Thatβs a wrap on #ADASciSessions 2026. Science. Stories. Sketchnotes. And a week that reminded us why academic freedom matters. The science goes on. @amdiabetesassn.bsky.social #ADASciSessions #Sketchnotes #MedEd #ScienceIsNotSilent
Stephen Stone, MD π¬π§¬πβοΈ
@stevestonedraws.bsky.social
Peds Endo & Physician Scientist | Amateur Medical Illustrator | Live Sketchnotes | Dabbles in Python | Tweets are my own | Reposts != Endorsement | bmc.link/DiabetesNinja | stonelab.wustl.edu
Some heroes wear backpacks. Colleagues at #ADASciSessions were removed by police for distributing a Diabetes Care editorial, raising concerns about political interference in science. Censorship is real. Stand up. Read it. Sign it. @amdiabetesassn.bsky.social #ADASciSessions #ScienceIsNotSilent
@lilamd.bsky.social at PPI: Norovirus is a major cause of infant morbidity & mortality β not just a cruise ship nuisance! Interferon is a key mediator, but gaps in our understanding of the human norovirus receptor make culture models a real hurdle. #Norovirus #InfectiousDisease #PedsResearch
π« Deepika Polineni, MD MPH at PPI: CF care has transformed β 90-95% of US patients now qualify for CFTR modulators! But thereβs still much to learn, and new clinical trial endpoints are key to helping every patient with CF. Remarkable work! #CysticFibrosis #CFTRModulators #PedsResearch
MASLD in kids: more common than expected, linked to long-standing obesity, maternal metabolic health, gut microbiome shifts, bile acid changes & early risk factors like low birth weight + catch-up growth. π¨ Dr. Mike Thompson, MD PhD #MASLD #PedsEndo #Obesity @hepatocrinologist.bsky.social
Infant seizes post-breastfeeding, BG 44 mg/dL. Critical sample: elevated insulin, positive glucagon test, elevated ammonia. Dx: HI/HA Syndrome, de novo GLUD1 variant. Responds to diazoxide + low protein diet! π¨ Dr. Renad Al-Mefleh, MD #PedsEndo #Hypoglycemia #RareDiseases #GLUD1 #Hyperinsulinism
π¨ BZZZZZ! CLANK! Dr. Jennifer Wambach, MD gave a fantastic PPI talk on ABCA3 surfactant biology, 3D alveospheres, lipidomics, and lentiviral gene therapy β all while construction raged behind the wall. Unbothered. Inspiring. #LungDisease #GeneTherapy #PedsResearch
Sam Cortez, MD on Turner Syndrome at the #PCTI Seminar Series: single X chromosome, risks for ovarian failure and cardiovascular disease, and oral estrogen raises estrone while avoiding hepatic first-pass metabolism. What IS the best route? #TurnerSyndrome #PedsEndo #Endocrinology #PedsResearch
Honored to present our lab's research on Familial Partial Lipodystrophy at the 2026 WashU Pediatric Research Retreat! π¬ iPSC-derived adipocytes + human adipose snRNA-Seq = new insights into a rare & complex disease. #Lipodystrophy #RareDisease #StoneLab #PedsResearch
Incredibly proud of post-bacc McKinlee Gobble presenting her poster on FGF21 signaling & insulin-mediated pseudoacromegaly at the 2026 WashU Pediatric Research Retreat! π Rare disease research, big impact. #FGF21 #RareDisease #PedsResearch #StoneLab
Stone Lab representing at the 2026 WashU Pediatric Research Retreat! π§ͺπ So proud of this team β the science, the energy, the people. This is what pediatric research looks like! #StoneLab #PedsResearch #Pediatrics #ResearchRetreat
Dr. Gary Silverman's final message as Chair of WashU Pediatrics at our Research Retreat hit differently. π Take care of yourself. Take care of your family. Take care of your patients. A legacy of humanity and leadership. #Pediatrics #PhysicianWellness #Leadership #MedEd
Dean David Perlmutter, MD opened our Pediatric Research Retreat with a powerful keynote on Alpha-1 Antitrypsin Disease π¬ Genetic modifiers + autophagy-targeting drugs = incredible promise for liver disease! #Alpha1 #Autophagy #PedsResearch #LiverDisease @washumedicine.bsky.social
Amino acids compensate for MPC metabolism in hepatocytes, BCAAs & pyruvate share similarities, & PPM1K phosphorylation β in obese livers. Mouse CRISPR model insights! π¨ Dr. Brian Finck, PhD at WashU #Metabolism #BCAA #LiverMetabolism #MetabolicResearch #MedEd @beineff.bsky.social
Immune checkpoint inhibitors β autoimmune diabetes risk, especially with pre-existing T2DM. Rapid C-peptide loss makes management tough. π¨ Sketchnotes from Dr. Huda Al-Bahadili, MD's WashU lecture #ICI #Endocrinology #DiabetesAwareness #Oncology #T2DM
π¦ Drew Schwartz, MD PhD on the neonatal microbiome: prematurity impairs microbiome development, abnormal flora drives systemic infections, and IgA/IgG play fascinating roles in immunity. Critical work for our tiniest patients! #Microbiome #Neonatology #Immunology
Congenital #hyperinsulinism: common, high stakes, and historically limited treatment options.From neurologic risk of hypoglycemia to feeding challenges and emerging therapies, this CME webinar highlighted why innovation in HI is urgently needed. Exciting science ahead. #MedEd #PedsEndo
Amazing PPI presentation by Dr. Nicole Brossier on NF1, neurodevelopment, and tumor biology. Striking evidence that maternal obesogenic diet influences optic pathway glioma risk β with growth factor signaling driving the connection. Thought-provoking work. π§ β¨ #PPI @washumedicine.bsky.social
Amazing PPI presentation by Dr. Danielle Alfano exploring ADAM10 in sepsis biology. Loved the mechanistic insights into endothelial dysfunction, VE-cadherin shedding, and TAILS-based substrate discovery. Translational science at its best. π§¬π₯ #PPI @washumedicine.bsky.social
Fantastic talk by Dr. Aisha Ansar on monogenic diabetes. GCK-MODY causes mild, stable hyperglycemia with preserved C-peptide, negative antibodies, and low complication riskβcritical to recognize when evaluating patients with atypical diabetes. #MonogenicDiabetes #MODY @washumedicine.bsky.social
Amazing presentation by Dr. Lori Holtz on the human virome. Loved learning how viral communities can shape health and disease, and the striking motherβchild data showing high EBV levels and CMV links to maternal infection risk. Thought-provoking science! π§¬π #PPI
Dr. Monika Bambouskova unpacks mevalonate kinase deficiency as both an inborn error of metabolism and immunity. From why statins are ineffective to IgD+ B-cell biology and isoprenoid supplementationβimmuneβmetabolic insight in action. #RareDisease #Immunology #Metabolism @washumedicine.bsky.social
Isabelle South, PA breaks down how people with diabetes use social media: a double-edged sword that can spread misinformation, but also deliver practical insulin pump guidance, lifestyle tips, and humanity through humor. #DiabetesEducation #HealthCommunication @washumedicine.bsky.social
Amazing presentation by Dr. Nicole Gilbert on the vaginal microbiome and #UTI risk. Loved the deep dive into community state types, Gardnerella clades that can infect the bladder, and how shotgun metagenomics is changing what we see. π§¬π #PPI @washumedicine.bsky.social
Impressive talk by Dr. Dustin Baldridge tackling one of the biggest challenges in genomics: variants of uncertain significance. Deep mutational scanning is pushing us toward real answers β and real clinical impact. Powerful stuff. π§¬π₯ #PPI #VUS #Genetics @washumedicine.bsky.social
Big congratulations to Alex Li on passing his Qualifying Exam! π An impressive presentation spanning population genetics, Wolfram spectrum phenotypes, and future functional genomics approaches. Excited to see where this work goes next! @washumedicine.bsky.social #WolframSyndrome
Such an impressive talk by Dr. Michelle Gill! 𧬠From IL-4 as a central mediator in atopic asthma to the mysteries of IL-4RΞ± blockade and evolving trial designs β this session beautifully linked fundamental immunology with clinical impact. #PPI @washumedicine.bsky.social
Such an inspiring grand rounds presentation by Dr. Linda DiMeglio today π. Weβve come so far since the first purified insulin, and now teplizumab marks the first true disease-modifying therapy for diabetes. Universal screening, new trial designs, and big leaps ahead! @drdimeglio.bsky.social #EndoSky
Pediatric Endocrinology Wrapped 2025 πΆ My year in hormones, growth charts, and CGM alarms I definitely slept through. See what really topped the charts this year. #PedsEndo #SpotifyWrapped #EndoLife #EndoSky