Nanoscale DNA tracing reveals the self-organization mechanism of mitotic chromosomes: Cell www.cell.com/cell/fulltex.... Impressive work by former postdoc @kaibeckwith.bsky.social and the @ellenberglab.bsky.social!
Nanoscale DNA tracing reveals the self-organization mechanism of mitotic chromosomes
3D visualization of genomic DNA reveals that the characteristic shape of mitotic chromosomes emerges through extrusion of large genomically overlapping DNA loops and their self-repulsion.
cell.com