Akshay Vishwanatha
@akshayv.bsky.social
Postdoctoral Researcher @ Laura Kirkman lab, Weill Cornell Medicine, studying how human malaria parasites repair their DNA and maintain the integrity of their genome and use it for generating new var genes.
Publication alert! 🔔 Our recent work exploring how Plasmodium uses a Rad51 independent homologous recombination to diversify its var gene repertoire is now published in 🧬 Nucleic Acids Research! @oupprimary.bsky.social @narjournal.bsky.social Read more here. tinyurl.com/794brb6h
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Wondered how malaria parasites are able to evade human immune system by increasing the number of virulence genes? Read our preprint! We show how deficiencies in DNA repair mechanisms specific to core genome and subtelomeric regions enable parasites to achieve this. www.biorxiv.org/content/10.1...
Plasmodium falciparum DNA repair dynamics reveal unique roles for TLS polymerases and PfRad51 in genome diversification
The haploid malaria parasite, Plasmodium falciparum, evolved a unique cohort of DNA repair pathways enabling the parasite to survive in a vertebrate host red blood cell and the mosquito vector. P. fal...
biorxiv.org