What if AI could invent enzymes that nature hasn’t seen? 👩🔬🧑🔬 Introducing 🪩 DISCO: Diffusion for Sequence-structure CO-design 📝 Blog: disco-design.github.io 📄 Paper: arxiv.org/abs/2604.05181 💻 Code: github.com/DISCO-design...
Théophile Lambert
@tlambert99.bsky.social
PhD Candidate in Co-supervision between Université Paris-Saclay and Caltech | Fulbright Scholar | Ecole Normale Supérieure de Lyon
New work in Nature Communications! Using generative AI, we designed TrpB enzymes that are not only functional, but outperform natural ones and rival top lab-evolved TrpBs. www.nature.com/articles/s41... Huge thanks to @francesarnold.bsky.social, @anima-anandkumar.bsky.social, and all co-authors!