In a small cohort of hospitalized, moderately to severely immunocompromised patients with COVID-19, ensitrelvir was associated with low 28-day mortality, with outcomes comparable to remdesivir. Larger prospective studies are needed. journals.sagepub.com/doi/full/10....

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Adjunctive corticosteroids in non-HIV PJP remain controversial. This systematic review & meta-analysis suggests the highest-quality evidence comes from the lone RCT, supporting benefit in severe disease while underscoring the need for more trials. journals.sagepub.com/doi/full/10....

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Among PLHIV with virologic failure in North-Eastern Uganda, 18.7% had dolutegravir resistance. Poor adherence, NRTI resistance, longer DTG use, and substance abuse were key risk factors. journals.sagepub.com/doi/full/10....

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How should infectious diseases specialists use general-purpose LLMs safely and responsibly? This protocol outlines expert consensus on the principles, opportunities, limitations, and stewardship considerations for LLM use in clinical microbiology and ID. journals.sagepub.com/doi/full/10....

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Magnusiomyces clavatus is an emerging cause of invasive fungal infection in immunocompromised patients. This case reports successful treatment of pediatric M. clavatus fungemia journals.sagepub.com/doi/full/10....

Magnusiomyces clavatus fungemia treated with combination antifungals including isavuconazole in an immunocompromised pediatric patient: a case report - Amanda Z. McPherson, Matthew Miller, Kacie Rytle...

Magnusiomyces clavatus, formerly Saprochaete clavata or Geotrichum clavatum, is an ascomycetous yeast found in the environment as well as the gastrointestinal a...

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Case report describes a 9-year-old girl with severe malnutrition who developed biliary obstruction, pancreatitis, and cholestasis due to Fasciola spp., with concurrent Ascaris lumbricoides infection journals.sagepub.com/doi/full/10....

Chronic Fasciola hepatica infection in a patient with cutaneous visceral loxoscelism: paediatric case report - Blanca Salazar-Mesones, Laura Melissa Mori-Llontop, Alfredo Chiappe-Gonzalez, Claudia Laz...

We present the case of a 9-year-old girl from the Peruvian Andean Region (Ancash), diagnosed with fascioliasis, who was also suffering from severe malnutrition....

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Analysis of 67,134 children from 11 sub-Saharan African countries found that 31% of children under 5 experienced acute respiratory infections. Wasting, air pollution increased prevalence.Wealth, health delivery, media were associated with lower prevalence. journals.sagepub.com/doi/full/10....

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A study from Uganda found 12.6% HCV seroprevalence among patients with sickle cell disease, most of whom had a history of blood transfusion. highlights the need for HCV screening, improved linkage to care, and continued strengthening of transfusion safety. journals.sagepub.com/doi/full/10....

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The Asian tiger mosquito (Aedes albopictus) continues to expand its footprint. New findings from Magdalena, Colombia underscore why ongoing vector surveillance is essential to detect emerging risks for dengue and other arboviral diseases. 🦟🌎 journals.sagepub.com/doi/full/10....

Aedes albopictus in the department of Magdalena, Colombia: spread to the northernmost of the country and implications for arboviral disease transmission - Erik Perdomo-Balaguera, Katiuska Ariza-Campo,...

Background: Aedes albopictus is widely distributed throughout the world. It was introduced into the Americas in 1985 and has been incriminated as secondary vec...

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New data on aortic endograft infection: among 46 patients,63% presented late, S. aureus was the leading cause,blood cultures +Ve in just 54%.Surgical & medical Rx had similar overall success, but medical therapy alone was associated with more relapses. journals.sagepub.com/doi/full/10....

Clinical presentation, management, and outcomes of aortic endograft infections: a retrospective descriptive study - Haitham Alaithan, Sarwat Khalil, Gustavo Oderich, Larry M. Baddour, Muhammad Rizwan ...

Background: Aortic endograft infection (AEGI) is a rare complication of abdominal endovascular aortic repair (EVAR) and thoracic endovascular aortic repair (TEV...

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What is driving the evolving HIV epidemic in Bangladesh? This review synthesizes a decade of evidence on epidemiology, prevention, treatment, and structural barriers to inform the path forward. journals.sagepub.com/doi/full/10....

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Why do some people develop TB while others don't or respond differently to treatment? This pilot study from Panama suggests that host genetics, specifically the VDR BsmI polymorphism, may influence vitamin D status and immune responses in pulmonary TB. journals.sagepub.com/doi/full/10....

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Can we predict which liver transplant recipients will develop early intra-abdominal infections? Cao et al. developed and externally validated interpretable ML models (LIFT) that outperformed MELD and CTP scores, enabling personalized risk stratification journals.sagepub.com/doi/full/10....

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🚀📈New milestone! Excited to share that our Journal Impact Factor has risen to 3.8🎉This achievement reflects the contributions of our authors,reviewers,editors,&readers. Thanks for being part of our community! We look forward to advancing ID through impactful research✨

New nationwide data from Belize show a concerning AMR burden: 41.5% of urinary Enterobacterales isolates were resistant to both ciprofloxacin and TMP-SMX, with high MDR rates even in outpatients. journals.sagepub.com/doi/full/10....

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Persistent pneumothorax in pulmonary TB doesn't always require surgery. In a patient with extensive TB and severe HBV flare, tailored medical management led to complete resolution and recovery. Read more @ journals.sagepub.com/doi/full/10....

Secondary spontaneous pneumothorax due to extensive pulmonary tuberculosis in a patient with acute hepatitis B flare: clinical challenges and therapeutic decision making—a case report - Loi Trinh Duc,...

Secondary spontaneous pneumothorax (SSP), particularly when complicated by a persistent air leak, is an uncommon but serious manifestation of active pulmonary t...

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Persistent pneumothorax in pulmonary TB doesn't always require surgery. In a patient with extensive TB and severe HBV flare, tailored medical management led to complete resolution and recovery. Read more @ journals.sagepub.com/doi/full/10....

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Geospatial targeting of TB screening in Uganda reduced screening volume by 92%, increased TB yield by 10%, and cut costs by >90%. Surveillance data can help find more TB with fewer resources journals.sagepub.com/doi/full/10....

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Neonatal sepsis remains alarmingly common in Ethiopia: pooled prevalence 29.9%, with 66.2% multidrug resistance. Klebsiella pneumoniae and E. coli predominated, showing high resistance to first-line antibiotics. journals.sagepub.com/doi/full/10....

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Adult HBV vaccination decisions are shaped not only by access barriers, but also by culturally embedded beliefs. Context-sensitive education + provider recommendations are key journals.sagepub.com/doi/full/10....

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Do all patients with CIED infection need prolonged antibiotics? In this cohort, ≤2 weeks of therapy AFTER device extra extraction had similar mortality and recurrence rates compared with longer courses after complete device removal. journals.sagepub.com/doi/full/10....

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Late-onset CMV pneumonia can occur even 1 year after auto-HSCT, particularly in patients with profound CD4 lymphopenia. This case highlights the value of immune-guided surveillance and BALF mNGS in diagnosing complex infections in immunocompromised hosts. journals.sagepub.com/doi/full/10....

Scrofuloderma can mimic hidradenitis suppurativa and other chronic skin diseases. This case highlights the need to consider TB in atypical recurrent skin lesions journals.sagepub.com/doi/full/10....

Cutaneous tuberculosis with features suggestive of scrofuloderma masquerading as hidradenitis suppurativa: a case report - Midhun Raj, Tarun Kumar Suvvari, Vimal Thomas, Anand Krishnan R. G., Aishwary...

Scrofuloderma is a form of cutaneous tuberculosis that results from the spread of infection from an underlying focus, most commonly lymph nodes or bone, to the ...

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Among graduating healthcare students at Debre Tabor University: 💊 68% bought antibiotics without a prescription 🧠 Only 32.5% recognized antimicrobial stewardship (AMS) Knowledge alone isn’t enough journals.sagepub.com/doi/full/10....

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In a cohort from Gulu City, 45.4% experienced viral non-suppression, driven by poor ART adherence, delayed HIV disclosure, advanced disease, young age, and economic hardship. journals.sagepub.com/doi/full/10....

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New systematic review & meta-analysis in SSA HCWs shows moderate AMR knowledge (65%) and attitudes (69%), but weaker practices (54%), with a clear knowledge–practice gap—most evident among doctors (knowledge 65%, practice 43%). journals.sagepub.com/doi/full/10....

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TB treatment is evolving—but persistence remains a major barrier. New evidence shows macrophage metabolism and redox state shape intracellular drug tolerance in Mtb. Host-directed strategies may enhance antibiotic efficacy and help shorten therapy ⏳ journals.sagepub.com/doi/full/10....

Targeting macrophage metabolic checkpoints: a host-directed strategy to overcome drug tolerance in tuberculosis - Tarun Kumar Suvvari, Sridhar V. N. S. Kocharlakota, Venkataramana Kandi, 2026

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Case report: a young patient with years of “chronic lung disease” ultimately diagnosed with aggressive HTLV-1 driven lymphoma-fatal within weeks. Early biopsy + T-cell panel (CD4+CD25+ with CD7 loss) should trigger HTLV-1 testing, regardless of geography. journals.sagepub.com/doi/full/10....

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CKD and UTIs form a vicious cycle: kidney dysfunction increases infection risk ; while recurrent UTIs accelerate renal decline. Breaking this loop demands early CKD detection, antimicrobial stewardship & non-antibiotic prevention strategies. journals.sagepub.com/doi/full/10....

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Neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) are valuable, readily available markers for gauging severity in community-acquired pneumonia 🦠📊 journals.sagepub.com/doi/10.1177/...

Assessing pneumonia severity using neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios: a cross-sectional comparison with CURB-65 score - Muhammad Osama, Ahmad Iftikhar, Mallahat Abdul Baseer, ...

Background: Community-acquired pneumonia continues to be a leading cause of morbidity and mortality worldwide. Several validated scoring systems are available f...

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