🧪 We have a new publication out in @NatureComms. 🧪Great collaborative work involving @KclRandallMol, @dsb_unipd, @PhD_DSB_UniPD, @cnr_scitec, @humantechnopole. Here's the link www.nature.com/articles/s41...
Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail - Nature Communications
Kinesin-1 utilizes ATP-driven conformational changes to transport vital intracellular cargoes along microtubules. The authors use cryo-EM to reveal a missing structural transition state of the kinesin...
nature.com