Dr. Andrea Sant, DFAAI ’25, University of Rochester School of Medicine and Dentistry, found that protective immunity is more rapid in response to influenza B viruses than influenza A. This could help improve vaccines and therapeutic agents for influenza B. Learn more: https://ow.ly/YvzK50ZweQ8.

Dr. Michelle Cheung, #UofT, used residual patient samples from the IMPACT study to focus on patients with IBD and understand how their T cell responses may differ from those of healthy individuals, finding no difference. Read more in AAI News & Views: https://ow.ly/gkoC50ZvSt4

AAI condemns continued efforts to target Anthony S. Fauci, MD, and warns that attacks on scientists undermine public trust, discourage future researchers, and weaken evidence-based decision-making. 🔗 https://ow.ly/xfK650ZvPmr

AAI Condemns Continued Efforts to Politicize Science and Discredit Scientists - AAI News

The American Association of Immunologists (AAI) is appalled by the continuing efforts to target Anthony S. Fauci, MD, AAI member and one of the nation’s most accomplished physician-scientists and a longstanding member of the immunology community. For more than five decades, Dr. Fauci dedicated his career to advancing biomedical research and protecting public health. His...

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Catarina Hioe (Icahn School of Medicine at Mount Sinai) closed out the Advanced Course in Immunology with a lecture on “Vaccines,” covering lessons from COVID-19 mRNA vaccines, how both immune and non-immune factors shape vaccine responses, and the elusive goal of HIV vaccines.

The new AAI Learning Center gives you access to #IMMUNOLOGY2026™ with 450+ on-demand sessions now available to attendees. Members save big, so renew today with summer pricing! Explore the Highlights, featuring select invited program sessions, CME courses, webinars, and more: learning.aai.org.

In her “Lessons from Inborn Errors of Immunity” lecture, Megan Cooper (WashU Medicine) explored the diversity of inborn errors of immunity, discoveries made through patient investigation, & what the future holds for uncovering their underlying mechanisms and developing treatments.

Joanne L. Viney (Seismic Therapeutic) opened the final day of the Advanced Course with her lecture, “Drug Discovery and Development: Immunotherapeutics for Autoimmune Disease,” sharing insights into the challenging yet rewarding path of developing new therapies. #AAIcourses

#ICYMI Following her lecture on the “Effect of the Microbiome on Immunity,” Cathryn Nagler (University of Chicago) answers questions about how the gut-associated lymphoid tissue (GALT) distinguishes friend from foe—tolerating beneficial microbes while mounting immune responses against pathogens.

A #leakygut might increase the severity of food allergies caused by changes in the gut #microbiome that increase leaky gut, according to new research from the Center for Immunology-UMN and published in The Journal of Immunology: https://ow.ly/HhQg50ZuGFl.

In his “Engineering T Cell Immunity” lecture, Nathan Singh (Washington University School of Medicine) discussed how advances in protein engineering, gene therapy, and antigen selection are transforming cancer treatment. #AAIcourses

Gavin Dunn’s (Harvard Medical School) “Tumor Immunology” lecture discussed how cancer immunology evolved from immunosurveillance to immunoediting, explaining how tumors evade immunity. #AAIcourses

In his “Neuroimmunology” lecture, Jonathan Kipnis (WashU Medicine) questioned what makes the CNS “immune privileged” if its antigens reach T cells via lymphatics and meningeal APCs—reshaping how we think about brain-immune interactions.

In her “Immunometabolism” lecture, Erika L. Pearce (Johns Hopkins University SOM) opened Day 5 of the Advanced Course in Immunology by highlighting cutting-edge research revealing how immune cell function is tightly linked to — and can even reshape — whole-body metabolism.

Dr. Andrea Sant, DFAAI ’25, University of Rochester Medicine, found that protective immunity is more rapid in response to influenza B viruses than influenza A. These findings could help improve vaccines and therapeutic agents for influenza B. Read more in AAI News & Views: https://ow.ly/Lbyu50ZuHam.

#ICYMI yesterday, Kristi Kuhn (Univ. of Colorado SOM) answered questions about how T cell tolerance prevents autoimmunity through central & peripheral checkpoints, & how autoimmune disease arises when layered tolerance mechanisms fail, while cancer immunotherapy works by disrupting them. #AAIcourses

Stephen Jameson (University of Minnesota Medical School) gave a comprehensive lecture on “T Cell Memory,” highlighting how memory T cells differ from naïve T cells, the diverse subsets of memory T cells, and the mechanisms behind the generation and long-term maintenance of memory T cells.

Upgrade your immunology expertise at your own pace! Explore the AAI Learning Center for access to comprehensive courses, past lecture libraries, and professional development resources. 🔬 Start learning today: learning.aai.org

Julie Zikherman (UCSF School of Medicine) gave a lecture on “B Cell Tolerance & Autoimmunity,” exploring the mechanisms that maintain B cell tolerance—and how failures in these processes can lead to autoimmunity. #AAIcourses

Deepta Bhattacharya (University of Arizona) opened Day 4 of the Advanced Course in Immunology with a lecture on “B Cell Memory,” covering initial B cell activation, interactions with T cells, the formation of memory B cells and long-lived plasma cells, and recall responses. #AAIcourses

#ICYMI Lawrence P. Kane (University of Pittsburgh Department of Medicine) closed Day 3 yesterday with a deep dive into “Antigen Receptor Signaling,” exploring how T cells discriminate between ligands, models of TCR signal initiation, and the spatial regulation of TCR signaling. #AAIcourses

In his lecture on “T Cell Development,” AAI President Avery August (Cornell University) explained how thymic epithelial cells guide T cell maturation—covering MHC restriction, positive and negative selection, and the emergence of diverse, self-tolerant T cell populations. #AAIcourses

In his lecture on “MHC-restricted Antigen Presentation to T Cells,” Kai W. Wucherpfennig (Dana-Farber Cancer Institute) highlighted antigen presentation as a cornerstone of vaccine efficacy—and a promising therapeutic target in autoimmunity and cancer. #AAIcourses

Stephanie Eisenbarth’s (Northwestern Feinberg School of Medicine) lecture on “Dendritic cells, related cells and initiation of adaptive immunity” highlighted why dendritic cells are the immune system’s most efficient antigen-presenting cells. #AAIcourses 🔗 learning.aai.org

The wait is over–the new AAI Learning Center is LIVE! Revisit #IMMUNOLOGY2026™ with 450+ on-demand sessions now available to attendees. AAI members save big! If you missed us in Boston, you can explore the Highlights, plus, explore CME courses, webinars, and more. 🔗 learning.aai.org

Ali H. Ellebedy (WashU Medicine) opened Day 3 of the Advanced Course with a deep dive into “B Cell Development,” emphasizing the goal: to generate a diverse, functional pool of B cells—each uniquely specific, but free of harmful self-reactivity. #AAIcourses

In his lecture on “The Generation and Modification of Lymphocyte Antigen Receptor Genes,” Eugene Oltz (Ohio State University) described how chromatin accessibility controls where V(D)J recombination occurs during immune cell development.

In his lecture on “Molecular and Cellular Regulation of Inflammation,” Ivan Zanoni (Harvard Medical School / Boston Children’s Hospital) explained how phagocytes detect virulence factor activity to kickstart inflammation. #AAIcourses

In her “Innate Immunity” lecture, Jenny Ting (UNC, Chapel Hill) explored how the body detects infection & tissue damage through pattern-recognition receptors, triggering inflammation, cytokines, interferons, inflammasomes & pyroptosis, with links to autoimmunity and therapies.

Claudia Jakubzick (Dartmouth) gave a lecture on “Myeloid Cells in Immune Responses.” She described how macrophage gene expression & function vary by the tissue in which they reside, & how monocytes influence diverse immune processes such as inflammation and immunotherapy. 🔗 learning.aai.org

Course Director Wayne M. Yokoyama (WashU Medicine) opened Day 2 of the Advanced Course with a lecture on “Innate Lymphoid Cells (ILCs) and NK Cells,” in which he provided an overview of ILCs and NK cells and ended with emerging topics in NK cell biology. #AAIcourses