Happy to share our new paper @vaquerolab.bsky.social in Science Advanced on SIRT2 and MOF antagonism in mitosis. Thanks to all the authors and collaborators ! Together with our recent Nature and Nature Comm, this closes an fantastic period for the lab. www.science.org/doi/10.1126/...
SIRT2 antagonizes MOF function during mitotic entry
The interplay between SIRT2 and MOF regulates G2-M transition.
science.org
Happy to share our new study published in @nature.com Great work by Nicolas Simonet, a joint effort between the Lee and @vaquerolab.bsky.social @carrerasijc.bsky.social labs, uncovering a role for SIRT7 in X dosage compensation. Many thanks to all collaborators and funders. rdcu.be/fnBBz
SIRT7 regulates dosage compensation and safeguards the female X chromosome
Nature - SIRT7 safeguards X-chromosome integrity and dosage balance with autosomes.
rdcu.be
Thrilled to share that our proposal has been awarded a @CaixaResearch.bsky.social project! 🎉 A collaborative effort between @vaquerolab.bsky.social, Menendez Lab, Ribera lab @CarrerasIJC.bsky.social and Dominguez lab at idis_research to develop an innovative B-ALL strategy Grateful for the support!
1/ 🅱️-cell acute lymphoblastic leukemia is the ➕ frequent childhood cancer and many patients relapse after treatment. With a #HealthResearch grant, @vaquerolab.bsky.social is investigating how restoring the function of the PAX5 protein could help to slow the disease.👇 https://tinyurl.com/4978mbnp
2/ 🤝 The project, carried out at @carrerasijc.bsky.social, is conducted in consortium with Eduardo Domínguez, from the Foundation Institute of Health Research in Santiago de Compostela.
1/ Today we'd like to congratulate the projects selected in the 2025 #HealthResearch #laCaixaFoundation Call!👏 Throughout the morning, we'll be presenting 3⃣4⃣ pioneering research projects that seek to transform the future of health. Find out all about them in our blog.👇 https://tinyurl.com/srzm8bxe
🚨 We are hiring! A #Postdoc position is open in the Chromatin Biology Lab to work on Sirtuins & Leukemia 🧬 If you are up to the challenge join our @vaquerolab.bsky.social team at @CarrerasIJC.bsky.social Apply here 👉 careers.carrerasresearch.org/jobs/6549033-v… Sirtuins rule! 🦾
VAC_82_2025 - POSTDOCTORAL RESEARCHER (Chromatin biology laboratory) - Institut de Recerca contra la Leucèmia Josep Carreras
Join the Josep Carreras Leukaemia Research Institute and contribute to our mission of innovating and advancing the fight against leukaemia and other hematologic diseases.
careers.carrerasresearch.org
Happy to participate in the last article of the Cuartero lab @NatureComms on CEPBA and AML. Fantastic work of Maria Cadefau, and the rest of contributors. t.co/DfSHISBJTz
https://www.nature.com/articles/s41467-025-58712-7
t.co
With great sadness, we announce the passing of Dr. Joan Guinovart, founder, former scientist, director, and Emeritus Professor of IRB Barcelona. Our deepest condolences to his loved ones and the IRB Barcelona community. You will always be remembered, Captain.
Happy to announce that our work @vaquerolab.bsky.social on the SIRT7/PAX5 interplay in B-cell development has been published in the Dec issue of Nature Immunology. Huge thanks to collaborators and funding agencies for their contribution. Sirtuins rule!! 🦾 www.nature.com/articles/s41...
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5 - Nature Immunology
Gámez-García et al. show that the deacetylase SIRT7 modulates the acetylation of Pax5 and its ability to repress alternate lineage programs and promote B cell differentiation and commitment in B cell ...
nature.com
Another PhD in the @CarrerasIJC neighborhood! Fantastic experience yesterday in the PhD defense of Andrés Gámez, a highly talented student from our group, on the role of SIRT7 in B-cell differentiation through PAX5. Many thanks to the PhD committee. Sirtuins rule! 🦾🦾🦾
