Light-cycle time-restricted feeding remodels a hidden layer of the cardiac transcriptome through sex-specific transcript switching https://www.biorxiv.org/content/10.64898/2026.09.22.753546v1

The circadian clock regulates KCNH2 (hERG) promoter activity through daily temperature rhythms. https://www.biorxiv.org/content/10.64898/2026.09.28.751769v1

Housing Mice in Thermoneutrality Causes Tissue-specific Changes in Number, Identity, and Phase of Circadian-expressed mRNA Transcripts https://www.biorxiv.org/content/10.64898/2026.05.05.722706v1

A great team effort. @bethaschroder.bsky.social @bpdelisle.bsky.social @universityofky.bsky.social #diabetes #heart #cardiac

brian_delisle@bpdelisle.bsky.social · 9mo ago

🚨🆕🧪🔬 Congrats to @abhiprabhat.bsky.social - dim light at night exacerbates cardiac autonomic neuropathy (CAN) in diabetic mice & CAN disrupts coupling between heart rate and body temp 🫀⏱️ #CardiacAutonomics #Diabetes #Circadian #Physiology #CardioSky www.heartrhythmjournal.com/action/showP...

If you are at #AHA25 go check out Dr. Prabhat’s @abhiprabhat.bsky.social poster- where he identifies feeding behavior as a potential modifiable risk factor for regulating autonomic input to the heart- It is TODAY 11:30am-12:30pm (Central) MC.APB.04 eppro02.ativ.me/web/index.ph... #heart #CardioSky

Thrilled to share our Creative Concepts paper published in Heart Rhythm on how the circadian clock gene Bmal1 mediates sex specific cardiac ion channel expression. authors.elsevier.com/a/1m1jJ5VtUy... @kaesser.bsky.social @bpdelisle.bsky.social @abhiprabhat.bsky.social

I was awarded the best speaker (1st Prize) in Slam competition among other fantastic presenters at the Annual Career & Research Symposium 2025 at UKY. The vice-president of research gave amazing and inspiring talk. Another year of fruitful postdoc journey with people who care about the science.

I really enjoyed Kentucky chapter of American Physiological Society #KPS 2025 meeting. Twice in a row, I was able to secure the 1st prize in Poster competition (2024) and this year in Postdoc Talk Competition (2025). Amazing support from @bpdelisle.bsky.social @bethaschroder.bsky.social

@jmccardiology.bsky.social put an incredible cover image (mine 😂😂) for the March issue. Under the guidance of @bpdelisle.bsky.social and @bethaschroder.bsky.social

brian_delisle@bpdelisle.bsky.social · 2y ago

Congrats @abhiprabhat.bsky.social on generating an amazing cover for the @jmccardiology.bsky.social March issue!

Broken circadian clock: The emerging neuro-immune link connecting depression to cancer This review systemically describes the fundamental mechanisms of #circadian clocks and the interacting relationships among broken circadian clock, #cancer & #depression. 👇 www.sciencedirect.com/science/arti...

Excited to share our latest review out in JMCC examining circadian impacts on sudden cardiac death and cardiac electrophysiology. nam04.safelinks.protection.outlook.com?url=https%3A... @bpdelisle.bsky.social @abhiprabhat.bsky.social @kaesser.bsky.social

Congrats @bpdelisle.bsky.social ! Circadian influences on sudden cardiac death and cardiac electrophysiology

brian_delisle@bpdelisle.bsky.social · 2y ago

🚨🫀⏰ Delisle et al 😉 review circadian mechanisms and sudden cardiac death🧬 Day-night cycles in ion channel regulation and myocardial protection impact arrhythmia risk💓👉 www.jmcc-online.com/article/S002... #IonChannels #Circadian #CardioSky #Arrhythmias #Physiology

Latest Review explores circadian mechanisms and sudden cardiac death. @jmccardiology.bsky.social #circadian #heart #physiology

brian_delisle@bpdelisle.bsky.social · 2y ago

🚨🫀⏰ Delisle et al 😉 review circadian mechanisms and sudden cardiac death🧬 Day-night cycles in ion channel regulation and myocardial protection impact arrhythmia risk💓👉 www.jmcc-online.com/article/S002... #IonChannels #Circadian #CardioSky #Arrhythmias #Physiology

Congrats!!! @abhiprabhat.bsky.social @kaesser.bsky.social @bethaschroder.bsky.social

brian_delisle@bpdelisle.bsky.social · 2y ago

🚨🫀⏰ Delisle et al 😉 review circadian mechanisms and sudden cardiac death🧬 Day-night cycles in ion channel regulation and myocardial protection impact arrhythmia risk💓👉 www.jmcc-online.com/article/S002... #IonChannels #Circadian #CardioSky #Arrhythmias #Physiology

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries www.nature.com/articles/s41...

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries - Nature Medicine

Estimates from the Global Dietary Database indicated that 2.2 million new type 2 diabetes and 1.2 million new cardiovascular disease cases were attributable to sugar-sweetened beverages worldwide in 2...

nature.com

The core circadian clock factor, Bmal1, transduces sex-specific differences in both rhythmic and non-rhythmic gene expression in the mouse heart academic.oup.com/function/adv...

The core circadian clock factor, Bmal1, transduces sex-specific differences in both rhythmic and non-rhythmic gene expression in the mouse heart

Abstract. It has been well established that cardiovascular diseases exhibit significant differences between sexes in both preclinical models and humans. In

academic.oup.com

A very interesting article about the impact of the light/dark cycle on metabolism! www.science.org/doi/10.1126/...

Light modulates glucose and lipid homeostasis via the sympathetic nervous system

Light exerts circadian-independent effects on glucose and lipid metabolism.

science.org

New paper from Spencer Procopio and Xiping Zhang and other colleagues. While looking at sex specificity in mouse heart circadian transcriptome we found that Bmal1 is a key upstream TF in cardiomyocytes for non-circadian sex differences as well academic.oup.com/function/adv...

The core circadian clock factor, Bmal1, transduces sex-specific differences in both rhythmic and non-rhythmic gene expression in the mouse heart

Abstract. It has been well established that cardiovascular diseases exhibit significant differences between sexes in both preclinical models and humans. In

academic.oup.com

🚨 🔬 Zhang et al drops 🤯 study- Female 🐭 hearts 🫀 dance 💃 to a different circadian rhythm than male 🐭 hearts🫀 Cardiomyocyte-specific circadian clock ⏰ Bmal1 is vital in conferring sex-specific gene expression😳👉 academic.oup.com/function/adv... #CardioSky #Physiology #Circadian 👏 @kaesser.bsky.social

I am excited to share a new review led by Spencer Procopio, a PhD student in the lab. Clockwork conditioning: Aligning the skeletal muscle clock with time of exercise focusing on cardiometabolic health. www.sciencedirect.com/science/arti...

Clockwork conditioning: Aligning the skeletal muscle clock with time-of-day exercise for cardiometabolic health

Circadian rhythms have evolved to synchronize gene expression, physiology, and behavior with time-of-day changes in the external environment. In every…

sciencedirect.com

🌙 Ever wondered how artificial light at night affects your #autonomic nerves and #heart? New #circadian research with @bethaschroder.bsky.social reveals some surprising sex-specific effects on cardiovascular health in mice 🐭 #ChronoBiology #HeartHealth #shiftwork www.nature.com/articles/s42...

Dim light at night unmasks sex-specific differences in circadian and autonomic regulation of cardiovascular physiology - Communications Biology

Restricted feeding to the dim light at night restores disrupted day-night autonomic and cardiovascular rhythms but not activity in male and female mice.

nature.com