Our new paper by postdoc Man Wu "The centrosomal hub unifies regulatory factors of NLRP3 inflammasome activation" provides a simple, unified insight on this complicated beast of NLRP3 inflammasome! pnas.org/doi/10.1073/...
Prof. Hao Wu
@wulabharvard.bsky.social
Asa and Patricia Springer Professor of Structural Immunology @Harvard Medical School and Boston Children's Hospital. #immunology, #structural biology, #world peace
How does the NLRP3 inflammasome form dense condensates at the microtubule organizing center to drive pyroptosis? Hao Wu, Harvard University, discusses here: faculti.net/visualizing-...
Excited to share our paper on the NLRP3 inflammasome condensate at the Microtubule Organizing Center (MTOC) by "precise!" cryo-electron tomography (cryo-ET), in collaboration with Jue (phyllis) Wang in the labs of Grant Jensen (BYU) and Pete Dahlberg (Stanford)! www.science.org/doi/10.1126/...
I’m so excited and proud that my student Jennifer Wang has received so many kudos for her Master’s thesis talk in Immunology @harvardmed.bsky.social Congratulations, Jennifer!
I am excited to share with you an amazing video on the NLRP3 inflammasome pathway generated by talented Ann Liu from the Janet Iwasa lab @jiwasa.bsky.social @ann-hl.bsky.social. It shows the real structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. Enjoy!