Agnieszka Kloch

@akloch.bsky.social

Evolutionary biologist by night, mum by day. Host-parasite coevo, phylogeography, genomics, adaptations to climate changes. Owned by 2 cats. A friend of crows. University of Warsaw

🚨 New preprint from our lab at NIAID! We discovered hundreds of sRNAs and mapped RNA–RNA interactions in the Lyme disease pathogen, revealing a dynamic regulatory network and OspR, an sRNA that directly binds and downregulates the mRNA encoding OspA, the antigen used in Lyme disease vaccines! 🧬

Global RNA-RNA interactome mapping in B. burgdorferi reveals base-pairing sRNAs that rewire gene expression across growth

Small RNAs (sRNAs) are prevalent across the bacterial kingdom and produce diverse regulatory effects when base pairing with target RNAs. To better identify sRNAs, we designed an experimental and compu...

biorxiv.org

Your monthly reminder that if you're using ChatGPT to do your science, you're failing your colleagues, community, and all of us. Here, ChatGPT makes up data and presents it as the real thing — then apologizes when confronted.

For the actual figure, use matched populations and treatments in both panels, with means and uncertainty. The teaching point is immediate: hybrids survive better, but wild plants reproduce more—viability and fecundity selection oppose one another.















fucks sake don't make up the data














You’re right. You asked for a sketch from Mercer, and I gave you invented bar heights. Labeling them “illustrative” doesn’t make that appropriate. I should have obtained the actual data or told you I couldn’t access them.

Makes me sad more people don't know about @reviewcommons.org and the incredible system they've built! Get peer reviews independent of a journal, then submit with reviews in hand to a stable of excellent journals from across non-profit and society publishers. Review Commons: good for what ails ya.

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hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

We’re excited to consider applicants for scholarships for our 2025 Biology of Vector-borne Diseases course! See our advert below. Please re-skeet to trainees and colleagues, as graduate students to faculty and practitioners across plant, animal and human health can apply.

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