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Where cellular garbage needs to be removed, there’s always a macrophage happy to take care of it. And where there’s a macrophage… there’s Magda from Immuknowledge, happy to tell you some immunology! 💙 This week, for the tenth Immuknowledge celebration, we dive into microglia–astrocyte crosstalk 🧠

🩸 Mice that get a period? It’s real! 🧬 Scientists have engineered lab mice that can simulate menstruation-like bleeding! This breakthrough opens new pathways for studying menstrual health, disorders like endometriosis, and more! 🧪 🔗Don’t miss the preprint: www.biorxiv.org/content/10.1...

Induction of menstruation in mice reveals the regulation of menstrual shedding

During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

biorxiv.org

🤔A new study challenges a Nobel Prize idea? 🧫Scientists engineered human olfactory receptors and revealed that certain odors can be recognized by single, highly specific receptors, challenging the view that odor perception always relies on broad combinatorial patterns! www.cell.com/current-biol...

Decoding human olfaction by high heterologous expression of odorant receptors detecting signature odorants

Emter et al. improve in vitro expression of odorant receptors (OR) by engineering the C-terminal domain. With a library of engineered ORs, they discover ORs for signature odorants, which they relate t...

cell.com

Regulatory T cells are definitely the stars this week! ✨ First, winning the Nobel Prize, and now starring in the newest episode of Immuknowledge! 🧬What if we told you that some of the things we inherit don’t actually come from our genes? 👀 Don’t miss this episode to find out more!

📊 Presenting data is an inevitable yet demanding part of being a scientist. But perhaps even harder is explaining science to those who are not scientists. So how can complex research be conveyed in a way that non-scientists can easily understand? 🤔

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🩸 One drop is all it takes… And this is another Stem Press episode! 🧪 A recent study demonstrates a small-molecule-only reprogramming strategy that converts human peripheral or cord blood cells into induced pluripotent stem cells (hCiPSCs) with unprecedented efficiency 💯.

💬 Advice Every Student Should Hear 🙌 Dr. Erika Moore reminds us that success doesn’t mean never struggling; it means knowing who can support you and how to get there together. 🤝 Advocate for yourself, build your support network, and most importantly: believe in yourself!

🦷✨ Needles? Nah. Just floss. Scientists have found a wild way to deliver vaccines—using dental floss coated in vaccine ingredients. The study shows that flossing the space between your teeth and gums triggers a powerful immune response—with fewer barriers than under‑tongue drops or nasal sprays.

🧪We all care about our buddies - and so do cells! 🙌 📄This fascinating paper shows how cells with DNA damage caused by radiation don't just deal with it alone. They send out exosomes to nearby bystander cells, helping them respond to DNA damage too! 👇

💡We have already shared many brilliant insights from Dr. McEver, but today we’re sharing one of our personal favorites: ✨“A good mentor has to have a genuine interest in the welfare and the progress of their trainees.”✨