🚨 New Trial Spotlight The Do IT Study found that in people with HIV and obesity, switching from an INSTI + TAF/FTC regimen to DOR/FTC with either TAF or TDF did not produce clinically meaningful differences in weight change. 📖 Read the study: academic.oup.com/cid/article/...

A 48-Week, Randomized Controlled Trial of Doravirine for Individuals With HIV and Obesity on Integrase Inhibitors and Tenofovir Alafenamide: The Do IT Study (ACTG A5391)

The prospective, randomized, multicenter A5391 trial found that switching from INSTI- and TAF-containing antiretroviral therapy to an NNRTI, with or withou

academic.oup.com

August is National Immunization 💉 Awareness Month 📆 Vaccines help your body 🏋️ build immunity and protect against many preventable diseases 🦠 😷 #AIgenerated

ICYMI, a retrospective study published in AJHP last month found higher rates of 1-hour sepsis bundle completion, particularly the timely administration of antibiotics ⏱️💊, when a pharmacist was on the responding team 💪 📖 academic.oup.com/ajhp/advance... #Sepsis

Impact of pharmacist involvement on hospital sepsis response teams

AbstractPurpose. Data describing the impact of pharmacists on early sepsis management performed by multidisciplinary sepsis response teams are limited to t

academic.oup.com

The European Respiratory Society and ESCMID released a statement on the role of rapid diagnostic tests in community-acquired lower respiratory tract infections🫁, providing plenty of time to plan approaches for the respiratory season! 🔗https://www.cmi-comms.org/article/S2950-5909(26)00027-2/fulltext

Join @accpinfdprn.bsky.social and the Critical Care PRN to learn 💻 more about beta-lactam💊 TDM 🧪 in the ICU🏥 Register at the ACCP events page : accp.com/prns/events/...

Hot on the heels of the IDSA 2026 treatment of AMR Gram-negative infections update is a retrospective cohort study that compared mortality in hypoalbuminemic patients who received ertapenem versus other carbapenems, finding no difference 📖Read more here: academic.oup.com/cid/advance-...

Absence of Significant Interaction Between Serum Albumin Level and Carbapenem Type on 30-Day Mortality in ESBL-positive E. coli and K. pneumoniae Bacteremia: A Multicenter Cohort Study with Inverse Pr...

In this multicenter study, IPTW analysis revealed no significant interaction between serum albumin and carbapenem type regarding 14-day and 30-day mortalit

academic.oup.com

Knowledge is key to eliminating viral hepatitis. This #WorldHepatitisDay, explore IDSA resources to strengthen hepatitis diagnosis, treatment and patient care with HCV guidance, HBV recommendations, CME/MOC modules and more. Learn more: https://bit.ly/4dqInEj

🚨New IDSA Guidance Alert 🚨 The IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections was updated today, incorporating new evidence and FDA-approved options into its recommendations 💊 See the details here: www.idsociety.org/practice-gui... #IDSA #AMR

AMR Guidance

This updated IDSA AMR Guidance document provides treatment suggestions for infections caused by extended-spectrum β-lactamase–producing Enterobacterales (ESBL-E), AmpC β-lactamase–producing Enterobact...

idsociety.org

The Dutch Guideline on the Management of Community-Acquired Pneumonia in Hospitalized Adults was updated this week 🫁 They align with ATS's recommendations on use of shorter courses, lung ultrasound, and corticosteroids 💊 Read the full publication here: www.cmi-comms.org/article/S295...

Is cefiderocol really the GAME CHANGER in resistant Gram-negative 🦠 infections❓🤔 This review 📜 summarizes RCTs data and real-world 🌏 evidence: 🔗 journalofinfection.com/article/S016...

Cefiderocol in clinical practice: from randomised trials to real-world evidence in the management of multidrug-resistant Gram-negative bacterial infections

Multidrug-resistant Gram-negative bacteria (MDR-GNB) represent a major global health threat, with limited therapeutic options and high morbidity and mortality. Cefiderocol, a novel siderophore…

journalofinfection.com

Learn about infections in patients🏥 with CSF shunts 🧠‼️ State-of-the-art review📜 🆕 incorporating multidisciplinary perspectives from ID 🧫, neurosurgery 🧠 and pharmacy 💊 : 🔗 academic.oup.com/cid/article/...

Effective ARTs 💊 have revolutionized care of patients 🏥 living with HIV🦠 Hot off the press! ♨️ 🆕 Review of Antiretroviral Agents in @NEJM 🔗 nejm.org/doi/full/10....

Antiretroviral Therapy | NEJM

The development of effective treatment strategies for human immunodeficiency virus (HIV) infection is a major achievement. Antiretroviral drugs inhibit key steps in the viral replication cycle and ...

nejm.org

Join @accpinfdprn.bsky.social and the Critical Care PRN to learn 💻️ more about beta-lactam💊 TDM 🧪 in the ICU🏥 Register at the ACCP events page : www.accp.com/prns/events/...

Stay up-to-date 🌟 on the COVID-19🦠 vaccine 💉 landscape‼️ Join IDSA's next Bartlett webinar 🖥️ to learn more about current evidence 📰 on vaccine💉 hesitancy, co-administration opportunities, and insights into immune responses 🩸. 🔗 Sign up here: societycentral.zoom.us/webinar/regi...

How do you use procalcitonin 🧪 in your practice❓️ 🌟 Excellent commentary 💬👍️ Negative procalcitonin most useful in helping anxious clinicians 🧑‍⚕️ 🏥 avoid unnecessary antibiotics 💊 🔗 jamanetwork.com/journals/jam...

Procalcitonin—An Enigmatic Anxiolytic Biomarker

Critics of procalcitonin have questioned its clinical usefulness because of its modest sensitivity and specificity for distinguishing bacterial infections from other diseases. But the diagnostic…

jamanetwork.com

Pharmacists at the center of patient safety & health care quality 🏥👩‍⚕️👨‍⚕️ ID PRN member, Dr. Elizabeth Covington, implements a pharmacist-led initiative to review pending ID results 🧪after discharge 🏡 ⬆️appropriateness of outpatient Rx ⬇️time to appropriate Rx

❓Are ID consult recommendations always adhered to at your institution❓ Maybe it depends on the wording... 🗒️ New study📜 showed that ambiguous wordings were common in ID consult notes 🗒️and could⬇️adherence to recommendations 🏥🩺 🔗https://doi.org/10.1093/cid/ciag400 #IDXposts

Reconsidering ambiguous language in infectious disease consult recommendations

In this retrospective study of 1087 Infectious Diseases consultation recommendations at a multi-site health network in Australia, ambiguous language occurr

doi.org

ORAL carbapenem👄💊approved by the FDA!✅🇺🇸 for cUTIs 🫘 Tebipenem: ✅ESBLs, ❌limited activity against Pseudomonas 🔗https://jamanetwork.com/journals/jama/fullarticle/2851693

‼️ID PRN Members‼️ ACCP is spotlighting PRN initiatives & stories that demonstrate progress in reducing preventable medication harm. Use the link at any time to highlight yourself or another ID PRN member’s initiatives or “great catch” events 👏

♨️Hot off the press! 📜American Gastroenterological Association (AGA) Clinical Practice Guideline on C. difficile 🦠💩 🥇FDX favored, VAN is "also acceptable" 🥈VAN prophylaxis not advised 🥉No need to DC PPI if legitimate indication 🔗https://www.cghjournal.org/article/S1542-3565(26)00358-7/fulltext

Are you attending the AACP Pharmacy Annual Meeting? 🤝🧑‍🏫 Join your fellow ID pharmacists & colleagues for a meet and greet at the Silver Bar inside the Gaylord Texan Resort and Convention Center on July 20th, 2026 🗓️. We hope to see you there!

📢 Penicillin allergy ≠ no cefazolin. More evidence to support cefazolin for most patients with reported β-lactam allergies undergoing surgery. 💉 Let’s move beyond outdated allergy labels and improve patient care! 🦠 academic.oup.com/ajhp/advance... #IDTwitter #AntimicrobialStewardship

Congratulations to all the ID PGY2 resident graduates! Let’s welcome them to the profession and the #IDPRN family by posting your graduation pictures! #happygraduation #infectiousdiseases #antimicrobialstewardship #newgrads

DYK?🦠 Antibiotic-related microbiome disruption may persist long after therapy completion. An observational study in 14,979 adults found that antibiotic use was associated with persistent gut microbiome alterations up to 8 years later. #WorldMicrobiomeDay 📖 doi.org/10.1038/s415...

Looking for a new antimicrobial stewardship metric? 👀 Authors from the VA have proposed a new "S3" option, which assesses the initiation, spectrum, and duration of therapy. 📖 Read more here academic.oup.com/cid/advance-... #AntimicrobialStewardship

Although we'll want to wait for the full results to draw conclusions, interim CAMEL 🐫 study data found similar outcomes with Avycaz and Vabomere for KPC-producing CRE 🦠 bloodstream infections and pneumonia 🫁: pharmacypracticenews.com/a/HzsBAA/t #pharmacy

Two recently published RCTs (academic.oup.com/cid/advance-... and www.ijidonline.com/article/S120... support oral fosfomycin step-down therapy for ESBL cUTIs. Will these papers change your practice? 🤔

JAMA recently published a quick overview of #Vibriosis 🦪🦐🐟 Read the full article here: ja.ma/4ab7Bpx

Vibriosis

This JAMA Insights discusses vibriosis, an infection with noncholera species of Vibrio, including its clinical presentation and diagnosis, risk factors, and effective treatments.

ja.ma

Aw🫰SNAP🫰 Cefazolin vs anti-staphylococcal PCN ⬇️⬇️⬇️

Antibiotic Steward 🅱️C🆔🅿️🌟@absteward.bsky.social · 2mo ago

🔥Just published 🔥NEJM SNAP RCT In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky www.nejm.org/doi/full/10....

🔥Just approved 🔥 The FDA has approved Utebzi (tebipenem pivoxil) tablets as the first oral carbapenem therapy for adults with complicated urinary tract infections, including pyelonephritis #idsky #EMIMCC www.fda.gov/drugs/news-e...

FDA approves first oral carbapenem therapy for complicated urinary tra

FDA approves first oral carbapenem therapy for complicated urinary tract infections

fda.gov