Shira G-S, PhD

@thehematopoet.bsky.social

Scientist studying chromatin organization in myeloid malignancies in the Tothova Lab at the Dana Farber Cancer Institute 👩‍🔬 she/her

Just getting home after an incredible week at FASEB hematologic malignancies. This is truly the best meeting and I feel so lucky to be able to attend!! The week was too busy to actively post so here’s a little recap thread… #HEMSRC 🩸🔬

So excited to share a pre-print of my thesis work! Check it out to see how we can leverage an epigenetic resistance mechanism to PI3K inhibitors to target leukemic stem cells!! (Spoiler alert: PRC2 is involved!) Really proud of this work conducted with @gritsmanlab.bsky.social

bioRxiv Cancer Bio@biorxiv-cancer.bsky.social · last yr.

Exploiting an Epigenetic Resistance Mechanism to PI3 Kinase Inhibition in Leukemic Stem Cells https://www.biorxiv.org/content/10.1101/2025.07.11.663968v1