Thanina

@thancbn.bsky.social

PhD student in computational biology by day, artist by night • 25 • ENG/FR ok :)

just read a paper about how melanoma incidence in grey horses is due to a cnv and 😊 hihi bioinformatians helped answer this question i've been asking myself for 15 years ! ! ! it's such a cool job that we do

How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...

Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics

Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...

doi.org