Alcohol Intake and Health Study: No Protective Effect at Low Levels, With Mortality Increasing to 1 in 25 at 14 Drinks Per Week - PubMed

Alcohol consumption, including at what may be perceived as "moderate" levels, is associated with increased mortality and morbidity risks. These results support tightening alcohol use guidance in the United States, for both males and females, to no more than 1 drink per day.

pubmed.ncbi.nlm.nih.gov

Examination of psychometric properties of the Posttraumatic Stress Related Functioning Inventory, Revised (PRFI-5) in veterans - PubMed

This study examines a pragmatic measure of PTSD-related psychosocial functioning and highlights the importance of incorporating a measure of psychosocial functioning routinely alongside symptom measures as a component of psychological assessment and practice. (PsycInfo Database Record (c) 2026 APA, …

pubmed.ncbi.nlm.nih.gov

Sex and the clock: Exploring sex differences in chronotype and circadian behavior among healthy older adults - PubMed

This study aimed to compare subjective and objective circadian measures with a focus on sex differences and cognition in healthy older adults. A total of 126 participants (aged 65-90 years) completed the Horne & Ostberg Morning-Eveningness Questionnaire (MEQ) and the Circadian Type Inventory (CT …

pubmed.ncbi.nlm.nih.gov

Associations of dementia polyexposure scores to Alzheimer's disease endophenotypes in diverse populations - PubMed

CRS capture AD-related risk across diverse populations and modestly reflect underlying biological endophenotypes, supporting their utility in community-based risk assessment.

pubmed.ncbi.nlm.nih.gov

Expanding the Digital, Donor-Assisted Conception Tool to Empower Parental Telling and Talking (TELL Tool) Intervention to the Pregnant and Early Parenthood Periods: Findings From a Qualitative Study - PubMed

Findings illustrate the distinct needs and desires of parents-to-be, new parents, and clinicians about providing expanded content for the TELL Tool that is informed by current evidence and end users, ultimately advancing best practices in this area. Future plans include testing the TELL Tool tailore …

pubmed.ncbi.nlm.nih.gov

Urinary cotinine cut-offs for tobacco smoke exposure in pregnancy and associations with child intelligence quotient: A multi-cohort analysis - PubMed

This study provides a novel classification of prenatal tobacco smoke exposures. Although the associations with child IQ were statistically insignificant, the study carries important implications for future research on developmental origins of diseases.

pubmed.ncbi.nlm.nih.gov

I’m a Neurologist. Here’s How to Protect Your Aging Brain

UCSF expert Kristine Yaffe, MD, explores how targeting modifiable risk factors—like sleep and exercise—can actively protect your aging brain.

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The Mediating Role of Alcohol Use Between Adverse Childhood Experiences and Delinquency Among Youth in the Legal System - PubMed

Rates of alcohol use and exposure to adverse childhood experiences (ACEs) are elevated among youth in the legal system (YILS) compared to their non-legally involved peers. Exposure to ACEs has been associated with later alcohol use and delinquency, and YILS often engage in delinquent behavior while …

pubmed.ncbi.nlm.nih.gov

Development of a mandarin version of the five dimensional altered states of consciousness (5D-ASC) rating scale - PubMed

Here, a Mandarin version of the 5D-ASC was developed by a team of highly qualified scientists and translators. Further research is needed to evaluate its reliability and validity in clinical and non-clinical Mandarin-speaking populations.

pubmed.ncbi.nlm.nih.gov

Treatment of Disturbed Sleep in Progressive Supranuclear Palsy: a randomized, remote, double-blinded, 6-week cross-over design study protocol comparing zolpidem, suvorexant, and placebo - PubMed

Treatment of Disturbed Sleep in Progressive Supranuclear Palsy (PSP); NCT04014389. Registered on June 2, 2019.

pubmed.ncbi.nlm.nih.gov

Relationships between heritable dementia risk factors, cardiovascular risk factors in young adulthood, and midlife neuropsychological outcomes - PubMed

BackgroundSelected cardiovascular factors, <i>APOE4</i> carriership, and family history (FH) are robust risk factors for Alzheimer's disease and dementia. While cardiovascular risk tends to affect cognition from midlife, it remains unclear whether heritable risk predicts cardiovascular health in you …

pubmed.ncbi.nlm.nih.gov

I’m a Neurologist. Here’s How to Protect Your Aging Brain

UCSF expert Kristine Yaffe, MD, explores how targeting modifiable risk factors—like sleep and exercise—can actively protect your aging brain.

ow.ly

Sex-specific associations of depression with inflammatory markers: a systematic review and meta-analysis - PubMed

Overall, results indicated modest associations between depression and elevated inflammation in both sexes, with slightly stronger associations in males. Associations between specific inflammatory markers (i.e., IL-6 in females and CRP in males) and subsequent depression differed by sex. These findin …

pubmed.ncbi.nlm.nih.gov

Recentering the Biopsychosocial Model in Psychiatric Training - Academic Psychiatry

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I’m a Neurologist. Here’s How to Protect Your Aging Brain

UCSF expert Kristine Yaffe, MD, explores how targeting modifiable risk factors—like sleep and exercise—can actively protect your aging brain.

ow.ly