Congratulations to our Hancock, Streblow, and Caposio lab teams and their contributors! Their paper explores the UL22A protein and the UL22A Y65 and Y69 residues, and how they're necessary for efficient HCMV reactivation from latency in CD34+ hematopoietic progenitor cells. And that UL22A...

Please join us in congratulating our Bimber, Hansen, Labriola, Axthelm, and Picker labs and affiliate lab teams with their contributors, on their publication in Frontiers Immunology! Their paper uses T Cell Antigenic Recognition Sequencing (TAR-seq) to provide a precise and comprehensive...

Congratulations to our Estes and Okoye lab teams, with their contributors, on their recent paper! Their review analyzes the emerging evidence on HIV associated neuropathology in antiretroviral therapy suppression in people with HIV, focusing on the role of the gut-brain axis.

A team at @ohsunews.bsky.social this month became the first in Oregon to implant a new type of radioactive tile roughly the size of a postage stamp to improve the outcome for patients with #BrainTumors.

OHSU is first in Oregon to implant device in brain to treat tumor

Targeted radiation therapy aims to improve survival, prevent tumor recurrence.

news.ohsu.edu

O'nyong-nyong virus (ONNV) is a mosquito-borne alphavirus first isolated in 1959. Currently, we have a limited understanding of ONNV infection and disease in relevant animal models, which restricts the evaluation of vaccines and therapeutics. Our Streblow, Axthelm, and Labriola lab and affiliate...

Congratulations to VGTI Associate Professor Rebecca Skalsky, Ph.D., @rskalsky.bsky.social for her new paper! Her review looks at common themes for both human and viral miRNAs in viral infection processes, which highlights their dual functions in suppressing and promoting viral life cycles.

We are happy to celebrate our Wilder Lab Team on their feature article in OHSU News! They are hard at work researching a universal vaccine against malaria. Great job everyone. Read more by visiting: news.ohsu.edu/2026/07/01/s...

Study reveals path for universal vaccine against malaria

A T cell-based vaccine that targets the parasite as it infects the liver opens new possibilities for malaria, other parasite vaccines.

news.ohsu.edu

Celebrating our newest faculty member Emily Voigt, Ph.D., on recieving the OCTRI Biodmedical Innovation Drug Award! Congratulations Emily 🎉 Her work will focus on an NLC-Delivered saRNA vaccine for Respiratory Syncytial Virus.

Congratulations to our Wilder lab team for securing a new grant award! Their work will focus on developing a heterologous vesicular stomatitis virus prime-virus vesicle boost vaccine regimen for Malaria, that can generate a protective cellular and humoral immunity to multiple...

Please join us in celebrating Caralyn Labriola, BVMS DACVP, and team, on receiving a grant from the Collins Medical Trust! Her study will examine translational characteristics of the nasopharyngeal lymphatic plexus across humans and non human primates at the anatomic, cellular and molecular level.

Congratulations to our Wilder lab team, and contributors, on their recent publication! Currently, both licensed Malaria vaccines target only the circumsporozoite protein expressed during early stages of Plasmodium falciparum infection. These results provide the proof-of-concept evidence that...

Amazing news to share today— OHSU VGTI Professor Scott Hansen, Ph.D, receives a promotion to Quality and Operations Lead for the University Shared Resources (USR)! 🎉🥳 Congratulations Scott!

Congratulating Professor Scott Hansen, Ph.D., who has been awarded a $210,000 grant from the National Institute of Allergy and Infectious Diseases! This is part of the larger award from National Institutes of Health on March 6, 2026, to support research evaluating a prototype tuberculosis vaccine.

Amazing contribution from our very own Brandon Wilder, Ph.D., on a new publication which characterized and optimized an Aotus nancymaae non-human primate (NHP) model of Plasmodium vivax (Pv) blood stage infection to enable the testing of novel vaccines and immunoprophylactics.

Congratulations to our Streblow and DeFilippis lab teams, with their contributors, for their recent publication! Their work both represents a thorough in vivo immune characterization of the effects of transmembrane STING agonism and demonstrates the efficacy of a potential vaccine adjuvant and...

Celebrating Louis Picker, M.D, and his publication in Nature Microbiology! His team, along with researchers from Frederick National Laboratory for Cancer Research and Harvard Medical School, used NHP's to track where HIV comes from when it returns after treatments stop.

Congratulations to our Frueh, Picker, Burwitz, Hansen, and Sacha lab teams for securing a new patent! Their patent relates to methods that generate an immune response for the treatment or prevention of hepatitis B virus infections.

What would a world free of HIV look like? Tune into the OHSU Foundation for their special feature with VGTI affiliate professor, Jonah Sacha, PhD. Explain It! is a video series that spotlights the impactful research taking place at OHSU. Learn more by visiting: ohsufoundation.org/stories/expl...

Congratulations to our Streblow lab for securing a grant award with Pacific National Northwest Laboratory, which focuses on identification of broad spectrum anti-infectives.

We are pleased to announce that our Hansen Lab has been awarded a grant with Tufts University, focusing on the spatial multimoic stop redict granuloma trajectory and bacterial restriction during vaccination. Congratulations!

Congratulations to our Streblow Lab and their contributors! They used multiple methods to investigate joint-associated tissues in alphavirus-infected mice at a late stage of infection. Their data suggests that macrophages harbour replicating viral RNA and contribute to the sustained joint...

Reposting with correction: a recent publication from our Caposio, Malouli*, and Hancock lab teams with their contributors; where they establish Notch pathway suppression as a critical viral strategy for reactivation and highlight potential therapeutic targets for preventing HCMV disease.

Congratulations to our Okoye and Picker labs, and their contributors! This week they published a paper exploring the trajectories of multiple individual SIV barcode lineages across in vitro infection of cell lines and primary cells and after mucosal and intravenous infection of macaques.

In this new publication our Haigwood affiliate lab with their contributors and invited experts, discuss the current state of science to identify challenges hindering advancements, and propose recommendations for overcoming these challenges. Read more at: pubmed.ncbi.nlm.nih.gov/41837632/

Amazing work by our Okoye, Hansen, Estes, Axthelm, Picker lab teams with their contributors, on their new publication investigating treatments using barcoded SIVmac239 in rhesus macaques! Read more about SIV by visiting: pubmed.ncbi.nlm.nih.gov/41617893/

Congratulations to our Okoye, Estes, Axthelm, and Picker Lab teams with their contributors on their new publication which investigates the magnitude and activation of SIV-specific CD8+ T cells. Read more about SIV T Cell responses by visiting the below link. pubmed.ncbi.nlm.nih.gov/41609736/

In this recently updated publication our Frueh, Streblow, and Hansen lab teams with their contributors, explore Human cytomegalovirus (HCMV) encoding and four viral Fc-gamma receptors (vFcγRs) that counteract antibody-mediated activation in vitro. Read more at: pubmed.ncbi.nlm.nih.gov/39885150/

In their new publication, our Sacha affiliate lab with their contributors, explore the association with ccf-mtDNA dynamics in acute and chronic HIV infections. Read more at: pubmed.ncbi.nlm.nih.gov/41556528/

In this review, our Hessell and Haigwood affiliate lab team with their contributors, address human monoclonal antibodies (mAbs) as a strategy for treating and preventing viral infections in pediatric populations. Read the full article at: pubmed.ncbi.nlm.nih.gov/40174915/

Our Bimber affiliate lab team with their contributors, recently published a paper where they seek to understand the degree and implications of intraspecies structural variation is essential to all biomedical research using rhesus macaques as a model.