Society for Mucosal Immunology
@societymucosalimm.bsky.social
https://www.socmucimm.org/ Advancing research, education, and collaboration in the field of mucosal immunology since 1987.
Control of M. tuberculosis infection requires CD28 to generate lung-homing T cells and CTLA-4 to limit immunopathology from @danbarberphd.bsky.social @nelson-lab.bsky.social @uvaresearch.bsky.social @uvaimmunology.bsky.social: www.mucosalimmunology.org/article/S193...
It’s #MucosalMonday and time for a fresh Mucosal Immunology Podcast Episode. Hear from @emeshlem.bsky.social, @alenghatlab.bsky.social and more! www.iheart.com/podcast/269-...
Inflammasome Signaling in the Intestine - Mucosal Immunology Podcast | iHeart
<p>Drs. Emily Eshleman, and Theresa Alenghat are in the Author’s Corner with Kathryn Knoop to discuss their work: <a href='https://www.mucosalimmunology.org/article/S1933-0219(26)00058-9/fulltex...
iheart.com
Please join us in celebrating: -Per Brandtzaeg Distinguished Scientific Achievement Award - Richard K. Grencis, PhD -Distinguished Service Award - Kathryn Knoop, PhD -Brian Kelsall Medal - Nadine Cerf-Brensussan, MD, PhD -Young Investigator Award - Reinhard Hinterleitner, PhD & Lars Vereecke, PhD
Read the latest #SMIMemberPaper by Jan Niess and colleagues in @J_Immunol on how the risk gene Rgs14 is involved in #IBD. Deletion in macrophages changes their ROS production and inducing T cell proliferation. Read more here: academic.oup.com/jimmunol/art...
Validate User
academic.oup.com
Read the latest #SMIMemberPaper by @thehandiestlab and colleagues in @cellhostmicrobe on their novel technique to identify microbes bound by immunoglobulins by combining bacteria specific fluorescent probes with spectral flow for absolute quantification and tracking in preterm infants. Read more:
sciencedirect.com
Read the latest #SMIMemberPaper by Ludvig Sollid and colleagues in @PNASNews on how in #Celiac the HLA affects disease risk by selection of a disease-relevant TCR repertoire in naïve CD4 T cells. Read more here: www.pnas.org/doi/10.1073/...
A predisposing effect of HLA class II genes in celiac disease by skewing the naive CD4+ T cell receptor repertoire | PNAS
Polymorphisms of human leukocyte antigen (HLA) genes confer risks for human diseases. Predisposing effects related to T cell receptor (TCR) recogni...
pnas.org
MHC class II antigen presentation (visualized in red) by intestinal epithelial cells (visualized in the blue and white staining of the organoid) fine-tunes bacteria-reactive CD4 T-cell responses www.mucosalimmunology.org/article/S193...
Mucosal-associated invariant T cells respond to colonic microbiome alterations during acute HIV infection www.mucosalimmunology.org/article/S193...
Mucosal-associated invariant T cells respond to colonic microbiome alterations during acute HIV infection
Mucosal-associated invariant T (MAIT) cells are an unconventional subset of T cells that respond to vitamin B2 metabolites from a range of bacteria and fungi. We have previously reported that peripher...
mucosalimmunology.org
Airway epithelial cells as drivers of severe #asthma pathogenesis www.mucosalimmunology.org/article/S193...
@mucosalimmunol.bsky.social: Official Journal of @societymucosalimm.bsky.social is a proud bronze sponsor of #HavingIMPACTT2026 on Sept 28-30. They are generously sponsoring several of our presenter awards and 2 travel awards! Visit www.societymi.org to learn more about SMI and their journal.
Intestinal helminths skew dendritic cell development to counter the anti-helminth immune response from @annaandrusaite.bsky.social and @simmunology.bsky.social and colleagues: www.mucosalimmunology.org/article/S193...
Read the latest two #SMIMemberPaper by @girdhari_NCCS and colleagues in @J_Immunol how the CCR6-CCL20 axis impact IgA class-switching and how C3 deficient mice have higher NK activation with anti-tumor properties. Read more here: academic.oup.com/jimmunol/art...
CCR6-CCL20 signaling modulates immunoglobulin isotype switching at the mucosal barrier during gut inflammation
Abstract. Chemokine CCL20, secreted by gut epithelial cells, demonstrates markedly increased expression during episodes of chronic inflammation and infecti
academic.oup.com
#MucosalMonday and time for a new podcast episode! Get the latest research, hear what inspires @kathalahl.bsky.social, and learn all about #fungal species at the mucosa: www.iheart.com/podcast/269-...
Fungal Influences at the Barrier - Mucosal Immunology Podcast | iHeart
<p>Dr. Rossana Azzoni is in the Author’s Corner with Kathryn Knoop to discuss her work <a href='https://www.mucosalimmunology.org/article/S1933-0219(26)00037-1/fulltext'><u>Allergic lung in...
iheart.com
#MucosalVaccines Zymosan-adjuvanted intranasal norovirus virus-like particle vaccine induces antiviral mucosal immune responses in infant mice www.mucosalimmunology.org/article/S193...
Register today for Having #IMPACTT6: Advancing Microbiome Research Symposium @impactt-microbiome.bsky.social: www.impactt-microbiome.ca/having-impac...
Having IMPACTT 2026 Symposium - IMPACTT microbiome
Join us in 2026 in Canmore, AB, Canada for a 2.5 day in-person symposium dedicated to microbiome research.
impactt-microbiome.ca
Getting ready to teach #complement to new immunology trainees? Consider a new angle and incorporate all the ways “Local complement activation and modulation in mucosal immunity” www.mucosalimmunology.org/article/S193...
Local complement activation and modulation in mucosal immunity
The complement system is an evolutionarily conserved arm of innate immunity, which forms one of the first lines of host response to pathogens and assists in the clearance of debris. A deficiency in ke...
mucosalimmunology.org
Read the latest #SMIMemberPaper by @cjohansson_lab and colleagues in @PNASNews on how viral respiratory infections change lung metastasis. The IFN-a produced during viral infection reduced the ability of metastatic tumors to seed the lung. Read more here: www.pnas.org/doi/10.1073/...
Type I interferons induced upon respiratory viral infection impair lung metastatic initiation | PNAS
Metastatic breast cancer accounts for 7% of cancer-related deaths, with the lungs being a common site of cancer spread. In parallel, lower respirat...
pnas.org
Read the latest #SMIMemberPaper by Samuel Huber and colleagues in Nature Comms on how JAK inhibitors ameliorate #UC in a mouse model and human specimens by reducing IL1b. Read more here: www.nature.com/articles/s41...
Indirect inhibition of the NLRP3-interleukin-1β axis contributes to the efficacy of JAK1 inhibitors in experimental colitis and human ulcerative colitis - Nature Communications
The Janus Kinase inhibitors Tofacitinib, Upadacitinib and Filgotinib are used for the treatment of ulcerative colitis but the full mechanism of their action is not completely elucidated. Here the auth...
nature.com
Give the latest episode of MI podcast a listen, featuring @drsalinaslab.bsky.social, @marionpepper.bsky.social, @theonlylabever.bsky.social, @kknoop.bsky.social, @marionbrunck.bsky.social, and more!
Mucosal Immunology@mucosalimmunol.bsky.social · 3mo agoBonus #MucosalMonday MI Podcast! Straight from ICMI, get more thoughts from the ICMI speakers and hear from trainees at their posters. @theonlylabever.bsky.social @marionpepper.bsky.social www.iheart.com/podcast/269-...
Read the latest #SMIMemberPaper by Monica Gestal and colleagues in STAR Protocols by Cell Press on how to prepare lungs from infected mice while preserving the immunological architecture. Read more here: www.cell.com/star-protoco...
Protocol for visualization and quantitative analysis of murine lung immunological architecture using iBALT-UNMAP following bacterial challenge
The spatial distribution of adaptive immune cells is a critical determinant of the quality and magnitude of mucosal immunity. Here, we present a protocol for tyramide signal amplification (TSA) immuno...
cell.com
Mucosal BCG vaccination reprograms lung interstitial macrophages and enhances antimicrobial defense in mice a #resource from @immunologyking.bsky.social www.mucosalimmunology.org/article/S193...
Mucosal BCG vaccination reprograms lung interstitial macrophages and enhances antimicrobial defense in mice
Bacille Calmette–Guérin (BCG) is the only licensed vaccine against tuberculosis (TB) but provides inconsistent protection against disease. Alveolar macrophages (AM) are widely considered the primary m...
mucosalimmunology.org
Dysregulated MUC5B and MUC5AC impair epithelial barrier function and alter granulocyte frequency and activation in the lung and distal sites www.mucosalimmunology.org/article/S193...
The club cell circadian clock regulates temporal patterns in leukocyte trafficking in chronic allergic airways disease from @biologicaltimemcr.bsky.social , @hdurrington.bsky.social www.mucosalimmunology.org/article/S193...
New issue online! Read all about using #bioinformatics roadmap for characterizing the gut #microbiome and more! www.mucosalimmunology.org/issue/S1933-...
Beyond antibodies: Emerging roles of B cells in gastrointestinal inflammation and disease: www.mucosalimmunology.org/article/S193...
Bonus #MucosalMonday MI Podcast! Straight from ICMI, get more thoughts from the ICMI speakers and hear from trainees at their posters. @theonlylabever.bsky.social @marionpepper.bsky.social www.iheart.com/podcast/269-...
Career Opportunity: The University of Manitoba is recruiting a Canada Research Chair and Assistant/Associate Professor in Immunobiology of Chronic Disease Learn more and apply: www.societymi.org/page/CanadaR... #Immunology #AcademicJobs #ResearchJobs #CanadaResearchChair
Homeostatic and inflammatory functions of pulmonary GM-CSF from @christophschneider.bsky.social www.mucosalimmunology.org/article/S193...
Accumulation of mucosal and lymphoid hypo-functional granzyme K producing CD8+ effector memory T cells in idiopathic pulmonary fibrosis from @markesnyder.bsky.social www.mucosalimmunology.org/article/S193...
