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Ulises Hernández

@uliseshmc.bsky.social

Population genetics University of Arizona PhD Candidate

3 Posts63 Follower 115 Folgt

Joanna Masel @joannamasel.bsky.social · 4mo ago

Our new paper doi.org/10.1098/rspb... on long-term genetic threats to small populations finds that "mutational meltdown" (bad mutations fixing) is less of a problem than "mutational drought" (too few good new mutations) @wmawass.bsky.social @uliseshmc.bsky.social @jeremyjberg.bsky.social 1/5

Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation

Abstract. Habitat loss contributes to extinction risk in multiple ways. Genetically, small populations can face an ‘extinction vortex’—a positive feedback

doi.org

Ulises Hernández @uliseshmc.bsky.social · last yr.

Muy buena oportunidad para estudiantes internacionales interesados en un doctorado en US. eeb.princeton.edu/graduate/eeb...

EEB Scholars Program

The 2024 EEB Scholars Program application is now open and will close on June 15th, 2024.As part of efforts to increase the diversity and accessibility of graduate studies in ecology and evolutionary b...

eeb.princeton.edu

Joanna Masel @joannamasel.bsky.social · 2y ago

Our latest paper revisits Haldane 1957 on speed limits to adaptation, the paper that triggered neutral theory. We clarify and then significantly extend the theory, and apply the resulting model to @mexpositoalonso.bsky.social's data doi.org/10.1093/gene... 1/14

Substitution load revisited: a high proportion of deaths can be selective

Abstract. Haldane's Dilemma refers to the concern that the need for many “selective deaths” to complete a substitution (i.e. selective sweep) creates a spe

doi.org

Lily Roberts @lilyroberts.bsky.social · 2y ago

There are even more direct cuts — because Haskell is run through the federal Bureau of Indian Education, 30% of staff and faculty were let go last night. lawrencekstimes.com/2025/02/14/h...

Haskell Indian Nations University lays off dozens of employees after federal orders

Numerous employees of Haskell Indian Nations University lost their jobs Friday as part of sweeping nationwide cuts ordered by President Donald Trump's administration.

lawrencekstimes.com

PopGen Vienna @popgenviennaphd.bsky.social · 2y ago

The PopGen Vienna Seminar series schedule is ready for the next term (Mar-Jun). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website www.popgen-vienna.at/news/seminars/

PopGen Seminar Series
Summer Term 2025

04.03.25 – Lutz Becks (Univ. of Konstanz, DE) The evolutionary dynamics of novel endosymbiosis.
11.03.25 – Ilkka Kronholm (Univ. of Jyväskylä, FI) How chromatin structure influences genetic and epigenetic variation.
18.03.25 – Katja Hoedjes (Vrije Univ. Amsterdam, NL) Understanding functional impact of genetic variation on complex traits at a single nucleotide resolution.
25.03.25 – Sophie Armitage (Freie Univ. of Berlin, DE) Evolutionary ecology of host-pathogen interactions.
01.04.25 – Matthew Rockman (New York Univ., US) Developmental evolution is a population-genetics problem.
08.04.25 – Wen-Juan Ma (Vrije Univ. Brussels, BE) The evolution of sex chromosomes and sex determination in frogs.
15.04.25 – Almorò Scarpa (Vetmeduni, AT) Two centuries of transposable element invasions in Drosophila melanogaster
22.04.25 – Julia Kreiner (Univ. of Chicago, US) The mode and tempo of genomic adaptation to contemporary agriculture.
29.04.25 – Martin Kaltenpoth (Max Planck Inst. for Chemical Ecology, DE) Microbial symbionts as sources of evolutionary innovations in beetles.
06.05.25 – Luisa Pallares (Friedrich Miescher Laboratory, DE) Phenotypic robustness across the genotype-phenotype map, from genes to environment and back.
13.05.25 – Diana Rennison (Univ. of Calif., San Diego, US) Understanding the predictability of evolutionary trajectories using threespine stickleback.  20.05.25 – Filipa Sousa (Univ. of Vienna, AT) Bioenergetics Evolution: The link between Earth’s and Life’s history.
27.05.25 – Yun Song (Univ. of California, Berkeley, US) Learning and applying complex probability distributions over biological sequences.
03.06.25 – April Wei (Cornell Univ., US) Enabling efficient analysis of biobank-scale data with genotype representation graphs.

ALT TEXT OUT OF SPACE, GO TO https://www.popgen-vienna.at/news/seminars/

Joanna Masel @joannamasel.bsky.social · 2y ago

Our latest paper www.sciencedirect.com/science/arti... shows that mass PCR testing could control a range of potential respiratory pandemics at low societal cost. We also explore logistics. Even a prototype would be really nice now with H5N1. @jameshay.bsky.social 1/9

Enhanced testing can substantially improve defense against several types of respiratory virus pandemic

Mass testing to identify and isolate infected individuals is a promising approach for reducing harm from the next acute respiratory virus pandemic. It…

sciencedirect.com

Walid Mawass @wmawass.bsky.social · 2y ago

🥳My work on the reliability of pedigrees used in quantitative genetic estimations of the genetic basis of phenotypic trait is out now in @jevbio.bsky.social! It also serves as a good intro for the use of pedigrees to infer genetic signals of phenotypes in populations academic.oup.com/jeb/advance-...

Assessing the impact of pedigree attributes on the validity of quantitative genetic parameter estimates

Abstract. Investigating the evolution of complex traits in nature requires accurate assessment of their genetic basis. Quantitative genetic (QG) modeling i

academic.oup.com

Ryan Hernandez @rdhernand.bsky.social · 2y ago

Yesterday, the National Human Genome Research Institute (NHGRI) had an amazing office for Training, Diversity, and Health Equity (TiDHE). Today TiDHE is a 404 - Page Not Found. www.science.org/content/arti...

Ryan Hernandez@rdhernand.bsky.social · 2y ago

It is gut-wrenching to watch this process roll out in real time... If you Google "NIH F99 K00 DSPAN" you will see many links to this program. All of them are dead.

Ulises Hernández @uliseshmc.bsky.social · 2y ago

For those interested in a new academic position (Faculty or Postdoc). This repo has a great variety of options docs.google.com/spreadsheets...

ecoevojobs.net 2024-25

docs.google.com

David Enard @denard.bsky.social · 2y ago

We found high levels of adaptive evolution in genes expressed in barrier tissue immune cells including 🫁, and/or expressed early during immune responses --> host adaptation likely works best when it cuts infections short early, before pathogens reach high numbers. www.nature.com/articles/s41...

Adaptation in human immune cells residing in tissues at the frontline of infections - Nature Communications

Immune cells are under evolutionary pressure due to their anti-infective defence role. Here Salvador-Martínez and Murga-Moreno et al. combine population genetics approaches and Human Cell Atlas data, ...

nature.com

University of Arizona EEB @uofa-eeb.bsky.social · 2y ago

We are excited to announce a tenure track faculty position on the genomics of resilience! Come join us in EEB here in Tucson! More details about the position at the link below. Application review begins on December 9! 🧪 arizona.csod.com/ux/ats/caree...

Assistant Professor, Ecology and Evolutionary Biology

Establish and maintain a competitive research program.Teach at the graduate and undergraduate levels and contribute to mentoring students, including t...

arizona.csod.com

Joanna Masel @joannamasel.bsky.social · 2y ago

Our new preprint changes the way we look at an “extinction vortex” in which a small population loses fitness, causing it to become even smaller. doi.org/10.1101/2024... @wmawass.bsky.social @uliseshmc.bsky.social 1/n

Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation

Natural populations are increasingly at risk of extinction due to climate change and habitat loss and fragmentation. The long-term viability of small populations can be threatened by an extinction vor...

doi.org