Sylvain Baillet
@sylvainbaillet.bsky.social
Director, Research & Innovation, University of Montreal Health Centre (CHUM), and Director CHUM Research Centre (CRCHUM) | Professor, Neuroscience @ University of Montreal.
Pain avoidance can protect us, but in chronic pain, it can become part of the problem. Our new collaborative study reveals altered pain-avoidance learning in CRPS, linked to anxiety and reduced prefrontal alpha activity. doi.org/10.1002/ejp.... #CRPS #PainResearch @crchum.bsky.social
New collaborative review of neurophysiological alterations in severe mental illness. 👇 www.sciencedirect.com/science/arti... @crchum.bsky.social @theneuro.bsky.social
sciencedirect.com
“Earning Its Place: AI in Healthcare,” my keynote at AI26 — the Lamarr Institute Conference in Bonn earlier this week. AI should enter healthcare not by hype but by improving what matters for patients and health systems: access, quality, equity, and the patient experience. @crchum.bsky.social
Building more institutional partnerships is one of my top priorities for @crchum.bsky.social. This week, we signed a new partnership with Lamarr Institute around the hard, real-world questions of AI in healthcare. The goal is not more automated healthcare-it's better healthcare. Stay tuned.
Congrats to @maxlevinson.bsky.social for pulling this off in the middle of 2020's lockdown and the shortage of liquid helium in 🇨🇦. Grateful to our 🇬🇧 colleagues who saved us with grace and wit and more.
Max Levinson@maxlevinson.bsky.social · 3mo agoNEW PAPER🚨👀 in Science Advances with a wonderful transatlantic team. (incl @sylvainbaillet.bsky.social @olejensen.bsky.social @katduecker.bsky.social) Using human MEG, we found lower-order and higher-order neural processes that underlie illusory transitions in conscious visual perception. 🧵👇
Latest collab paper — 🚶♂️🧠 Grateful for the opportunity to contribute, Dr Lamontagne! www.sciencedirect.com/science/arti...
The effects of time constraints on electrocortical dynamics underlying obstacle avoidance while walking
A growing body of literature has characterized the extensive and widespread engagement of cortical resources during the execution of locomotor adaptat…
sciencedirect.com
Congratulations to Dr. Lindsey Power for leading this important review and practical guide to publication 🎯👇.
Imaging Neuroscience@imagingneurosci.bsky.social · 3mo agoNew paper in Imaging Neuroscience by Lindsey Power, Sylvain Baillet, et al: A neuroscientist’s guide to neural burst detection doi.org/10.1162/IMAG...
Des résultats FRQS solides à tous les niveaux (J1, J2, sénior) au @crchum.bsky.social: bravo aux 13 lauréats & lauréates de bourses salariales (65% de succès)! @santepublique-udem.bsky.social @facmed-umontreal.bsky.social @umontreal.ca
Please RB - 🚨We’re hiring @crchum.bsky.social @umontreal-en.bsky.social — Professor, Emerging Viral Threats. DM for more info.
🚨 Hierarchical Flows of Human Cortical Activity. "Cortical flow" is hierarchically organized: slower activity is more upstream, faster beta is more downstream. This asymmetry is emphasized with age. 👉the paper's here: www.biorxiv.org/content/10.6...
Something is emerging in Santiago this July. A new kind of scientific gathering. Open data. Interdisciplinary teams. A shared question that's been challenging researchers for decades. Introducing Consciousness Commons: A satellite workshop for early-career researchers @assc2026.bsky.social #ASSC29
🚨Our new preprint, driven by @xiaoboliu.bsky.social and @alexwiesman.bsky.social. @theneuro.bsky.social @crchum.bsky.social
Earl K. Miller@earlkmiller.bsky.social · 5mo agoCortical rhythmic dynamics for feed forward and feedback signaling. Beta was associated with feedback, consistent with it role in top-down control. Hierarchical Flows of Human Cortical Activity doi.org/10.64898/202... #neuroscience
Exciting news from the chairs of Biomag 2026, Prof. Jiahong Gao and Prof. Huan Luo — the conference website is now live: biomag2026.scimeeting.cn The meetings take place in Beijing, 23–25 August 2026. Save the date and start thinking about ideas for posters and symposia! Please share with colleagues
BIOMAG 2025，在线会议，会议直播平台，网络会议直播，美迪康会务通，学术会议管理系统，会议活动管理，注册签到管理，会场幻灯片传输转播，PPT传输，会议网络直播，电子壁报管理系统，医学会，会员管理系统
biomag2026.scimeeting.cn
🚨A busy start of the year for the lab, with another preprint just out in PsyArXiv, with @lenapl.bsky.social's group. Fernando Gonzales Aste goes deep into the potential for neurophys brain imaging with MEG in severe mental illness research & transformation of care. osf.io/preprints/ps...
🚨new lab preprint; brain fingerprinting entirely revisited: Can we differentiate individuals from just seconds of neurophysiological recordings with machine learning, without resorting to black-box approaches? In this work, Maxence Lapatrie says 'yes'. www.biorxiv.org/content/10.6...
💡 Job opp, please repost! How does Director Innovation & Partnership @crchum.bsky.social sound to you? This is a great moment to join a powerful ecosystem at a moment of transition & acceleration in that core mission. DM if interested & for more info. French language proficiency required.
🍾 First published work of 2026 from the lab. Congrats to recently graduated Dr Niloofar Gharesi on her study of reward prediction error processes under the co-supervision of Prof John Kalaska at @umontreal-en.bsky.social. www.biorxiv.org/content/10.6... @crchum.bsky.social & @theneuro.bsky.social
Neural Signatures of Post-Decision Outcome Expectation and Evaluation in Human Sensorimotor Choice Behavior
The concept of embodied sensorimotor decision-making proposes that processes implicated in evaluating sensory inputs and selecting appropriate motor actions unfold partly in cortical regions traditionally associated with movement planning and execution. Reinforcement learning models emphasize the role of reward prediction error (RPE) in optimizing action selection based on decision outcome feedback. However, most evidence for the existence of RPE signals locates them in midline frontal and parietal cortex, and comes from tasks with externally manipulated reward probabilities that create artificial prediction errors. Whether RPE signals are expressed in human cortical motor areas during deterministic (non-probabilistic) tasks remains unclear, and would provide further support for embodied decision-making. We used magnetoencephalography (MEG) to study post-decision neural dynamics in a color discrimination task in selected cortical regions of interest (ROIs). Participants had to press buttons with their left or right index finger in response to checkerboard stimuli with different levels of color evidence for the correct choice. Outcomes were fully determined by participants' choices. Delayed auditory feedback veridically indicated whether their hand choice was correct or not. We observed a robust beta-band (15-29 Hz) rebound after correct outcome feedback, strongest in ventral and dorsal premotor, anterior cingulate and superior parietal ROIs as well as occipital and auditory ROIs, and weakest in the primary motor and somatosensory ROIs. Critically, the rebound magnitude after correct feedback scaled inversely with color evidence strength and associated decision error rates. It was minimal in strong-evidence trials (~0.1% errors) and maximal in weak-evidence trials (~34% errors), resembling a context-sensitive positive RPE signal that was strongest when a correct outcome was least expected. Alpha-band (8-12 Hz) post-feedback rebound increases in weak evidence trials were not as strong as in the beta band and appeared mainly in occipital, superior parietal and posterior cingulate ROIs. After the decision but before feedback, both beta and alpha band power showed sensitivity to the level of sensory evidence on which the decisions had been based, with reduced post-movement rebound or enhanced suppression in trials with weak evidence, suggestive of internally generated outcome expectations. Pre-feedback alpha rebound suppression was strongest in occipital, superior parietal and posterior cingulate ROIs. Pre-feedback beta rebound suppression was not as strong. Together, these findings reveal distinct beta- and alpha-band dynamics that reflect internal pre-feedback outcome expectations and feedback-driven RPE-like outcome assessments. They support distributed cortical mechanisms, including premotor, parietal and cingulate regions, in reward expectation, outcome evaluation, and adaptive control, highlighting a role for motor and associative cortices in embodied decision-making, performance monitoring, and flexible behavior under uncertainty. ### Competing Interest Statement The authors have declared no competing interest. Fonds de recherche du Québec, https://ror.org/00w3qhf76, FRQ 318042, DOI: https://doi.org/10.69777/318042 NSERC-CREATE: Complex Dynamics of Brain and Behaviour program Canadian Institutes of Health Research, https://ror.org/01gavpb45, CIHR MOP-97944, MOP-142220 [J.K., S.B.]
biorxiv.org
🌟🫱🏼🫲🏻Join the fun & scientific excellence of Montreal and become a primary partner of Centre de recherche du CHUM (CRCHUM) [please repost]. www.nature.com/naturecareer...
Scientific Director - Biomedical Research Institute in Montreal, Canada - Montréal, Quebec (CA) job with Centre d'innovation biomédicale - Université de Montréal | 12851492
The Courtois Institute for Biomedical Innovation (CI²B) is seeking a distinguished scientist to steer its development.
nature.com
Thank you to @aaas.org for the opportunity to lead a new editorial pod at Science Advances on Systems, Computational, Neuro-AI & Neurotechnology (SCANN). Top opportunity to highlight outstanding work at the intersection of neuroscience, computation, and emerging technologies. Send your papers now!
Very proud to announce that the final chapter of my thesis is now out in Cell Reports! How do neurophysiological traits that characterize individuals evolve across the lifespan? We combined data from over 1,000 individuals aged 4–89 to answer this question. (1/6) 🧠👶👦👧👱👩🦱🧔♂️🧓👴 doi.org/10.1016/j.ce...
Redirecting
doi.org
New paper out today in @cp-cellreports.bsky.social !
Jason da Silva Castanheira@jasondasilvac.bsky.social · 8mo agoVery proud to announce that the final chapter of my thesis is now out in Cell Reports! How do neurophysiological traits that characterize individuals evolve across the lifespan? We combined data from over 1,000 individuals aged 4–89 to answer this question. (1/6) 🧠👶👦👧👱👩🦱🧔♂️🧓👴 doi.org/10.1016/j.ce...
-- A lot of brains and one big heart tonight at the farewell-to-2025 party of @crchum.bsky.social. See you in 2026 as we continue moving the lines across the full continuum: research, innovation, better care, and a knowledge-driven, healthier society!
Please repost: another kind of Black-Friday deal!
1) We’re ready ; 2) we’re equipped ; 3) we’re happy. The Royal Society of Canada | La Société royale du Canada induction ceremony. Grateful 🙏: family, trainees, colleagues, 🇨🇦, @mcgill.ca and now @crchum.bsky.social (CRCHUM) et @facmed-umontreal.bsky.social.
🚨New review paper ! Lovely to reconnect with Sheraz Khan around what we think is a timely review of the state of knowledge about brain electrophysiological markers of early/late Alzheimer’s disease pathophysiology, and what's left to discover. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Tracking electrophysiological signatures of Alzheimer's disease: a systematic review of multimodal studies
We conducted a review of the electrophysiological manifestations of Alzheimer's disease (AD) as captured by electroencephalography (EEG) and magnetoencephalography (MEG), with a focus on tracking th...
alz-journals.onlinelibrary.wiley.com
New pain research study in collaboration with @clevelandclinic.bsky.social 👇. — Altered cortical alpha modulations and connectivity in complex regional pain syndrome www.sciencedirect.com/science/arti...
Altered cortical alpha modulations and connectivity in complex regional pain syndrome
Chronic pain alters resting-state cerebral alpha rhythms (8–12 Hz), including whole-brain slowing of peak alpha frequency (PAF). Nevertheless, how the…
sciencedirect.com
This morning, Dr. Drew Weissman delivered an inspiring talk at @crchum.bsky.social, emphasizing the importance of continued curiosity and purpose. 🙏
