Stephen P Juraschek, MD, PhD, FAHA, AHSCP-CHS
@spjuraschek.bsky.social
Internist, hypertension specialist, epidemiologist, and trialist interest in healthy food access, sodium, heart disease, blood pressure regulation, and gout
Happy to share our letter on the neutrality of the PCE to PREVENT transition in the 2025 Guidelines, using data from SPRINT. Really proud of the analysis led by Dr. Grobman new cardiology-bound intern at Vanderbilt! www.ovid.com/10.1097/HJH....
Hypertension treatment and risk of cardiovascular... : Journal of Hypertension
The 2025 AHA/ACC blood pressure (BP) management guidelines recommend BP treatment for 10-year cardiovascular disease (CVD) ≥7.5% from the PREVENT...
ovid.com
Excited to share our article on orthostatic hypotension among adults age 78 yr and older led by Dr. Khan. Timing of Orthostatic Blood Pressure Changes and Its Association With Orthostatic Symptoms and Falls at Very Old Ages: Findings From the ARIC Study www.ahajournals.org/doi/10.1161/...
Timing of Orthostatic Blood Pressure Changes and Its Association With Orthostatic Symptoms and Falls at Very Old Ages: Findings From the ARIC Study | Hypertension
BACKGROUND: Assessment and treatment of orthostatic hypotension (OH) are recommended to prevent falls in older adults. However, the optimal timing of standing blood pressure (BP) assessments to identi...
ahajournals.org
Excited to share our insights on motivational themes in digital ads for more efficient trial recruitment. Bottom line: it's more than click-through rate! Motivational themes in digital advertisements enhance recruitment efficiency in cardiovscular trials www.sciencedirect.com/science/arti...
sciencedirect.com
Check out this scholarship opportunity in honor of George Bakris: George Bakris Scholarship Program 2026 | Cardiometabolic Health Congress www.cardiometabolichealth.org/george-bakri... I'm looking forward to participating in this conference this year. The line up looks great! Join us!
George Bakris Scholarship Program 2026
CMHC is accepting applications for the 2026 George L. Bakris Scholarship Program, honoring Dr. Bakris' commitment to cardiorenal metabolic medicine education.
cardiometabolichealth.org
Happy to share our thoughts on the role of renal denervation in resistant hypertension inspired by this nice JAMA review article. Review of Diagnosis and Management of Resistant Hypertension jamanetwork.com/journals/jam...
Review of Diagnosis and Management of Resistant Hypertension
To the Editor We read with interest the recent comprehensive Review on the management of resistant hypertension.1 We have concerns, however, about a disconnect between the article’s evidence and the a...
jamanetwork.com
Nice article on hospitalized patients with hypertension: 25% had orthostatic hypotension with alpha blockers being a common risk factor. link.springer.com/article/10.1...
Orthostatic Hypotension in Hypertensive Patients Hospitalized in Italian Internal Medicine Departments: FADOI-HYP-OP Study - High Blood Pressure & Cardiovascular Prevention
Introduction Orthostatic hypotension (OH) is defined as a decline in systolic blood pressure of at least 20 mmHg or a reduction in diastolic blood pressure of at least 10 mmHg, within the first 3 min ...
link.springer.com
Interesting study on immediate OH and falls. Like our STURDY paper on timing, sustained seems more problematic, but in ARIC the early measures were especially associated with falls. academic.oup.com/ageing/artic...
Does immediate orthostatic hypotension in adults have clinical implications for syncope and falls? An analysis of the Irish longitudinal study of ageing
AbstractBackground and Aims. Orthostatic hypotension is a common cause of syncope and falls; however, it is unclear if the association differs by variant.
academic.oup.com
Excited to share this paper by medical student and brilliant scientist Frances Wang, who shows that high-quality home monitoring can be simple for older adults! Optimizing Home Blood Pressure Monitoring Protocols in Older Adults academic.oup.com/ajh/article-... @amjhypertension.bsky.social
Optimizing Home Blood Pressure Monitoring Protocols in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study
AbstractBackground. Current clinical guidelines recommend home blood pressure monitoring (HBPM) to confirm hypertension diagnosis, guide therapy, and suppo
academic.oup.com
Supine hypertension strikes again...this time afib! academic.oup.com/europace/art...
Validate User
academic.oup.com
Super important work on GLPs and something I've personally encountered as a physician... www.medscape.com/viewarticle/...
GLP-1s Tied to Higher Risk for Dizziness, Fainting for Some
Hypotension-related events increased after starting GLP-1s in patients taking multiple antihypertensive medications.
medscape.com
This study found an association between OH and white coat as well as OHTN and masked hypertension. Similar to what we found in SPRINT, CRIC, and ARIC. @patildhrumil.bsky.social pubmed.ncbi.nlm.nih.gov/42267569/
Association between orthostatic blood pressure change and masked and white coat hypertension: the Nagahama study - PubMed
We identified a physiological association between exaggerated postural BP variability and office-to-home BP differences, which were previously considered unrelated.
pubmed.ncbi.nlm.nih.gov
I like how this paper questions the traditional view that OH in diabetes is neurogenic...I wouldn't be surprised if cardiovascular disease/hypertension were much more common contributors! www.mdpi.com/2227-9032/14...
mdpi.com
Nice cross-sectional paper on antihypertensive drug class and out of office blood pressure patterns. www.nature.com/articles/s41...
Relationship between medication class and ambulatory blood pressure profile in the chronic renal insufficiency cohort (CRIC) study - Journal of Human Hypertension
Journal of Human Hypertension - Relationship between medication class and ambulatory blood pressure profile in the chronic renal insufficiency cohort (CRIC) study
nature.com
Neat validation-style study showing good PPG performance compared to ABPM including sleep dipping. Now can it track changes in BP after medication titrations? Photoplethysmography based remote cardiac blood pressure: Blood Pressure Monitoring journals.lww.com/bpmonitoring...
journals.lww.com
Thanks Dr. Foti for calling my attention to this article. Selective remeasurement of high BPs to improve control rates can lead to less intensive treatment and won't prevent CVD events. Evaluating the Consequences of a Hypertension Management Incentive jamanetwork.com/journals/jam...
Evaluating the Consequences of a Hypertension Management Incentive
This quasi-experimental study examines the association of a physician-facing quality metric and financial incentive for hypertension management with clinical decisions and health outcomes for patients...
jamanetwork.com
We have more ways to measure blood pressure than ever before but not necessarily more confidence in what those measurements mean. Our NHLBI workshop report in @jaccjournals.bsky.social chaired w/ @spjuraschek.bsky.social provides an implementation roadmap. www.sciencedirect.com/science/arti...
Blood Pressure Assessment Across the Lifespan: Improving Clinical Research and Clinical Practice: A National Heart, Lung, and Blood Institute Workshop Report
Hypertension is a modifiable risk factor for cardiovascular disease (CVD) and its prevalence is high in the United States and worldwide. Adequate char…
sciencedirect.com
This is a nice letter on home blood pressure protocols for postprandial hypotension. More research is needed on this topic. Home monitoring may be one strategy. pubmed.ncbi.nlm.nih.gov/42145048/
Individualized Home Blood Pressure Monitoring and Postural Timing Strategies for Postprandial Hypotension: A Rehabilitation Perspective - PubMed
Individualized Home Blood Pressure Monitoring and Postural Timing Strategies for Postprandial Hypotension: A Rehabilitation Perspective
pubmed.ncbi.nlm.nih.gov
This is a great read led by brilliant, aspiring geriatrician and current resident, Aldis Petriceks. Evaluation and Management of Hypertension in Older Adults - Clinics in Geriatric Medicine www.geriatric.theclinics.com/article/S074...
Evaluation and Management of Hypertension in Older Adults
Hypertension is the most diagnosed condition among adults aged 60 years and older and is a major contributor to morbidity and mortality. In this article, we review current evidence on blood pressure e...
geriatric.theclinics.com
Lots of easter eggs in this paper...not including the 100 page supplement!!! The incoming IM intern Dr. Mate-Kole did a phenomenal job with the rigorous peer review. Orthostatic Blood Pressure, Cardiovascular Disease, and Hypotensive Events | Hypertension www.ahajournals.org/doi/10.1161/...
Orthostatic Blood Pressure, Cardiovascular Disease, and Hypotensive Events | Hypertension
BACKGROUND: Orthostatic hypotension is thought to be associated with coronary heart disease, falls, and syncope due to low blood pressure (BP) upon standing. METHODS: The ARIC study (Atherosclerosis...
ahajournals.org
Check it out! Low vs high spironolactone... No difference in BP or renin or hyperkalemia...but more side effects from high spiro in men. ahajrnls.org/4fnEa6U
American Heart Association Journals
ahajrnls.org
Excited to share this summary of our workshop related to blood pressure assessment in collaboration with hypertension experts and NIH/NHLBI! www.sciencedirect.com/science/arti...
Blood Pressure Assessment Across the Lifespan: Improving Clinical Research and Clinical Practice: A National Heart, Lung, and Blood Institute Workshop Report
Hypertension is a modifiable risk factor for cardiovascular disease (CVD) and its prevalence is high in the United States and worldwide. Adequate char…
sciencedirect.com
Fascinating study showing that low BP is important for cerebral hypoperfusion. pubmed.ncbi.nlm.nih.gov/42034685/
Orthostatic hypotension without co-existent supine hypertension is associated with impaired cerebral oxygenation: findings from the Irish Longitudinal Study on Ageing (TILDA) - PubMed
Hypertension and orthostatic hypotension (OH) are common in older age, with both conditions recognized as risk factors for cardiovascular disease and end organ damage. Cerebral hypoperfusion is postul...
pubmed.ncbi.nlm.nih.gov
Apply for our @amjhypertension investigator award!
Excited to share this super comprehensive review article led by brilliant @harvard.edu medical student, Shreyas Rajesh, on hypertension agents and OH...love the framework below! link.springer.com/article/10.1...
A Review of Clinical Trial and Meta-Analyses of BP Treatment Strategies for Patients with Orthostatic Hypotension: Blood Pressure Management in Patients with Hypertension and Orthostatic Hypotension -...
Current Hypertension Reports - To review clinical trial and meta-analysis data on the effects of blood pressure (BP) pharmacologic treatment for hypertension on orthostatic hypotension (OH) to...
link.springer.com
Important paper with similar findings to our own in ARIC: Limited evidence in support of sex-specific HTN thresholds pubmed.ncbi.nlm.nih.gov/41532301/ Sex Differences in Blood Pressure and Cardiovascular Disease in the UK Biobank: A Prospective Cohort Study academic.oup.com/ajh/article/...
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pubmed.ncbi.nlm.nih.gov
Interesting paper - Factors Associated With Discussing High Blood Pressure Readings in Clinical Notes. Naturally, nephrology, transplant, internal med are discussing the most (it's part of the job). ID, endocrine, sports medicine and GI > than cardiology? pubmed.ncbi.nlm.nih.gov/39661402/
I agree with this. Although it's based on observational data (so far), using renin as a biomarker when medically treating PA is part of the endo society guideline. I titrate MRA until renin rises, then if needed utilize A/C/D. tinyurl.com/yksmf5y8
How prominent is AI in your scholarship? Personally I feel like Journals should have AI disclosures for every article - since even literature searches often involve some degree of AI....but lines get really blurry about writing vs editing, data analysis vs management, etc...
I'm seeing more spironolactone monotherapy for medical management of non-lateralizing PA. Any evidence for this practice? I confess my conservative thinking is to adhere to evidence-based practice with some firstline agents for BP management (vs maxing out spiro alone). Thoughts?
