@striepenlab.bsky.social
Sebastian Shaw@millseba.bsky.social · 9mo agoGrateful to all mentors, peers, friends, and family who supported me — especially my wife, Natalie. ❤️ Special thanks to @striepenlab.bsky.social, for freedom, trust, and inspiration at @upenn.edu. One lasting lesson: admire what worked before worrying about what didn’t.
Our latest story on Clofazimine resistance in Cryptosporidium! What started as a side project turned into one of the most interesting stories. Genetics 101 😊 #Cryptosporidium #Apicomplexa #Clofazimine #AntimicrobialResistance #AMR #ParasiteResearch www.biorxiv.org/content/10.1...
Widespread genomic heterogeneity at the type II NAD(P)H dehydrogenase locus predisposes Cryptosporidium to clofazimine resistance
The parasite Cryptosporidium is a leading cause of life-threatening diarrheal disease, and effective treatment is not available. The discovery of potent anti-Cryptosporidium activity of clofazimine, o...
biorxiv.org
After this weekend’s extensive firings at NIH and CDC - focused mainly on young scientists - like the ENTIRE class of epidemic intelligence service - I have a hard time to choose my music. This is the closest I have been to bitter - in my 30 years in US science.
Global Parasitology Seminar next Monday: Ira Blader on Toxoplasma & oxygen. 2/10/25 12 pm EST in person & zoom. @TrendsParasitol @BSPparasitology @parasitesrule @AmSocParasit @AS_Para @pennvet @SFParasitologie @CTEGD
As the days begin to wear on me and I wake up with more worry than usual I saw this (posted by ‘English Literature’) … and it saved some part, of a day I rued.
First Global Parasitology Seminar of 2025: Nathan Schmidt on Malaria & Microbiome. Monday 01/27 12 pm US EST. @womeninmalaria @BSPparasitology @FightingMalaria @AmSocParasit @UPenn_I3H @MBLBoP
Are you interested in #trypanosomes #biomolecularcondensates and/or #geneexpression? We are looking for a highly motivated postdoc to work with with us in the beautiful city of York! Please share! jobs.york.ac.uk/vacancy/post...
Come and celebrate the exceptional career of Mark Carrington (24th March at University of Cambridge)!
British Society for Parasitology@bspparasitology.bsky.social · 2y ago🚨 Retirement Symposium for Prof Mark Carrington of the University of Cambridge Our #Trypanosoma colleagues may want to attend this symposium in Cambridge on the 𝟐𝟒𝐭𝐡 𝐨𝐟 𝐌𝐚𝐫𝐜𝐡, 2025 (register by the 15th!) - Details at QR code & tinyurl.com/2uw8tryu
Go and see a new picture of the handsome Dr. Hunter who was elected a Distinguished Fellow of the The American Association of Immunologists for 2025! Congrats! https://www.aai.org/Awards/Career-Awards/Distinguished-Fellows-of-AAI/Current-Recipients?utm_source=community_alert&utm_medium=email_header…
The American Association of Immunologists - Current Recipients
This program annually recognizes members for distinguished careers and outstanding scientific contributions as well as their service to AAI and the immunology community. Click here for more…
buff.ly
Delighted to share our study on a major Toxoplasma virulence factor that prevents lytic host cell death. Many thanks to @parafrap.bsky.social for support, constructive reviews and all labs involved: Melissa Lodoen, Hiba El Hajj, @gissotlab.bsky.social, Karine Le Roch Link : rdcu.be/d6m3G
The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell death
Nature Communications - Ruivo et al uncover a Toxoplasma survival mechanism conserved across different cell types and species. By repressing NF-kB activation and lytic host cell death pathways, the...
rdcu.be
Don’t miss Yi-Wei summarizing his amazing work as an Assistant Professor. This will be both, great science and a lot of fun!
Terrific new paper on C. hominis pathogenesis: Multicopy subtelomeric genes underlie animal infectivity of divergent Cryptosporidium hominis subtypes | Nature Communications https://buff.ly/4fPE4li
Multicopy subtelomeric genes underlie animal infectivity of divergent Cryptosporidium hominis subtypes - Nature Communications
This study reveals that the genomes of animal-adapted Cryptosporidium hominis subtypes differ from common human subtypes in the copy number of subtelomeric MEDLE genes, contributing to their…
buff.ly
Belated holiday wishes everyone! I don’t have a Christmas sweater in me but Bethan Wallbank suggested this as closer to my persona. BTW if you (like me) are still figuring out whether to ditch X for bluesky, try the app called buffer where you can do both with one post for now.
