Yosef (Yossi) Buganim
@yossibuganim.bsky.social
Scientist, interested in epigenetic reprogramming, cellular rejuvenation, and embryogenesis. Head of a stem cell lab at the Hebrew University of Jerusalem and co-founder and CSO at Ananda Labs https://www.buganimlab.com/ https://www.ananda-labs.bio
www.nature.com/articles/s41... (1/n) Ever wonder how transcription factors locate, "invade," and activate their enhancers during cell fate acquisition? 🧬🚀 Check out our latest collaborative work with the Soufi lab, now published in @Nature
Nucleosome fibre topology guides transcription factor binding to enhancers - Nature
Motif grammar on nucleosome fibres acts as signpost elements, directing TF combinatorial binding to enhancers.
nature.com
www.pnas.org/doi/10.1073/... Happy to share our recent collaborative study with the Cedar and Stanger labs, identifying the barrier responsible for incomplete epigenetic reprogramming in both in vitro and in vivo transdifferentiation models.
Ananda Labs, founded by @HebrewU 's Prof. Yossi Buganim, was featured in @ISRAEL21c for its groundbreaking research on reversing aging. Their epigenetic reprogramming tech targets age-related diseases, rejuvenates skin, and boosts immune health. www.israel21c.org/the-company-...
Ananda Labs: Slowing down the aging process
Ananda Labs is developing novel solutions for aging-related conditions from wrinkles, to scars to a more youthful immune system through epigenetic editing.
israel21c.org