🎉 Our new GWAS of anxiety symptom severity is out today in Nature Human Behaviour! It's been a pleasure working on this one as part of the core analyst team, and making the infographics for the @pgcgenetics.bsky.social thread below 👇

Psychiatric Genomics Consortium (PGC)@pgcgenetics.bsky.social · 4mo ago

📢 New publication in @nathumbehav.nature.com from the PGC Anxiety Working Group: the largest GWAS of generalised anxiety symptoms to date, analysing ~700k across 14 cohorts. We found 74 genome-wide significant loci, 39 novel for anxiety.

📢 Our GWAS meta-analysis of anxiety disorders is now published in Nature Genetics! Was a pleasure putting together these posts shared from the @pgcgenetics.bsky.social account to showcase this exciting milestone in anxiety genomics👇

Psychiatric Genomics Consortium (PGC)@pgcgenetics.bsky.social · 8mo ago

🧵 New publication from the PGC Anxiety Working Group. Our GWAS meta-analysis of anxiety disorders is now published in @natgenet.nature.com! 🔗: doi.org/10.1038/s415...

Are you looking to learn how to conduct and interpret Mendelian randomization studies? You can register now for our in-person short course at UCL. With @emmylooroll.bsky.social and @dylwil.bsky.social 16th-18th September 2025. Details here: www.ucl.ac.uk/brain-scienc...

Mendelian randomization short course

This course covers the fundamental developments in Mendelian randomization and gives practical explanations about how to apply MR to applied research questions.

ucl.ac.uk

Pleased to share our new preprint on the 1st large-scale GWAS meta-analysis of panic attacks and panic disorder 👇

Gerome Breen@psychgenomics.bsky.social · last yr.

Excited about our new preprint: 1st successful genome-wide study of >61,000 panic attack and 29,000 panic disorder cases. www.medrxiv.org/content/10.1... We find 17 associations & evidence that peripheral neurons in eye, lungs and heart are involved in panic & other psychiatric disorders 1/n

That’s a wrap for the #MDD & #Anxiety takeover, thanks for joining us! Special thank you to Outreach Committee Liaisons @karmelchoi.bsky.social (MDD) & @abiterkuile.bsky.social (Anxiety) and all post contributors.

Check out our new paper on the second UKB mental health questionnaire! Was a pleasure to work on the coding team (incl. new additions of panic disorder & panic attack algorithms with @megsk.bsky.social). Thanks for leading @katrinadavis.bsky.social & coding lead @jonicoleman.bsky.social!

Joni Coleman@jonicoleman.bsky.social · last yr.

Very pleased to see our paper describing the @ukbiobank.bsky.social second online mental health questionnaire has now been published in @plosone.org! This describes the origin of the resource as well as the data. Fantastic work by Katrina Davis in leading this 👏👏👏 dx.plos.org/10.1371/jour...

Thanks also to the coding team (see next bleet) who put together the algorithms for this work, which can be found here: github.com/ColemanResea... (as well as a mirror on the DATAMIND GitHub) (RAP-friendly implementation is a work in progress...!)

GitHub - ColemanResearchGroup/MHQ2: Code for deriving phenotypes from the second Mental Health Questionnaire in UK Biobank

Code for deriving phenotypes from the second Mental Health Questionnaire in UK Biobank - ColemanResearchGroup/MHQ2

github.com

2/n Which #anxiety disorders were included & how were they measured? ✅ 5 major anxiety disorders: ‘any anxiety’ approach captures shared genetics across disorder cluster 📝 Anxiety can be measured in different ways: tested heterogeneity across assessment methods & found strong genetic overlap

Live from the conference continues, we are now at 98 club karaoke, first come first serve! @essgn.bsky.social