Please join us for Adnan Ahmed's workshop "Investigating Global Hepatic Mitochondrial Metabolic Reprogramming During Type 2 Diabetes" on Wednesday, September 16 from 12-1 in 5-669 BSB.

Congratulations to @drishitachandel.bsky.social, recipient of Physiology's High-Impact Research Award! The award recognizes graduate students and postdocs who publish first-author papers in Nature, Science, or Cell. A well-deserved honor following her recent first-author Science paper.

Please join us for Candice Paulsen's seminar "It’s complicated: Mapping the calcium regulation mechanism of a critical pain sensor" on Tuesday, September 15th from 9:30 - 10:30 in 5-669 BSB.

The Hultman Lab is looking for an outstanding post-baccalaureate research intern to support Dr. Hultman's R01, “Investigating single cell transcriptomics and epigenetic regulation to enable stress-resistant brain network activity." Please share broadly. jobs.uiowa.edu/research/vie...

The Physiology graduate students gathered for a social event last week to connect before the start of the semester. A special thanks to Aleigha Gugel, Stephanie Hernandez, and Gabe Prather for organizing the event.

Congratulations to Dr. Stephanie Gantz, her lab, and collaborators on their new publication "Activation of mu-opioid receptors slows pacemaking in hypothalamic A11 dopamine neurons" in Neuropsychopharmacology! Learn more about the publication: www.linkedin.com/feed/update/....

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Congratulations to Dr. Ishita Chandel, Dr. Kevin Campbell, and the Campbell Lab on their new paper in Science! Their discovery uncovers a new way dystroglycan controls its own function, providing important insights into diseases caused by defective dystroglycan activity. doi.org/10.1126/scie...

Xylose phosphatase activity of dystroglycan self-regulates its receptor function

Dystroglycan (DG) is an extracellular matrix receptor crucial for tissue development and pathogen entry. DG harbors a long, complex glycan called matriglycan. Loss of matriglycan or reduction in its length disrupts DG function, causing ...

doi.org

Congratulations to Dr. Mike Anderson, his lab, and collaborators on their new publication in Experimental Eye Research: “C1q dependency of retinal ganglion cell death in blast-mediated traumatic brain injury.” doi.org/10.1016/j.ex...

Congratulations to @organicmechanic.bsky.social, his lab, and collaborators on their new publication in Molecular Psychiatry:“Nonsense-mediated decay influences position-dependent effects of SCN2A premature stop codons on neuronal excitability and behavior.” www.nature.com/articles/s41...

Nonsense-mediated decay influences position-dependent effects of SCN2A premature stop codons on neuronal excitability and behavior - Molecular Psychiatry

Molecular Psychiatry - Nonsense-mediated decay influences position-dependent effects of SCN2A premature stop codons on neuronal excitability and behavior

nature.com

Congratulations to @organicmechanic.bsky.social and his team members Dr. Ahmad Al Saneh and Dr. Lionel Gissot on their new publication in Nucleic Acids Research, "Programmed repair of disease-causing UGA premature termination codons in mammalian brain." 🔗 doi.org/10.1093/nar/...

Congratulations to Dr. Scott Moye-Rowley, his lab, and collaborators on their new publication in Genetics, "Candida glabrata YPK2 is a multidrug susceptibility locus." doi.org/10.1093/gene...

Candida glabrata YPK2 is a multidrug susceptibility locus

Abstract. The biological conservation between fungi and mammals due to a common ancestor has made development of selective antifungal drugs a difficult cha

doi.org

We're excited to celebrate the Year 22 renewal of the Iowa Wellstone Muscular Dystrophy Specialized Research Center! Congratulations to Drs. Kevin Campbell, Katherine Mathews, Steven Moore, and the entire Wellstone team.

What’s better than one major NIH award? Two! 🎉 Congratulations to @alexmsci.bsky.social and her lab on receiving an R01 from the National Institute of Allergy and Infectious Diseases for her project, “Decoding the Structure, Function and Pharmacology of TOK Channels from Human-Pathogenic Fungi.”

Congratulations to Dr. Alex Miller @alexmsci.bsky.social on receiving her first major research grant from the National Institute of General Medical Sciences (NIGMS)! She has been awarded a MIRA R35 for her project, “Dissecting the Molecular Basis of Potassium Homeostasis in Yeast” (R35 GM161440).

We’re excited to share a new PNAS publication from the Campbell Lab. Congratulations to Dr. Kevin Campbell, his lab, and collaborators. www.pnas.org/doi/10.1073/...

Physiology has had two great poster sessions in the last few weeks. Thank you to everyone who presented, attended, and supported these events. We are proud of the creativity, curiosity, and collaboration on display throughout both sessions.

Congratulations to Dr. Rainbo Hultman @brainbolab.bsky.social, her lab, and collaborators on their new publication in The Journal of Headache and Pain: “Early life stress induces brain-wide electrical network predisposition to migraine.” link.springer.com/article/10.1...

Early life stress induces brain-wide electrical network predisposition to migraine - The Journal of Headache and Pain

Background Migraine is a disorder of severe, recurrent headaches and debilitating sensory, cognitive and affective symptoms, often triggered by stress. Early life stress in childhood has been shown to...

link.springer.com

Thank you to everyone who joined us for the 2026 Wellstone Patient and Family Conference! It was wonderful to connect patients, families, researchers, and partners for another meaningful and inspiring gathering. We’re grateful for this community. wellstone.medicine.uiowa.edu

We are pleased to share a new publication from Dr. Kevin Campbell in The Lancet Neurology: “Clinical presentations and pathophysiological mechanisms of dystroglycanopathy: advancing therapeutic strategies.” Read the article: www.thelancet.com/journals/lan...

Clinical presentations and pathophysiological mechanisms of dystroglycanopathy: advancing therapeutic strategies

Dystroglycanopathies are muscular dystrophies with varying clinical severities, ranging from congenital-onset to adult limb-girdle muscular dystrophy. Dystroglycanopathies are caused by a loss of func...

thelancet.com

Read about Dr. Russo and his postdoc Dr. Della Pietra’s latest work exploring progress over the past five years in targeting CGRP pathways—an area that has reshaped how we understand and treat migraine, and where the science is headed next to improve patient outcomes. doi.org/10.1080/1472...

Advances in CGRP therapeutic targets for migraine: where do we stand 5 years later?

The past 5 years of success with calcitonin gene-related peptide (CGRP) based drugs has transformed migraine into a relatively treatable neurological disorder. There are now eight monoclonal antibo...

doi.org

Thank you to our presenters and everyone who came to the poster session to make it a success. Presenters included: Brice Durocher, Gabe Prather, Sneha Singh, Ali Razzaghi, Nick Schnicker, and Shiva Mandala.

Congratulations to Dr. Ayushi Mittal of Dr. Julian Sebag's lab on her successful thesis defense!

Congratulations to Dr. Ahmad Al Saneh of Dr. Chris Ahern's lab on his successful thesis defense!

Congratulations to Dr. Andrew Russo on being selected as the MacDonald Critchley Lecturer at the Migraine Trust International Symposium. Andy will share his latest research on the molecular basis of migraine in Glasgow, UK this September. mtis2026.org

Congratulations to Dr. Scott Moye-Rowley and his lab on their new publication in Methods in Molecular Biology "Electrophoretic Mobility Shift Assay in Aspergillus fumigatus." link.springer.com/protocol/10....

Electrophoretic Mobility Shift Assay in Aspergillus fumigatus

One of the classic techniques to allow detection of direct DNA-binding by sequence-specific transcription factors is the electrophoretic mobility shift assay (EMSA). EMSA takes advantage of the reduce...

link.springer.com

Congratulations to Dr. Nikolai Artemyev and his lab on their new publication in the Journal of Biological Chemistry, "Structural basis of phosphodiesterase-5 conformational organization revealed by a PDE6/PDE5 Chimera." www.sciencedirect.com/science/arti...

Structural basis of phosphodiesterase-5 conformational organization revealed by a PDE6/PDE5 Chimera

Phosphodiesterase 5 (PDE5) plays critical role in the nitric oxide-cGMP signaling pathway. Consequently, PDE5 catalytic site inhibitors are widely use…

sciencedirect.com

Congratulations to Dr. Scott Moye-Rowley, Dr. Mark Stamnes, and staff scientist Dr. Sanjoy Paul on their new publication in Springer Nature "Chromatin Immunoprecipitation in Aspergillus fumigatus." link.springer.com/protocol/10....

Chromatin Immunoprecipitation in Aspergillus fumigatus

Aspergillus fumigatus is the major human filamentous fungal pathogen. While its importance as a pathogen is well-appreciated, our understanding of its biology is still at an early stage. One valuable ...

link.springer.com

We were pleased to welcome Swetha Murthy, PhD, Assistant Professor at OHSU, this past week for a seminar hosted by Dr. Stephanie Gantz and Dr. Alex Miller.

Congratulations to Dr. Alex Miller, her lab, and collaborators on their new publication in Nature Communications "Molecular architecture of the fungal-specific potassium channel TOK1" www.nature.com/articles/s41...

We mourn the loss of our former colleague, Dr. Daryl Granner. Learn more about his storied career and lasting impact here: medicine.uiowa.edu/news/2026/04...