adults with and without #iRBD.

Circadian alterations in isolated Rapid-Eye-Movement sleep behavior disorder: associations with clinical, glymphatic, and dopaminergic imaging markers

Statement of Significance This study identifies circadian rhythm disturbances as a core feature of isolated REM sleep behavior disorder, a prodromal phase

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 3w ago

Many individuals diagnosed with #insomnia also experience #alcoholmisuse. #CognitiveBehavioralTherapyforInsomnia (CBT-I) has yet to be studied in treating #alcoholdependence. In this study, researchers developed a pilot #CBT-I program for those with #insomnia and #hazaradousalcoholuse (HAU).

Cognitive behavioral therapy for insomnia modified for adults with hazardous alcohol use: an open-label pilot study

AbstractStudy Objectives. Insomnia is highly prevalent and frequently comorbid with alcohol misuse. Cognitive behavioral therapy for insomnia (CBTi), the f

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last mo.

#ObstructiveSleepApnea (OSA) has been extensively studied for its impacts on #sleephealth and #cardiometabolichealth as a result. In this study, researchers implicate #OSA in #neurodegeneration in a study of the Pomerania cohort's #generalpopulation.

The longitudinal effect of sleep apnea on changes in brain structure in a population-based sample

AbstractStudy Objectives. Increasing evidence points towards sleep apnea as a modifiable risk factor for neurodegeneration. This study investigates the lon

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last mo.

#Twiches during #REMsleep are a common phenomenon for all ages. In three-month-olds, this twitching also happens in #NREMsleep. In this study, they studied twitching differences between #NREM2 and #NREM3sleep to better understand #sensorimotordevelopment in infants. @marksblumberg.bsky.social

Does twitch-spindle coupling differ between N2 and N3 sleep in 6-month-olds?

Statement of Significance Twitching has long been recognized as a core component of mammalian rapid eye movement (REM) sleep. However, twitching also occur

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last mo.

#REMsleep is especially important for building #physiologicalresilience when experiencing emotional events. In clinical settings, fragmented #REMsleep has shown to cause #maladaptiveemotionalprocessing. The #emotionalmemory of healthy participants was analyzed, mirroring these same clinical trends.

Experimentally induced REM sleep fragmentation affects psychophysiological habituation to emotional stimuli

Abstract. Rapid eye movement sleep is believed to reduce physiological reactivity to emotional experiences. While rapid eye movement sleep fragmentation ha

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last mo.

New information about #sleepcharacteristics in different populations is still being uncovered. This article discusses #agedifferences and #sexdifferences in self-reported #sleep and #mood. academic.oup.com/sleepadvance...

Age- and sex-related differences in sleep patterns and their relations to self-reported sleep and mood

Abstract. Sleep is a fundamental biological process associated with diverse physiological and psychological functions, yet systematic, population-level, ob

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last mo.

#CogntiveBehavioralTherapy (CBT-I) remains a popular part of treatment for #insomnia. Changes to #CBT-I have been made to address fear of sleep in those with #PTSD following #CognitiveProcessingTherapy. academic.oup.com/sleepadvance...

Adaptations to cognitive behavioral therapy for insomnia to address fear of sleep and its sequential impact on posttraumatic stress disorder following cognitive processing therapy

Posttraumatic stress disorder (PTSD) is associated with a range of comorbidities, including cardiovascular health, immune function, depression, suicide, an

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last mo.

A new to-do initiative explores diagnosis of #sleep-related #circadiandisorders. The #aviation industry 🛫requires its pilots to have great #sleep health and #alertness for each shift. This #review article analyzes the use of #consumer sleep technologies amongst the field.

A narrative review on in-flight use of consumer sleep technologies for aviation research

Abstract. Aviation is a global safety-sensitive industry that employs strict guidance about the monitoring and management of fatigue. Ecological sleep data

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · last mo.

The impact of serum #VitaminC on #sleepmeasures was investigated in healthy #adults as well as #melatoninlevels. academic.oup.com/sleepadvance...

Serum 25-hydroxyvitamin D concentration is associated with device-estimated sleep metrics in healthy young and early middle-aged adults

Statement of Significance Here, we utilize 14 days of wrist actigraphy to evaluate cross-sectional associations between serum 25-hydroxyvitamin D ([25(OH)D

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SLEEP and SLEEP Advances@sleepjournals.bsky.social · 2mo ago

The #glymphaticsystem helps by flushing plaque from the #brain. Older adults can have issues with #glymphaticdrainage due to low electrical current in the #extracellularspace (ECS). Researchers applied #transcranialelectronicstimulation (tES) to enhance #N3sleep and improve #glymphaticdrainage.

tES synchronization of slow oscillations in N3 sleep decreases brain electrical impedance: implications for improved brain waste clearance

Abstract. The age-related impairment of glial-lymph (glymphatic) mechanisms for brain waste clearance has been suspected as a causal factor in the accumula

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