A hypothalamic-brainstem activity sequence underlies arousal fluctuations during daytime drowsiness https://www.biorxiv.org/content/10.64898/2026.05.26.728061v1

Attentional failures during wakefulness after sleep deprivation are tightly orchestrated in a series of brain–body changes, including neuronal shifts, pupil constriction and cerebrospinal fluid (CSF) flow pulsations @lauradata.bsky.social @ziy027.bsky.social www.nature.com/articles/s41...

Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics - Nature Neuroscience

Yang et al. show that moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered bra...

nature.com

New research shows attention lapses due to sleep deprivation coincide with a flushing of fluid from the brain — a process that normally occurs during sleep. news.mit.edu/2025/your-br...

This is your brain without sleep

An MIT study reveals what happens in the brain as lapses of attention occur following sleep deprivation. During these lapses, a wave of cerebrospinal fluid flows out of the brain — a process that typi...

news.mit.edu

What really happens in your brain when you don’t sleep enough? Our new study in Nature Neuroscience reveals that when you’re sleep-deprived and attention drops, your brain starts to look like asleep: with large waves of CSF rushing through the brain, similar to what happens during sleep.

🎉Excited to share our latest work with @stephaniedwill.bsky.social @ewa-beldzik.bsky.social @lauradata.bsky.social + others 🥱Why does sleep deprivation have negative effects on behavior? We demonstrate that attentional failures caused by SD are coupled to large-scale brain fluid transport.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2y ago

Attentional failures after sleep deprivation represent moments of cerebrospinal fluid flow https://www.biorxiv.org/content/10.1101/2024.11.15.623271v1