Adam Glaser
@adamkglaser.bsky.social
Developing hardware + software tools for large-scale imaging at the Allen Institute for Neural Dynamics
New 105 MP Sony IMX927 sensor (global shutter) capable of streaming data at 100 fps... 10.5 gigavoxels/sec. www.sony-semicon.com/en/products/...
High Resolution, High-speed, 105 MP & 100 fps Global Shutter Image Sensor | Products & Solutions | Sony Semiconductor Solutions Group
Sony Semiconductor Solutions Group develops device business which includes Micro display, LSIs, and Semiconductor Laser, in focusing on Image Sensor.
sony-semicon.com
Latest imaging data from our completely re-designed ExA-SPIM system. Expansion-assisted imaging (3X expansion, 0.3 NA) enables brain-wide imaging with high-contrast and <400 nm effective resolution.
First 3200 MP images from the LSST at the Vera C. Rubin Observatory! www.nature.com/articles/d41...
First images from world’s largest digital camera leave astronomers in awe
The Rubin Observatory in Chile will map the entire southern sky every three to four nights.
nature.com
High-throughput line scanning confocal microscopy www.biorxiv.org/content/10.1...
A parallelly distributed microscope and software system for scalable high-throughput multispectral 3D imaging
Recent advances in high throughput optical microscopy have achieved whole-organism scale imaging at diffraction-limited resolutions. Current microscopes, however, require making compromises between ac...
biorxiv.org
We are excited to share our development of a new 10X lens with NA=0.50 over a 7.2 mm FOV and a 35 mm working distance (water), fully corrected from 400-850 nm. This lens will power our upcoming ExA-SPIM "2" and is available for dissemination - please get in touch if interested!
Looking forward to the @mesospim.bsky.social #lightsheet #Microscopy anniversary symposium in October with @preibischs.bsky.social @adamkglaser.bsky.social @christellelangevin.bsky.social & many more! And to the next mesoSPIM decade! 🔬 Thanks @nvladimus.bsky.social & Co for organizing it!
To look into: a Python alternative to ZEMAX... github.com/HarrisonKram...
GitHub - HarrisonKramer/optiland: Comprehensive optical design, optimization, and analysis in Python, including GPU-accelerated and differentiable ray tracing via PyTorch.
Comprehensive optical design, optimization, and analysis in Python, including GPU-accelerated and differentiable ray tracing via PyTorch. - HarrisonKramer/optiland
github.com
New review out on imaging 3D cell cultures. Congratulations to Huai-Ching and @jonliu123 on leading this excellent new review! www.nature.com/articles/s41...
Imaging 3D cell cultures with optical microscopy - Nature Methods
This Review discusses current 2D and 3D microscopy methods for imaging three-dimensional cell cultures and emerging strategies to address key challenges.
nature.com
Curved light-sheet microscopy www.nature.com/articles/s41...
Curved light sheet microscopy for centimetre-scale cleared tissue imaging - Nature Photonics
Light sheet microscopy with curved light sheets enables tiling-free imaging of an entire intact cleared mouse brain with lateral and axial spatial resolutions of 1.0 μm and 2.5 μm, respectively, in le...
nature.com
Thermal Lensing Effects in Light-Sheet Microscopy arxiv.org/abs/2504.02969
Thermal Lensing Effects in Two-Photon Light-Sheet Microscopy
In light-sheet fluorescence microscopy (LSFM), the axial resolution is governed by the illumination beam profile, motivating the development of advanced beam-shaping techniques to enhance imaging perf...
arxiv.org
Sound-sheet microscopy - in this study, we introduce nonlinear sound-sheet microscopy (NSSM), a method to image targeted biological functions across cubic centimeters of opaque living tissue. www.science.org/doi/10.1126/...
Nonlinear sound-sheet microscopy: Imaging opaque organs at the capillary and cellular scale
Light-sheet fluorescence microscopy has revolutionized biology by visualizing dynamic cellular processes in three dimensions. However, light scattering in thick tissue and photobleaching of fluorescen...
science.org
Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue www.biorxiv.org/content/10.1...
Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue
Light sheet microscopy is the ideal technique for multiscale imaging of large and cleared tissues, and it is desirable to achieve the highest possible isotropic resolution across the entire sample. Ho...
biorxiv.org
New 410 MP camera sensor coming in 2025 from Canon global.canon/en/news/2025...
Canon develops CMOS sensor with 410 megapixels, the largest number of pixels ever achieved in a 35 mm full-frame sensor | Canon Global
TOKYO, January 22, 2025—Canon Inc. announced today that it has developed a CMOS sensor with 410 megapixels, which is the largest number1 of pixels ever achieved in a 35 mm full-frame sensor.
global.canon
