New research from the Hudson Institute links loss of NLRC5 in macrophages to increased AXL/MERTK signaling and a #tumor-permissive environment in #Hpylori-associated gastric #lymphoma. AXL and MERTK are druggable - findings may open new treatment options. lnkd.in/p/e6tXXs5b
Dr. Melvin Sanicas
@vaccinologist.bsky.social
Physician-scientist MD MSc MBA #FIDSA #FRSPH #FRSA #FAcadMEd #TOYM Science & Medicine '21 #PAFIOO #PresidentialAward '24 #Scicomm #Immunology #GlobalHealth
University of Minnesota @uminnpress.bsky.social @umn-idim.bsky.social researchers identified a highly potent experimental #Ebola entry inhibitor. Still early stages but this is promising! www.linkedin.com/posts/drmelv...
A @uniofsurrey.bsky.social study published in Nature Communications found that the Clade IIb B.1 strain behind the 2022 #mpox #outbreak was less virulent than its ancestor despite only 46 nucleotide differences. #virology #mpxv www.linkedin.com/posts/drmelv...
What will the future of #healthcare #lifesciences look like and where could you fit into it? From digital innovation to #GlobalHealth, careers in #health and life sciences are evolving fast. #StudyUK @britishcouncil.bsky.social #UKAlumni Register here: joinalumniuk.britishcouncil.org/event-regist...
Inside the #SagradaFamília, light becomes part of the architecture. #Gaudi’s tree-like columns and stained glass create a luminous forest of gold, red, green and blue - where #architecture, #nature, #art and #spirituality seem to merge. La Sagrada Familia is ABSOLUTELY mesmerizing 🇪🇸 ✨
More than 90% of people carry varicella-zoster #virus #VZV, yet its impact may extend well beyond #chickenpox or #shingles. Reactivation can affect nerves, blood vessels and organs (sometimes without a rash) and has been associated with #stroke, cardiovascular events & #dementia. lnkd.in/p/e3PqnA8S
U.S. experts @aafp.org @ameracadpeds.bsky.social @acog.org @idsainfo.bsky.social issued updated 2026–27 respiratory vaccine guidance. #Flu recommended for everyone 6+ months, #COVID19 recommendations vary by age/risk, #RSV prevention targets older adults, pregnancy, infants. lnkd.in/p/e5FsNVds
DRC’s #Ebola #outbreak has surpassed 6,100 confirmed cases and 3,000 deaths. @WHO calls it the fastest-moving Ebola #epidemic ever recorded. Many cases remain outside known transmission chains; no licensed vaccine proven against #Bundibugyo #virus. www.linkedin.com/posts/drmelv...
Sleeping ~78 minutes less each night for 6 weeks was linked to +0.45 kg #bodyweight, a larger waist and more sedentary time. The takeaway? Weight management may not just be about #food and #exercise. #Sleep matters too! www.linkedin.com/posts/drmelv...
New lab data from @goetheuni.bsky.social Frankfurt + Universitätsmedizin Frankfurt suggest seminal fluid may enhance #infection by helping the #mpox #virus #MPXV attach to human cells more efficiently. Semen is NOT required for transmission but may amplify infection www.linkedin.com/posts/drmelv...
Sierra Leone’s 2025 #mpox #outbreak is a warning against oversimplifying risk. Mortality was 14× higher with severe immunosuppression, 20× higher with uncontrolled HIV, yet nearly two-thirds of deaths occurred in people without #HIV. www.linkedin.com/posts/drmelv...
Two #Frankfurt Airport employees died after contracting #malaria in a cluster of cases believed to have been caused by infected #mosquitoes brought into the country on an aircraft. This is rare but global travel can move disease vectors as well as people. #OneHealth #GlobalHealth lnkd.in/p/e6NwfhMR
The US FDA has approved Revolution Medicines #Rasonque #daraxonrasib, a first-in-class RAS-targeted therapy for previously treated metastatic #pancreaticcancer. In a 500-patient trial, median overall survival was 13.2 months vs 6.7 months with standard #chemotherapy lnkd.in/p/eVvTBZJ3
A locally acquired fatal #WestNilevirus case has been reported in the Netherlands, with 3 probable domestically acquired #infections reported so far in 2026. Individual risk remains low but this is a reminder that #mosquito-borne disease patterns in Europe are shifting. #OneHealth lnkd.in/p/ecS_TGQD
New data: #Shingrix #vaccination may be associated with a LOWER RISK of #heartattack, #stroke and other cardiovascular events in older adults. This is observational, so it does not yet prove causality but promising for #healthyaging. www.linkedin.com/posts/drmelv...
Pennsylvania has reported its first #measles-related deaths in 35 years, amid the highest U.S. measles case count since 1991. Both individuals were unvaccinated. A reminder: measles is NOT benign, and declining #vaccination coverage has REAL consequences. www.linkedin.com/posts/drmelv...
New CDC data suggest #mpox may be transitioning toward #endemic circulation in the U.S. Persistent #MPXV transmission continues; unvaccinated patients had 9.73x higher odds of hospitalization vs. fully vaccinated patients. Surveillance + #vaccination remain critical. www.linkedin.com/posts/drmelv...
NEW #Cochrane evidence and gap map finds that #dengue prevention has plenty of #research but NOT enough high-quality synthesis for policymakers. Key gaps: vector control, implementation, behavioral outcomes, real-world vaccine delivery, more. www.linkedin.com/posts/drmelv...
A new Science Advances study from @ucberkeleyofficial.bsky.social explores a different #obesity strategy: not just helping people eat less but helping the body burn more energy. In mice, #TOFA increased energy expenditure, reduced #fat, preserved lean mass + improved glucose. lnkd.in/p/e6KASpuH
The most dangerous animal is not the shark, lion, snake or even humans. It is the #mosquito. #Mosquitoes transmit some of the world’s most consequential infectious diseases including #malaria #dengue #yellowfever #chikungunya #Zika and #WestNileVirus. Video by Kurzgesagt. #WorldMosquitoDay
🆕 #Moderna and #Merck report positive Phase 3 results for personalized #mRNA therapy intismeran autogene + #pembrolizumab in resected Stage IIB–IV #melanoma. A major proof-of-concept for individualized #cancervaccines and mRNA #immunotherapy. www.linkedin.com/posts/drmelv...
Grateful to The #GlobalFilipino Magazine #TGFM for sharing my story from Bacolod to a career in #globalhealth, infectious diseases and #outbreaks to this meaningful recognition in Switzerland. #JoseRizalHeritageAward #GlobalPinoy #PinoyAko theglobalfilipinomagazine.com/filipino-sci...
Strong #realworldevidence #RWE data from #Australia: maternal #RSV #vaccination was 80.8% effective against RSV-related hospitalization through 6 months of age. #VaccinesWork #VaccinesSaveLives www.linkedin.com/posts/drmelv...
A Swinburne University study found that #sulforaphane, a compound found in #broccoli, may increase frataxin levels & protect vulnerable nerve cells in #FriedreichAtaxia. The compound also appears to reduce cellular stress + #inflammation - 2 key disease processes journals.sagepub.com/doi/10.1177/...
A 2024 @bmj.com #PublicHealth paper on #COVID19 was #RETRACTED because it counted excess deaths but did NOT establish their causes. Real data can support misleading conclusions when #correlation is treated as causation. www.linkedin.com/posts/drmelv...
NEW @ohsunews.bsky.social study: a combination of ART, broadly neutralizing antibodies + CCR5-blocking #leronlimab, started within ~3 days of #HIV #infection prevented viral rebound in newborn nonhuman primates. Intervene early. Promising. Looking forward to human #clinicaltrials. lnkd.in/p/eB3YA8YV
Grateful to the @lshtm.bsky.social for recognizing my election as a Fellow of the @idsainfo.bsky.social Infectious Diseases Society of America #FIDSA. I completed my MSc in Infectious Diseases at the #LSHTM so this recognition is especially meaningful. mailchi.mp/1e21214192b4...
NEW @mayoclinic.org @mayocliniccancer.bsky.social researchers identified TRAILshort as a potential immune “off switch” that suppresses #Tcell signaling. Blocking #TRAILshort restored immune activity, a possible target for #cancer #immunotherapy. www.linkedin.com/posts/drmelv...
A new @bostonchildrens.bsky.social study published in @nature.com found that severe #COVID19 can reactivate dormant #viruses. #Anelloviridae reactivation was associated with #longCOVID; #inflammation, not only immune suppression, may be an important trigger. www.linkedin.com/posts/drmelv...
#Mpox in 2026 does not look exactly like it did in 2022 and that is why clinicians must stay alert. Risk remains low for most people, but the #virus is still circulating, its geographic footprint is changing, vulnerable patients face serious consequences. www.linkedin.com/posts/drmelv...