Our first fellowship interview day of the season started off right, with 2nd year fellow Dr. Paola Gudiño giving Renal Rounds on HIV and the kidney. Tat & gp160, TGFβ-driven matrix remodeling, mesangial apoptosis, and Sidekick-1 in the glomerulus! @ubrewster.bsky.social @yaleschoolofmed.bsky.social

Our study of acute interstitial nephritis is out in Nature Communications. We used imaging mass cytometry and single-cell spatial transcriptomics on 106 human kidney biopsies to ask what separates AIN from other causes of AKI at the tissue level. 🧵 www.nature.com/articles/s41...

1/ Excellent Renal Rounds this morning: 2nd year fellow Dr. Akshaya Ramaswami on "Malignant Hypertension and Thrombotic Microangiopathy: Can they complement each other?" A patient presents with severe HTN, AKI, and TMA. Which one caused the other? The answer changes the treatment. 🧵

Drs. Alani and Asch at Renal Rounds: “To Include or Not Include the Kidney: Decision-Making in Simultaneous Organ Transplantation.” SLKT volumes keep climbing, but deciding who actually needs the kidney is still a challenge. Excellent discussion from the room!

How do B cells survive the hypertonic kidney in lupus nephritis? At Medical Grand Rounds, Dr. Irene Chernova took us from the γ subunit of the Na-K-ATPase to extracellular ATP signaling via P2RX4 and P2RX7. Genuinely surprising axis & terrific discussion. Excited for what's next!

Renal Rounds this morning: 2nd year fellow Dr. Erica Marnet on “Lupus Nephritis: Treatment Paradigm.” Dysregulated B cells, sustained interferon signaling & how the mechanisms map onto what we actually reach for in clinic.

Home dialysis is flexible, effective, and cheaper. So why is it still underused, especially among low-income patients? Lauren Killingsworth and Ladan Golestaneh find the answer in 60 years of dialysis politics. New in @annalsofim.bsky.social: www.acpjournals.org/doi/10.7326/...

Dialysis and the Politics of Self-care: The Enduring Effects of Barriers Imposed on Home Dialysis | Annals of Internal Medicine

Home dialysis can offer persons with kidney failure a more individualized, flexible, and independent method of dialysis compared with in-center hemodialysis (ICHD), with similar survival outcomes. Hom...

acpjournals.org

Yale Nephrology faculty gathered at Harvest Wine Bar in downtown New Haven to celebrate Dr. Marzuq Billah and Dr. Deepa Jayaram and wish them well in their next chapters! Grateful for all they've brought to our section. Best of luck in what comes next!

Summer physiology noon conferences are back, starting today with Dr. Peter Aronson! A rite of passage for generations of Yale Nephrology fellows, learning physiology from the scientists who helped discover it. And somehow there is always something new to learn! @yaleschoolofmed.bsky.social

First Fellows Tuesday Teaching Conference for our first years, led by Dr. Perazella giving his high yield and practical annual Poisonings and Intoxications lecture! @ubrewster.bsky.social @yalemed.bsky.social

Stacks of nephrology textbooks, the small blue book all our alumni still have, & Dr. Brewster's meticulous binder: it's Orientation Day for our 2026 Nephrology Fellows! Welcome to Yale, Drs. Angammana, Min, Nazir, Okoro, Ramadhar, Wortman, & Yee! @ubrewster.bsky.social

Few nights mean as much to us as our fellowship graduation. Last night the Yale Nephrology fellowship gathered at the Yale Schwarzman Center to celebrate our graduating fellows and the faculty who trained them. 🎓

This core curriculum by Laura Aponte Becerra & Sherry G. Mansour reviews the physiology of exercise on kidney function and provides evidence-based strategies for patient counseling and risk reduction: bit.ly/3YK6uXv (OPEN ACCESS) @yalenephrology.bsky.social

Last Renal Physiology session of the year, done right: cake from Dr. Krishnan, pizza, and Nephrology Jeopardy hosted by second year fellow Dr. Calvin Henderson! Blue and Red teams currently neck and neck at 500... @ubrewster.bsky.social

Renal Rounds this morning: our 2nd-year fellows presented their QI project on pre-biopsy DDAVP. A genuine multi-cycle PDSA effort, mapping where doses got delayed or missed and building the fix into a new kidney biopsy order set. Awesome job! 👏 @ubrewster.bsky.social @yalemed.bsky.social

Always a highlight: Dr. Crowley’s fellows Tuesday teaching session on the role of the dialysis medical director, covering patient safety responsibilities and the CMS Conditions for Coverage that define the job. Engaging and practical as always!

First-year fellow Dr. Akshaya Ramaswami took on green nephrology at renal rounds today, walking through water conservation strategies in hemodialysis and the many ideas on the horizon for shrinking our environmental footprint! 👣🌱

Happy Nurses Week to our West Haven VA dialysis team! 1st year fellow Dr. Paola Gudino jumped in for Superhero Day and 70s Day this week. So grateful for the nurses who care for our patients with skill, heart, and (this week) excellent fashion choices. @yalemed.bsky.social @ubrewster.bsky.social

First multicenter US real-world data on terlipressin for HRS-AKI from the HRS-HARMONY consortium. Response rates and adverse events tracked the CONFIRM trial closely. Yale among 16 contributing sites, with Dr. Justin Belcher! 🔗 ⬇️ pubmed.ncbi.nlm.nih.gov/42107856/

U.S. Experience with Terlipressin in Hepatorenal Syndrome: Response, Mortality, and Transplant Outcomes - Results from the HRS Harmony Consortium - PubMed

This U.S. multicenter study provides insights into real-world use of terlipressin for HRS-AKI. Terlipressin was frequently used in patients with ACLF grade 3. Adherence to FDA labeling criteria was as...

pubmed.ncbi.nlm.nih.gov

Renal Rounds this morning: transplant fellow Dr. Khaing Wei on “Precision Diagnostics in Renal Transplantation Part II,” walking us through how the Molecular Microscope Diagnostic System (MMDx) classifies renal allograft injury at the molecular level.

Photo day at Yale Nephrology. 30+ people, one staircase, and a group of fellows with serious range. 2026 section photos are in! @yalemedicine.bsky.social @yalemed.bsky.social @ubrewster.bsky.social @meganbaker.bsky.social @fperrywilson.bsky.social

New editorial from Drs. Aklilu & Shirali in @asnpublications.bsky.social - “Mind the Gap: eGFR Discordancy and Melphalan Dosing in Multiple Myeloma.” For cancer patients, choosing Cr vs cystatin C eGFR isn’t academic - it changes chemotherapy dose and toxicity. 🔗 journals.lww.com/kidney360/fu...

A real pleasure to host Dr. Thomas Kleyman for the Robert W. Berliner Lecture! We got back-to-back fundamental talks: epithelial Na+ channel regulation on Thursday and new perspectives on renal potassium handling on Friday. Thanks for two great days of physiology! @upmc.com @yalemed.bsky.social

Renal Rounds this morning with Dr. Daniel Guevara-Pineda and colleagues from Clínica Anglo Americana in Lima, Perú on the current status and challenges of kidney transplant in Perú. Excited to be developing this new sister transplant partnership with Yale and see where it leads!

One of our fellows' favorite outpatient rotations? PD clinic. Today alongside Dr. Brewster (@ubrewster.bsky.social), Drs. Moss, Alani, and Henderson worked on manual exchanges and troubleshooting catheter and exchange hiccups -- hands-on learning at its best!

1/ Renal Rounds this morning: first-year fellow Dr. Laura Onuchic walked us through Alport syndrome, from GBM biology to the new genomics-based classification, gene therapy horizons, and post-transplant considerations! 🧵on the highlights:

Congrats to Fatemeh Asghari, Morven Graham & Will Chang! Their NephroFlux Device uses microfluidics to study how fluid shear stress shapes kidney tubular cells - opening doors for disease modeling and nephrotoxicity testing. @asaiojournal.bsky.social journals.lww.com/asaiojournal...

This morning at Renal Rounds, first year fellow Dr. Erica Marnet delivered a masterclass on C3 glomerulopathy - a rare but mechanistically rich complement-mediated kidney disease. Key pearls:🧵

2nd year fellow Dr. Becky Kurian just returned from a rotation at Mulago National Referral Hospital in Uganda through the Makerere University–Yale collaboration. Grateful for this partnership and the remarkable colleagues who make experiences like hers possible. Looks like so much fun!

Excellent Renal Rounds this morning by first-year fellow Dr. Fernando Onuchic on Mesoamerican Nephropathy - a real conversation starter! 👏 Key takeaways from his presentation on this important and underrecognized topic 🧵 @ubrewster.bsky.social