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Sasha Larsen Akins

@akinssasha.bsky.social

Seattle scientist studying immunology, vaccines and phages for TB in clinical trials and preclinical models - (she/her)

3 Posts56 Follower128 Folgt
Sasha Larsen Akins@akinssasha.bsky.social · 2y ago

Excited about progress we are making to build a system for preclinical interrogation of #phages for #Tb #TBSKY virologyj.biomedcentral.com/articles/10....

Evaluation of host immune responses to Mycobacteriophage Fionnbharth by route of delivery - Virology Journal

For much of the last decade, tuberculosis (TB) was the leading cause of mortality due to an infectious pathogen (Mycobacterium tuberculosis, M.tb). Approximately 1.3 million deaths in 2023 worldwide w...

virologyj.biomedcentral.com

Sasha Larsen Akins@akinssasha.bsky.social · 2y ago

Really fortunate to have worked with Hannah Painter on this story where she put up with my shenanigans > 3 years + Mat leave. We mused on whether human derived COR biosignatures could be used in preclinical models - turns out - it depends! #TBSky pubmed.ncbi.nlm.nih.gov/39651886/

Backtranslation of human RNA biosignatures of tuberculosis disease risk into the preclinical pipeline is condition dependent - PubMed

Understanding the strengths or limitations of back-translating human-derived correlate of risk (COR) RNA signatures into the preclinical pipeline may help streamline down-selection of therapeutic vacc...

pubmed.ncbi.nlm.nih.gov

Hetan Shah@hetanshah.bsky.social · 2y ago

Fancy a new job? How about £200k to be Associate Director for Strategy at Wellcome? Interesting cross cutting role in this London based global health foundation wellcome.wd3.myworkdayjobs.com/en-US/Wellco...

Associate Director, Strategy

Salary: £200,000 per annum Contract: Permanent Closing date: 6th December Wellcome is a global charitable foundation. We improve health for everyone by investing in research, developing policy and par...

wellcome.wd3.myworkdayjobs.com