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#Osteoporosis is a common complication among pediatric patients with chronic #LiverDisease. But challenges remain not only for detecting and treating osteoporosis, but also for managing and monitoring vertebral fractures. 👉️ buff.ly/PESHQu8 #PediatricMed

Clinical insights into the association between chronic liver disease and osteoporosis

Osteoporosis is a common complication among pediatric patients with chronic liver disease. But challenges remain not only for detecting and treating osteoporosis, but also for managing and monitoring…

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#MedCase - A novel homozygous TG gene variant was identified in a newborn baby who presented with severe respiratory failure and perinatal asphyxia secondary to tracheal compression caused by a massive congenital #goiter. 👉️ buff.ly/mrFYG7W #EndoSky

A novel homozygous thyroglobulin gene variant presenting with massive congenital goiter and neonatal airway obstruction

A novel homozygous TG gene variant was identified in a newborn baby who presented with severe respiratory failure and perinatal asphyxia secondary to tracheal compression caused by a massive…

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Type 3 autoimmune #pancreatitis has been proposed as a form of pancreatic injury induced by ICIs, but diagnosis is complicated, the role of available therapeutic options is uncertain, and no clear management guidelines exist. 👉️ buff.ly/Y6jpI9s #GISky

Type 3 Autoimmune Pancreatitis: What Do We Know So Far?

AIP-3 has been proposed as a form of pancreatic injury induced by immune checkpoint inhibitors, but diagnosis is complicated, the role of available therapeutic options is uncertain, and no clear…

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#MedCase - This case series reports three patients with the Omicron variant of SARS-CoV-2 who presented with acute myocardial infarction due to coronary thrombosis, without underlying atherosclerotic plaques. 👉️ buff.ly/aKZfLAr #CardioSky #COVID19

Coronary thrombosis without underlying atherosclerotic plaque in patients with Omicron variant of coronavirus disease 2019: a case series

This case series reports three patients with the Omicron variant of SARS-CoV-2 who presented with acute myocardial infarction due to coronary thrombosis, without underlying atherosclerotic plaques.

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#MedNews - Elevated levels of interferon-α may drive an immunological endotype of #SjögrenDisease, and could offer a novel treatment target for the condition. 👉️ buff.ly/lcEKSFI #RheumSky

Elevated IFNα may signal distinct Sjögren disease subtype

Elevated levels of interferon-α may drive an immunological endotype of Sjögren disease, and could offer a novel treatment target for the condition.

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Exogenous #CushingSyndrome is typically caused by therapeutic glucocorticoids, but adulterated natural remedies, compounds with intrinsic glucocorticoid-like activity, and factitious glucocorticoid intake may also be responsible. 👉️ buff.ly/Yec8Voe #EndoSky #MedSky

Rare causes of exogenous Cushing’s Syndrome: a challenge for endocrinologists

Exogenous Cushing syndrome is typically caused by therapeutic glucocorticoids, but adulterated natural remedies, compounds with intrinsic glucocorticoid-like activity, and factitious glucocorticoid…

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#MedCase - A case of cutaneous #angiosarcoma in a patient with a BMI over 100 kg/m2 that draws attention to the diagnostic and therapeutic barriers in people with class III obesity. 👉️ buff.ly/istZlA8 #OncSky #MedSky

Cutaneous angiosarcoma in a super-morbidly obese patient (body mass index 106.7 kg/m2) highlighting diagnostic and therapeutic barriers in extreme obesity: a case report

A case of cutaneous angiosarcoma in a patient with a BMI over 100 kg/m2 that draws attention to the diagnostic and therapeutic barriers in people with class III obesity.

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Transesophageal echocardiography plays a pivotal role in preprocedural screening and intraprocedural guidance for transcatheter tricuspid valve interventions. Find out more 👉️ buff.ly/z9NdZIG #CardioSky #TTVI

Echocardiographic guidance in transcatheter tricuspid valve interventions

Transesophageal echocardiography plays a pivotal role in preprocedural screening and intraprocedural guidance for transcatheter tricuspid valve interventions. This imaging review details the…

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#MedNews - Emulation studies of #GLP1 receptor agonist use in adults with #diabetes suggest treatment may protect against fragility fracture but increase the risk for incident alopecia. 👉️ buff.ly/yxcQicm

GLP-1 receptor agonist relationship to fragility fracture and alopecia clarified

Emulation studies of glucagon-like peptide-1 receptor agonist use in adults with diabetes suggest treatment may protect against fragility fracture but increase the risk for incident alopecia.

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What is the prevalence of cachexia in metastatic #BreastCancer, what are the systemic and local muscle cues leading to its development, and how can animal models further our understanding? Find out here 👉️ buff.ly/8tRc2LJ #OncSky

Understanding cachexia and muscle dysfunction in the context of metastatic breast cancer

What is the prevalence of cachexia in metastatic breast cancer, what are the systemic and local muscle cues leading to its development, and how can animal models further our understanding?

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#MedCase - A woman with #T2D developed severe hypoglycemia after postoperative renal dysfunction unmasked prolonged cibenzoline intoxication. ECG and C-peptide assessments may be useful when cibenzoline intoxication is suspected. 👉️ buff.ly/nZy7yqF #EndoSky

Postoperative renal dysfunction-induced severe hypoglycemia associated with unrecognized cibenzoline intoxication in a patient with type 2 diabetes mellitus: a case report with review of literature

A woman with type 2 diabetes developed severe hypoglycemia after postoperative renal dysfunction unmasked prolonged cibenzoline intoxication. ECG and C-peptide assessments may be useful when…

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#MedNews - Systemic exposure to nicotinamide may reduce the risk of patients with ocular hypertension progressing to primary open-angle #glaucoma and receiving subsequent interventions. 👉️ buff.ly/6XdCquU #EyeSky

Nicotinamide exposure may reduce open-angle glaucoma risk in ocular hypertension

Systemic exposure to nicotinamide may reduce the risk of patients with ocular hypertension progressing to primary open-angle glaucoma and receiving subsequent interventions.

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Does adipose dysfunction drive #T2D progression? Discover how it triggers a pathological cascade that induces systemic insulin resistance, impairs pancreatic β-cell function, and disrupts interorgan communication in this review. 👉️ buff.ly/k9SnZlf #MedSky #Diabetes

Lipid Metabolic Disorders: a Pivotal Driver in Type 2 Diabetes Mellitus Pathogenesis

Adipose dysfunction acts as the initiating event, triggering a pathological cascade that induces systemic insulin resistance, impairs pancreatic β-cell function, and disrupts interorgan communication.

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#MedNews - Intentional weight loss with a low-energy diet replacement program prior to #EndometrialCancer surgery is feasible and reduces the risk for complications in women with overweight or obesity. 👉️ buff.ly/15HxkLh #OncSky

Intentional weight loss may protect against endometrial cancer surgery complications

Intentional weight loss with a low-energy diet replacement program prior to endometrial cancer surgery is feasible and reduces the risk for complications in women with overweight or obesity.

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Join Prof. Elena Nikiphorou to explore the key issues in difficult-to-treat #RheumatoidArthritis, from its definition and underlying contributors to treatment and management strategies. Register now for this free webinar 👉️ buff.ly/ioH94Pz #MedSky #RheumSky

#MedNews - The risk for serious or outpatient infections among children and adolescents with inflammatory bowel disease is similar with infliximab and adalimumab. Full story 👉️ buff.ly/01E476s #GISky #PediatricMed

Infliximab, adalimumab have similar infection risk profiles in pediatric IBD

The risk for serious or outpatient infections among children and adolescents with inflammatory bowel disease is similar with infliximab and adalimumab.

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Exercise is a disease-modifying therapy for #MASLD that has multisystem benefits, but plans should be individualized, structured, and progressive. Could a proposed new framework provide a standardized pathway for clinical practice? 👉️ buff.ly/ELcSR9p #LiverSky

Prescribing Exercise in MASLD: From Evidence to a Structured, Measurable Intervention

Exercise is a disease-modifying therapy for MASLD that has multisystem benefits, but plans should be individualized, structured, and progressive. Could a proposed new framework provide a standardized...

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DKA is a recognized precipitating factor for AEN, but the clinical characteristics of DKA-associated AEN have not been well defined. What do we know about its clinical presentation, endoscopic findings, management, and outcomes? 👉️ buff.ly/PQomvC6 #GISky #Diabetes

Acute esophageal necrosis in patients with diabetic ketoacidosis: a systematic review of clinical features and outcomes

DKA is a recognized precipitating factor for AEN, but the clinical characteristics of DKA-associated AEN have not been well defined. What do we know about its clinical presentation, endoscopic…

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MCA offers an alternative to suturing or stapling techniques for maintaining the continuity of the intestine, but its clinical application remains limited due to scarce evidence. What does early experience tell us? 👉️ buff.ly/ZJr7Ot0 #GISky #GISurgery

Magnetic compression anastomosis in gastrointestinal surgery: a systematic review of early human experience

MCA offers an alternative to suturing or stapling techniques for maintaining the continuity of the intestine, but its clinical application remains limited due to scarce evidence. What does early…

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