@taylashakespeare.bsky.social

Our paper is now featured in focal plane! Check it out if you're looking for a platform to predict and plan imaging experiments before entering the microscope room! Very proud to be a part of this project - biggest congratulations to the team @henriqueslab.bsky.social who made this happen 🔬🛠️

FocalPlane @focalplane.bsky.social · 4w ago

🔬🔦In our latest Imaging spotlight, Damián Martinez, Bruno Saraiva, @taylashakespeare.bsky.social @mariodelr.bsky.social & @henriqueslab.bsky.social introduce VLab4Mic, an open-source platform that allows researchers to optimise microscopy experiments before performing them.

🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars Damián Martínez & Bruno Saraiva, inaugural preprint of @mariodelr.bsky.social new lab www.biorxiv.org/content/10.6...

Mario Del Rosario@mariodelr.bsky.social · 2mo ago

Congratulations to Damián Martinez, Bruno Saraiva, @taylashakespeare.bsky.social, @wmarkbates.bsky.social, Dylan Owen, @christlet.bsky.social and @henriqueslab.bsky.social We hope VLab4Mic helps researchers design better experiments and ask better biological questions 💻 vlab4mic.henriqueslab.org

Really proud to had the opportunity to contribute to this fantastic work from @taylashakespeare.bsky.social @rajseehra.bsky.social and all the other authors that I cannot find on this platform. Amazing @ijayas.bsky.social !

Izzy Jayasinghe@ijayas.bsky.social · 5mo ago

🚨New paper out today in @acs.org ACS Nano, showing how expansion microscopy can visually quantify the cell surface receptor turnover mediated by signalling & receptor organising machineries on the surfaces of endosomes, some of the smallest organelles in cells. 🧪 🔬 1/ pubs.acs.org/doi/10.1021/...

A surface rendered view of an endosome. The endosome surface is rendered in blue with dimples on it. In specific regions of the endosomal surface, clusters of proteins are seen as aggregates of blobs, coloured in yellow and red.

So exciting to see all our hard work published in ACS nano! This paper highlights how we calibrated intrinsic expansion in X10 ExM to investigate the organisation of endosomal nanodomains during EGFR trafficking - check it out! 🔨🔬📄🎉

Izzy Jayasinghe@ijayas.bsky.social · 5mo ago

🚨New paper out today in @acs.org ACS Nano, showing how expansion microscopy can visually quantify the cell surface receptor turnover mediated by signalling & receptor organising machineries on the surfaces of endosomes, some of the smallest organelles in cells. 🧪 🔬 1/ pubs.acs.org/doi/10.1021/...

A surface rendered view of an endosome. The endosome surface is rendered in blue with dimples on it. In specific regions of the endosomal surface, clusters of proteins are seen as aggregates of blobs, coloured in yellow and red.