Celebrating #InternationalDayOfWomenAndGirlsInScience and the incredible researches in our Drug Discovery Group who design smarter molecules, who unlock new therapeutic opportunities, and who show every day what is possible when talent is empowered and supported. #WomenInSTEM #CancerDrugDiscovery

Proud to be part of such a great team pushing boundaries in drug discovery #WorldCancerDay

CRUK Newcastle Drug Discovery Group@nudrugdiscovery.bsky.social · 7mo ago

Today on #WorldCancerDay we recognise the progress towards better cancer treatments. At the Newcastle Drug Discovery Group we bring together expertise in cancer biology, structural biology and medicinal chemistry to develop novel therapeutic strategies and more precise targeted therapies.

🎓 We have a fully funded PhD opportunity in my lab and the Newcastle Cancer Drug Discovery Group to explore how oncogene-driven replication stress fuels Squamous Cell Carcinomas—and how to target it. #CancerResearch #PhD 📅 Apply by: 4 Dec 2025 🔗 Apply here: www.findaphd.com/phds/project...

MRC DiMeN Doctoral Training Partnership: Targeting oncogene-induced replication stress in squamous cell carcinoma at Newcastle University on FindAPhD.com

PhD Project - MRC DiMeN Doctoral Training Partnership: Targeting oncogene-induced replication stress in squamous cell carcinoma at Newcastle University, listed on FindAPhD.com

findaphd.com

Celebrating #WorldCancerResearchDay with a book & bake sale for CRUK! Great turnout from across labs — including our Drug Discovery group. Love seeing science come together for a cause that drives our work. 🔬 #CancerResearch #CRUK #NUCentreForCancer #CancerDrugDiscovery #KeepScienceCurious

Huge thanks to Caterina Missero for the invitation to Naples and the CEINGE Research Centre! It was a pleasure to talk about our research on cSCC, fibroblasts & senescence. Fantastic to get to know everyone—great discussions, ideas, and scientific exchange. Looking forward to staying in touch!

Wishing everyone a fantastic day at our @mosmedcdt.bsky.social PhD conference!

CRUK Newcastle Drug Discovery Group@nudrugdiscovery.bsky.social · last yr.

We're at @durhamuniversity.bsky.social for Day 1 of the @mosmedcdt.bsky.social Conference! Looking forward to two days of insightful talks and discussions - especially from Drug Discovery researchers - highlighting the breadth of ongoing research across the programme. #mosmed25

Happy International Women's Day! May you all have a fantastic year ahead of you! #Rights #Equality #Empowerment

Thanks to @walkolab.bsky.social for visiting @newcastleuni.bsky.social and sharing their insights into the interactome of YAP/TAZ.

Newcastle University Centre for Cancer@nucancer.bsky.social · last yr.

It was a pleasure hosting @walkolab.bsky.social from the Bart's Centre for Squamous Cancer in our NUCoRE Cancer seminar series this week where he told us about his exciting research on transcriptional addiction.

A year ago I started working with this fantastic group of women in @nudrugdiscovery.bsky.social. It is a privilege to be part of such a hard working, dedicated and inspiring team. #Empower&Inspire #WomenInScience @newcastleuni.bsky.social @nucancer.bsky.social

CRUK Newcastle Drug Discovery Group@nudrugdiscovery.bsky.social · 2y ago

🌍👩‍🔬 Celebrating International Women in Science Day! Thank you to all the women in our drug discovery team, their dedication, innovation and inspiration. Together we are pushing boundaries to discover novel anticancer drugs! @nucancer.bsky.social @crhorizons.bsky.social @newcastleuni.bsky.social

Today is #WorldCancerDay A day to raise awareness for patients and families affected by cancer, but also a day to celebrate and support the scientists & researchers who study cancer and develop novel anticancer therapies @nucancer.bsky.social @nudrugdiscovery.bsky.social

Cancer Research UK@cancerresearchuk.org · 2y ago

In the UK, nearly 1 in 2 people will get cancer in their lifetime. It's World Cancer Day today – a global day to raise awareness and take action against cancer 🌍 Whatever your cancer experience, share this post and help us get the word out. #WorldCancerDay #WCD2025

We have a #PhDstudentship starting in Sept with me and @hannahstewart92.bsky.social ideal for candidates with interest in research in #medicinalchemistry and #organicsynthesis Contact us for more details but apply through the university portal, details in the link: www.ncl.ac.uk/postgraduate...

Read about our potential breakthrough in oncology - restoring wild type p53 function with ASTX295. This molecule was co-developed with Astex Pharmaceuticals, and is currently showing great phase I trial readout! #cancer #medchem #clinicaltrials www.linkedin.com/posts/cancer...

Cancer Research Horizons on LinkedIn: #onmyhorizon #cancerresearch

2024 milestones worth celebrating 🧬🌟 Bravo to the incredible researchers at the Drug Discovery Unit at Newcastle University. They've unlocked a potential…

linkedin.com

Great work from our collaborators @walkolab.bsky.social elucidating the functional interplay of YAP and RIF1 in cutaneous squamous cell carcinoma. #cancerresearch #skincancer

YAP engages RIF1 to dampen replication stress in squamous cell carcinoma.

Squamous cancers are the most frequently diagnosed solid tumours world-wide. The closely related transcriptional co-regulators YAP and TAZ (WWTR1) have emerged as important drivers of tumour initiatio...

biorxiv.org

Walko Lab@walkolab.bsky.social · 2y ago

Goal accomplished! First @walkolab.bsky.social PhD student project published as pre-print on (Austrian) Christmas Day 🥳

Our research is critically dependent on funding we receive from @cancerresearchuk.org and we are also willing to do our bit towards fundraising. In 2024: Funds Raised: £6,440 (+£1,031 gift aid) Online Donations: 283 Events: Great North Run, Race for Life, Shine Walk, Leeds Marathon, bake sale, quiz

Last outing of my Bath lab together with the Walko lab in 2024. 🎄 🥳 Wishing everyone a relaxing break! @walkolab.bsky.social

Exciting collaboration from our @nudrugdiscovery.bsky.social team @newcastleuni.bsky.social, @crhorizons.bsky.social and @diamondlightsource.bsky.social to accelerate hit discovery with structure-based drug design. Big shout out to our structural biology team led by Jane Endicott & Martin Noble!🙌

CRUK Newcastle Drug Discovery Group@nudrugdiscovery.bsky.social · 2y ago

Thrilled to share the new collaboration between @diamondlightsource.bsky.social + @crhorizons.bsky.social + @newcastleuni.bsky.social to accelerate structure-based drug development via fragment screening! More here: bit.ly/4g7Et3f 🧬🧶 #chemsky #chembio We're already hard at work on exciting targets 💪

PhD student Ioanna Kontou is presenting her work on how DNA damaging agents impact fibroblasts and consequently promote cSCC at this year's "Skin @Bath" conference @uniofbath.bsky.social @walkolab.bsky.social

Had a fantastic time at the BACR breast cancer conference, meeting friends and collaborators, and presenting work from former PhD @emilylay.bsky.social #cancerresearch #fibroblasts

CRUK Newcastle Drug Discovery Group@nudrugdiscovery.bsky.social · 2y ago

@utejungwirth.bsky.social and Kleopatra Papa spoke at this week's BACR New Developments in #BreastCancer Research conference, highlighting their work on the effect of chemotherapy on cancer associated fibroblasts and drug resistance 🧫 @nucancer.bsky.social @crhorizons.bsky.social #cancer #cansky

Follow our group also on @nudrugdiscovery.bsky.social We are a team of medicinal chemists, pharmacologists & cancer and structural biologists based at Newcastle University, part of Cancer Research Horizons @crhorizons.bsky.social & the Newcastle University Centre for Cance @nucancer.bsky.social

Thinking of applying to Newcastle for postgraduate study? See details below of an upcoming Postgraduate Virtual Open Day on Wed 27th Nov: www.ncl.ac.uk/study/meet/p...

Postgraduate Virtual Open Day

Explore your postgraduate study options at our Virtual Open Day on Wednesday 27 November. Sign up now.

ncl.ac.uk

Our Newcastle University Centre for Cancer has its own account @nucancer.bsky.social Follow us to hear from our 100+ cancer researchers & how they translate their research into the clinic. For example our Drug Discovery group developed the clinically approved Rucaparib (PARPi) & Erdafitinib (FGFRi)

Love the hashtag #KeepScienceCurious from @helloeacr.bsky.social Such an important message to drive innovation in cancer drug discovery and cancer research. www.linkedin.com/posts/europe...

European Association for Cancer Research (EACR) on LinkedIn: #worldscienceday #keepresearchcurious #cancerresearch

This #WorldScienceDay we're celebrating the crucial role of cancer researchers' curiosity in driving life-saving developments 🤩🙌…

linkedin.com

In October I walked together with colleagues the #NightShineWalk in support of @cancerresearchuk.bsky.social to raise vital funds for cancer research 💙🩵💜 Such a great experience! Thanks to those who supported our fundraising. fundraise.cancerresearchuk.org/team/newcast...

Our methods chapter on cell-derived extracellular matrix and its tumor cell interactions published in Methods in Molecular Biology - Imaging Cell Signaling this year link.springer.com/protocol/10....

Generation of 3D Fibroblast-Derived Extracellular Matrix and Analysis of Tumor Cell-Matrix Interactions and Signaling

Fibroblasts are the major producers of the extracellular matrix and regulate its organization. Aberrant signaling in diseases such as fibrosis and cancer can impact the deposition of the matrix protei...

link.springer.com

Great way to find your cancer research community again.

Johanna Joyce@johannajoyce.bsky.social · 2y ago

Inspired by the other amazing starter packs - here's one for cancer researchers! I tried to make this broad - from immunology to genomics to cell biology and so much more.. This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺 Hope its useful! go.bsky.app/FEoaJMc

Congratulations to Clare Isacke for being awarded Women in Science for 2024 by the Metastasis Research Society! Well deserved!