🔬 Explore advances in #cycloaddition chemistry through ketenimine #DielsAlder reactivity, in a Perspective by Liss & Newton📚, highlighting heteroatom-containing cycloaddition partners inspired by #ketene chemistry and their potential as highly reactive aza-dienophiles🧪 👉 buff.ly/cbeFYWo

Explore a convergent synthetic strategy toward methyl peracetyl hikosaminide, reported by Fujino & Inoue📚, featuring radical–radical #CrossCoupling and a redesigned intermolecular radical addition to aldehydes that improves selectivity and efficiency🚀 #hikizimycin 👉 buff.ly/tJTRlDy

#Azides meet #enolates! Li & Furkert introduce a straightforward method to form novel #triazenes via nucleophilic addition and electrophilic trapping✨ #cycloaddition 👉 buff.ly/jbfWBEg

👋 Meet the team behind SYNLETT Today we're introducing Rubén Martín, Associate Editor✨ A leader in #CrossCoupling chemistry, metal catalysis, and C–C bond activation at ICIQ, his research is expanding the frontiers of organic synthesis 🧪 Who's next? Next editor in 2 weeks! buff.ly/keEY1uU

Kenta Tanaka & co-workers review recent advances in #sulfur containing salt-based organophotoredox catalysts, highlighting their strong oxidative power and broad reactivity in reductive quenching cycles🧪 #thioxanthylium 👉 buff.ly/lu0J6ee

Dual #functionalization unlocked! Yoichi M. A. Yamada & co-workers report a visible-light #photocatalytic trifluoromethyl carboxylation of #enamides using CF₃SO₂Na and CO₂ 🧪🌿 #radical #trifluoromethylation 👉 buff.ly/VukniiE

Expanding C(sp³) incorporation via #cobalt #catalysis! This Account by L. Reginald Mills & co-workers highlights #Negishi C(sp²)–C(sp³) #CrossCoupling of redox-active alkyl electrophiles, enabling access to pharmaceutically relevant scaffolds🌿 👉 buff.ly/DPOdNSy

From reactive to controllable⚡Dawson Konowalchuk & co-workers introduce an iterative #functionalization approach for heavily substituted cyclobutenes, enabling selective #SuzukiMiyaura arylation of strained rings🧪 #CrossCoupling 👉 buff.ly/aTjB1et

#Gold catalysis meets peptide-based #organocatalysis! Zhou, Wang & co-workers develop a relay catalytic system for the enantioselective synthesis of chiral #azepines via a cascade 1-aza-Cope rearrangement ✨ #PBPS 👉 buff.ly/4tCwHP8

New access to unsymmetrical 2-azapyrenes⚗️ Langer & co-workers report a Brønsted acid–mediated alkyne–carbonyl #metathesis strategy to build these previously unknown polycyclic scaffolds✨ #palladium #CrossCoupling 👉 buff.ly/IljnmuF

New bioinspired route to C- #glycosides 🍬 Sun & He report a protecting-group-free strategy combining the #Petasis (borono–Mannich) reaction with SN2-type deaminative cyclization to directly transform unprotected aldoses into stereoselective C-glycosides🔬 👉 buff.ly/zJ6PQL3

From computation to catalyst discovery! Mita & co-workers combine photoexcited Pd catalysis with #VLAS to identify ligands that suppress back-electron transfer and enable alkyl ketyl #radical formation🧪 #palladium #ketones 👉 buff.ly/LegbZww

👋Meet the team behind SYNLETT Today we're introducing Debabrata Maiti @debabratamaiti.bsky.social, Editor-in-Chief✨ A pioneer in C–H functionalization at IIT Bombay, his research is advancing sustainable synthetic methodologies 🧪Who's next? Next editor in 2 weeks! buff.ly/keEY1uU #MeetTheEditors

New NMR approach for complex fluorinated systems🔬 David Nicewicz & co-workers use J-resolved 2D #NMR with shaped pulse broadband ¹⁹F decoupling to clearly resolve ¹³C–¹⁹F coupling patterns—even up to 274 Hz📊 A powerful way to visualize challenging polyfluorinated compounds. 👉 buff.ly/2CVD7Ng

🧪An overlooked gem in synthesis? Qian & Gui highlight the untapped potential of #sitolactone —a cheap, commercially available chiral building block with major promise for natural product synthesis🌿 Despite its value, it has featured in only a handful of #TotalSynthesis 👉 buff.ly/ppWNWYK

Divergent synthesis made simple🔬 Lei, Huang & co-workers demonstrate that #solvent choice alone can control the formation of α- or β-amino acids in a #rhodium catalyzed reaction🧪 A powerful strategy for efficient access to valuable bioactive compounds. 👉 buff.ly/pMA9Omq

🏆Congratulations to the winners of the #SYNLETT Best Paper Award!🎉 Usui, Hirai co-workers developed a photoredox/Ni dual-catalyzed method for the highly α-stereoselective synthesis of C-aryl glycosides, offering a straightforward route to valuable bioactive scaffolds. 👉 buff.ly/thtu9WX

Our latest article published in @synlettjournal.bsky.social 🎉where We report a sustainable, hydrogel-supported Ag NP catalyst for rapid nitroarene reduction in water under ambient conditions, affording valuable aryl amines. Congratulations Damini👏. Article Link: doi.org/10.1055/a-28...

Efficient route to #alkaloids! Villalgordo & co-workers report a practical, high-yield synthesis of enantiopure anatabine & anabasine using diastereoselective #indium mediated #allylation, followed by ring-closing metathesis and mild chiral auxiliary removal🔁 👉 buff.ly/3kwocUr

Don't miss our Thieme #Cheminar! We're featuring an exciting lineup of Thieme Chemistry Best Paper Awardees🏆 • Prof. Samer Gnaim (Israel) • Prof. Go Hirai (Japan) • Dr. David Palomas @davidpalomas.bsky.social (UK) 📅 June 24, 2026 | 2 PM CEST Register now👉 buff.ly/m34vg9u

#Copper catalysis is advancing modern synthesis! Diaz & Chan report key progress in Cu-mediated unactivated C(sp³)–H #halogenation, powered by radical chemistry, #HAT processes & Cu(I)/Cu(II)/Cu(III) redox cycling 🔬🚀 👉 buff.ly/mgLQA2P

Zhou & Paradies demonstrate #phosphorus PIII/PV=O redox cycling for nonmetal, low-temperature N₂O activation🔬 Addressing a potent greenhouse gas linked to #ozone depletion🌫️ #organocatalysis 👉 buff.ly/KZKYcUq

Unlocking #selenium radical catalysis with dicationic diselenides by Jérémy Merad & co-workers⚗️ Dicationic diselenides act as reservoirs of open-shell organocatalysts, enabling controllable #radical generation 🔬 #photochemistry 👉 buff.ly/mx8Jm3m

Don't miss our Thieme #Cheminar! We're featuring an exciting lineup of Thieme Chemistry Best Paper Awardees🏆 • Prof. Samer Gnaim (Israel) • Prof. Go Hirai (Japan) • Dr. David Palomas @davidpalomas.bsky.social (UK) 📅 June 24, 2026 | 2 PM CEST Register now👉 buff.ly/m34vg9u

Building fused aromatics with alkyne–enone chemistry by Rajai-Daryasarei, Saeed Balalaie & co-workers✨ #Ynenones, formed via #Sonogashira coupling + condensation, serve as versatile reactive platforms🔬 #alkynes 👉 buff.ly/yHAnXVK

⚗️Turning stable #sulfonamides into valuable sulfonyl #fluorides! Yoshino, Matsunaga & co-workers report a one-pot strategy using Me-λ3-iodane activation and Et₃N·3HF for efficient fluoride incorporation🧪 #fluorination 👉 buff.ly/xMoIBsc

Benzylic C–H #functionalization continues to reshape modern synthesis! Ganesh Pandey & co-workers highlight advances in transition-metal catalysis, #photoredox, and radical strategies for selective C–C and C–X bond formation⚗️ 👉 www.thieme-connect.com/products/ejo...

Exciting advances in asymmetric #catalysis by Qiuling Song & co-workers✨ Discover a Ni-catalyzed arylboration of 1,3-cyclohexadienes delivering chiral boronated 1,4-cis- #cyclohexenes with outstanding regio-, enantio-, and diastereoselectivity🚀 #nickel #boration 👉 buff.ly/Wg5CUn8

A new twist in #borylation chemistry✨ Lin & Quan showcase a copper-catalyzed aldehydic C–H borylation using a novel sp²–sp³ diboron reagent (LBH₂–Bpin)🔬 A streamlined route to diverse acylboranes—key intermediates in medicinal chemistry🧬 #boron 👉 buff.ly/hSIEeG8

In this letter by Jessica Budwitz & Christopher Newton, stable #dienes unlock rapid access to #quinones 🧪 Bench-stable thiophenes enable #DielsAlder reactions with arynes, delivering naphthoquinones & anthraquinones in just 2 steps🔬 👉 buff.ly/CVzHHa8