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Showcasing the best writing, video, and podcasts from the publishers and creators using Substack. Download the app: https://substack.com/app

"Between 100,000 and 140,000 Americans die each year due to alcohol, which is 2–3 times as many people as are killed by guns in America each year." Andy Masley argues we have an ethical obligation to denormalize alcohol

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When Jeff Stein reported on Pentagon health official Keith Bass, Bass sued for $1 million. Through the Substack Defender program, we helped Jeff secure local counsel and fight back. Last week, Jeff won—the case was dismissed with prejudice. Read Jeff's post: www.spytalk.co/p/how-i-bea...

How I Beat a Trump Official's Nasty Lawsuit

Keith Bass, former head of the CIA’s Medical Office, sued me for a million bucks. Substack's Defender program came to my aid.

spytalk.co

🗣️ NEW ON SUBSTACK: Group DMs. Create a groupchat with your friends on the Substack app or Substack desktop. Add and remove members, and rename the chat. Group members can invite others and leave whenever they want

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In this chat with Richard V Reeves, Darby Saxbe shares insights from her new book Dad Brain on how parenthood changes men neurologically, and what we can learn about human fatherhood from mountain gorillas

Screwworm is a devastating scourge for farmers, and the US is suffering its first infestation since the 1980s. Brian Pottertakes a deep dive into why the barrier at Panama failed, and why re-eradicating screwworm will take "close to a decade of sustained work" and hundreds of millions of dollars

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From 2024: Celine Nguyen's mega-viral post why the the best content on the internet is created by people who've turned research into a leisure activity, unconstrained by credentials and institutions - link in replies

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"What game are you playing? What's your theory of the game?" LinkedIn founder Reid Hoffman explains what sets top-performing founders apart, in this excerpt from Mark Pincus's new book - link in replies

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“We pass the savings on to the customer, every time. Do you know how tempting it is to make another $7 on a pair? But once you do it, it’s like taking heroin. You can’t stop.” Trung Phan on Costco founder Jim Sinegal's formula for building Kirkland Signature into a $90 billion brand

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"We effectively end up comparing a new technology to perfection, so it's no wonder it comes up short." Psychologist Paul Bloom on why the media's reaction to a Waymo running over a cat shows how gut responses can be misleading

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“Your consumption ‘diet’ establishes your creation capacity.” Writer, investor, and entrepreneur Sahil Bloom on the four types of professional time - and how to protect your calendar so you can make progress every day

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Scott Galloway argues GLP-1s are “a fully loaded magazine of silver bullets” to fix Americans' worst chronic conditions, but the benefits are undermined when patients quit due to cost - link in replies

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"Agents are bad at checking their own work since they’re often unaware of their own blind spots." @jinayoon_ from Posthog on how to make code review suck less - link in replies

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From 2022: “‘Say more’ and ‘care to elaborate’ are magical phrases.” Sasha Chapin on how to have better conversations

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"I never thought I would be a writer. I don't even look the part. I’m a big dumb meathead who fell in love with deep ideas." Dan Koe on how the writing habit can transform how your brain interacts with reality - link in replies

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In 1775, a Harvard professor estimated the US population would hit 1.28 billion by the year 2000 - but "we came in about a billion short." Rob Henderson on what new research tells us about America's fertility collapse and how we might fix it

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From an experimental cancer therapy that makes mutant cells self-destruct, to a synthetic cell called SpudCell that can eat, grow, and divide, Saloni Dattani and Niko McCarty share the most exciting recent innovations in biotech & medicine - link in replies

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Unemployment is low, and real median incomes high. So why are young people so miserable? Johann Kurtz: "I think we’re clearly in the midst of a tremendous measurement failure"

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With Europe getting cooked by intensifying heat waves, climate change "has morphed into an all-purpose causal explanation for extreme weather events." But that phrase describes an outcome, not a cause, says Roger Pielke Jr.

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"The generation entering law school and frankly those entering the profession are AI natives. They are going to use AI no matter what anyone says." @stevesi on why AI in the classroom can't be stopped - and shouldn't be

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Why are most good ideas "born as twins"? Bestselling author David Epstein on why simultaneous discovery is so common, and why question-framing is "the great bottleneck of progress"

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