Alba Moreno Pérez
@alba-mp.bsky.social
Postdoctoral Scholar in Coaker Lab at UC Davis. I am studying plant immune responses during plant-microbe interactions.
TALEs, TALENs, and TALE Base Editors: From Plant Pathology to Biotechnology www.annualreviews.org/content/jour... #PlantResearch #PlantScience #PlantSci #PlantBiology
TALEs, TALENs, and TALE Base Editors: From Plant Pathology to Biotechnology
TALEs (transcription activator-like effectors) are an excellent example of how studying pathogen–host interactions can lead to significant biotechnology inventions. TALEs are bacterial effectors that ...
annualreviews.org
So proud to share our latest publication @CellCellPress! Yue Rui reveals that the same enzyme that makes the wall, cellulose synthase complex (CESA), also tethers the plasma membrane to the wall during water-deficit stress, providing resilience. sciencedirect.com/science/articl…
Announcing our new free Webinar series sponsored by GetGenome: Road to Jeju. The series will feature 7 webinars with Legends and Rising Stars of IS-MPMI. Sign up to attend the first talk by Roger Innes on June 17. lnkd.in/gw4pKp4K Rising Star info coming soon. please repost!
Breakthrough discovery in the field of peptide-receptor kinase signaling in stomatal development🌱. Six partially-redundant subtilases producing mature EPF1/EPF2 pepetide to enforce stomatal patterning @natplants.nature.com 🥰 www.nature.com/articles/s41...
Subtilase-mediated maturation of EPF1 and EPF2 is crucial for stomatal patterning - Nature Plants
This study identifies epidermal patterning factor (EPF)-processing proteinases as the key activators of EPF1 and EPF2 peptides, establishing their proteolytic processing as the critical missing link f...
nature.com
Register now for the 2nd webinar in our new series on quantitative plant imaging, hosted by @ajcellbio.bsky.social & @joemckenna.bsky.social. In this webinar we’ll hear from @laurabacete.bsky.social on Brillouin microscopy & @sventruckenbrodt.bsky.social on expansion microscopy. 🗓️16 July, 15:00 BST
Register for FocalPlane features... quantitative plant imaging across scales - FocalPlane
Register for FocalPlane features... quantitative plant imaging across scales - News
focalplane.biologists.com
🌱🔬Save the date for the second webinar in this series: Thursday 16 July at 15:00 BST. Updates will appear on our webpage or you can sign up to our FocalPlane features... mailing list to stay up-to-date with the latest information. focalplane.biologists.com/macro-to-mic...
FocalPlane @focalplane.bsky.social · 3mo agoThe recordings from the first webinar in our new series on quantitative plant imaging are now available. Check out the presentations from Thomas Ott @ottlab.bsky.social (on behalf of Beatrice Lace @blace.bsky.social) and Simon Gilroy: focalplane.biologists.com/2026/05/19/f...
Excited to share new work from us in the @spicybotrytis.bsky.social lab on Botrytis-legume co-transcriptomics. Similar disease phenotypes between your hosts could be masking a ton of underlying transcriptional plasticity 🌱💥 academic.oup.com/g3journal/ad...
In case you missed it, the second Plant Imaging Workshop organized by @plantcellatlas.bsky.social is now available on YouTube: www.youtube.com/watch?v=rytH... In this session, you will learn how to get started with MorphoGraphX to do 2D and 3D segmentation. #plantmicroscopy #plantimaging
Imaging Workshop Webinar Series Part 2: Introduction to 2D and 3D Segmentation with MorphoGraphX
YouTube video by Plant Cell Atlas
youtube.com
New Preprint in collaboration with GoogleDeepMind: AI-guided discovery of atypical protein assemblies The @kamounlab.bsky.social discovered an 11-protomer complex thanks to the Structural Novelty Index , a new way to use AlphaFold to find protein assemblies that break the pattern.
AI-guided discovery of atypical protein assemblies
Artificial intelligence (AI) systems such as AlphaFold have transformed structural biology by enabling accurate prediction of protein structures. However, their capacity to uncover new classes of…
tsl.ac.uk
We are hiring! We’re excited to recruit a postdoc to our lab at UC Davis to work on plant immune engineering and single-cell analyses of plant pathogen interactions. Apply by June 1. Please repost. www.coakerlab.org/postdoctoral...
Excited to share our new preprint! We explore how experimental context influences immune responses triggered by elf18 and flg22 in Arabidopsis. Huge thanks to @gittacoaker.bsky.social for her guidance and support, and to Hanxu Sha for her help on this project. www.biorxiv.org/content/10.6...
Experimental Context Shapes PRR-Mediated Immune Output Sensitivity in Arabidopsis
Pattern recognition receptors (PRRs) mediate plant immune responses by detecting extracellular immunogenic patterns, including microbe-associated molecular patterns (MAMPs). PRR signaling is commonly assessed using assays such as reactive oxygen species (ROS) bursts, cytosolic calcium influx, mitogen-activated protein kinase (MAPK) activation, and seedling growth inhibition (SGI), which are performed in distinct experimental systems, including seedlings grown on artificial media and soil-grown rosettes. Here, we systematically compare receptor kinase immune outputs triggered by the bacterial MAMPs elf18 and flg22 in Arabidopsis thaliana seedlings and rosettes across a range of concentrations. Rosettes exhibited greater sensitivity than seedlings in ROS assays, whereas cytosolic calcium responses measured using the Aeqcyt/pMAQ2 reporter were stronger in seedlings, correlating with reduced reporter transcript accumulation in rosette tissue. MAPK activation was consistently stronger in rosettes, whereas SGI assays revealed higher sensitivity to elf18 than flg22 in seedlings despite flg22 inducing stronger early signaling outputs. Together, these results demonstrate that canonical PRR-mediated immune outputs are differentially sensitive to experimental context and should not be interpreted as interchangeable measures of immune activation. These findings highlight the importance of considering experimental conditions when comparing immune responses across assays and developmental stages. ### Competing Interest Statement The authors have declared no competing interest. National Institutes of Health, https://ror.org/01cwqze88, R35GM136402 Fundación Alfonso Martín Escudero, https://ror.org/02897ye82
biorxiv.org
Our review on disease resistance gene diversity in Triticeae is finally online 🌾🌾! Gained so many insights writing it with Yinghui Li & Liubov Govta and from the guidance of gittacoaker.bsky.social & Tzion Fahima. Fascinated by plant resistance gene diversity—excited to share!
The Spectrum of Diverse Disease-Resistance Genes Cloned and Characterized in the Triticeae Tribe | Annual Reviews
The Triticeae tribe comprises species representing some of the world's largest food and forage crops, including common wheat, durum, barley, rye, and oat. Crop yields are continuously threatened ...
annualreviews.org
Gitta Coaker@gittacoaker.bsky.social · 11mo agoHappy to share this review on the diversity of resistance in Triticeae. I learned a lot writing it. Heavy lifting by Yinghui Li, Liubov Govta, and @yichangsung.bsky.social with our long-time collaborator Tzion Fahima. www.annualreviews.org/content/jour...
Our new paper is out in New Phytologist! We describe how the Ralstonia solanacearum effector RipAV suppresses plant immunity by directly interfering with key defense regulators. 🧵👇 nph.onlinelibrary.wiley.com/doi/10.1111/...
The Ralstonia solanacearum effector RipAV targets plant U‐box proteins and induces proteasomal‐dependent degradation of BIK1
Plants have developed a complex immune system to detect and respond to invading pathogens. A critical aspect of this defense relies on regulatory mechanisms that control the activation of immune res...
nph.onlinelibrary.wiley.com
Big news from the Demirer lab: first 4 research papers are preprinted! Check them out, feedback welcomed: eCIS for plant protein delivery: tinyurl.com/mrx4d878 R2 for targeted insertion: tinyurl.com/5n73za6h Transient expression: tinyurl.com/38p2ud6w Chemotaxis assay: tinyurl.com/3nw9haes More ⬇️
How can we better understand the plant immune system? In my new @cp-cellhostmicrobe.bsky.social piece, I propose “immune cell states” as a framework for uniting molecular and cellular perspectives. www.cell.com/cell-host-mi...
Don't miss this awesome work of @yichangsung.bsky.social on plant tandem kinases (TKPs)!!
Gitta Coaker@gittacoaker.bsky.social · last yr.I'm very excited our most recent work on plant tandem kinases (TKPs) has finally been published! TKPs are a fascinating protein family conferring disease resistance to fungi. Originally in bioRxiv. Many thanks to @yichangsung.bsky.social for leading this work. 🧵 www.nature.com/articles/s41...
Happy to share our paper from a new research line led by @camolsan.bsky.social, where we engineered the T6SS of Pseudomonas putida to deliver effectors against bacterial competitors and fungal pathogens like Botrytis cinerea. @ihsmumacsic.bsky.social jbioleng.biomedcentral.com/articles/10....
Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors - Journal of Biological Engineering
Background Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine...
jbioleng.biomedcentral.com
nph.onlinelibrary.wiley.com/doi/10.1111/...
Orchestrating ROS regulation: coordinated post‐translational modification switches in NADPH oxidases
Reactive oxygen species (ROS) are among the most important signaling molecules, playing a significant role in plant growth, development, and responses to various environmental stresses. Respiratory b...
nph.onlinelibrary.wiley.com
Thrilled to see this out! 🎉 doi.org/10.1111/pbi.... 🌿🧬 Silencing immunity genes boosts transient expression in Nicotiana benthamiana! Congrats to all involved! A #PlantChemetics story first on @biorxivpreprint.bsky.social, now in @PlantBiotechJ. #TransientExpression #MolecularPharming
Immunity gene silencing increases transient protein expression in Nicotiana benthamiana
Click on the article title to read more.
doi.org
Happy to share a new preprint from the lab. We compared Nanopore long reads to Illumina short reads for use in assembly and population-level variant calling and genotyping. We were surprised by which approaches and pipelines were most accurate. www.biorxiv.org/content/10.1...
A comparison of short- and long-read whole genome sequencing for microbial pathogen epidemiology
Whole genome sequencing provides the highest resolution for characterizing pathogen evolution, epidemiology, and diagnostics. Genome assemblies contain information on the identity and potential phenot...
biorxiv.org
🚨 We’re hiring–please spread the word! 🚨 Our lab at @thesainsburylab.bsky.social is looking for a pre-doc intern to join our research on plant immunity. If you’re a current undergrad/master’s or recent graduate interested in gaining research experience, please apply! tatsuyanobori.com
The Sainsbury Laboratory@thesainsburylab.bsky.social · last yr.VACANCY: Predoc Internship Nobori Lab, UK Plant immunity research at single-cell & spatial resolution Interested in pursuing a PhD or developing your research skills in plant & microbial science? Apply online, position may fill after 24/03 ➡️ www.tsl.ac.uk/working-at-t... @tatsuyanobori.bsky.social
Yes, well done 👏. The team shows that there are distinct bacterial populations that affect leaf growth of young leaves and repress plant defense genes. They also include a section on limitations of the study. All papers should include such a section, please.
Germán Bonilla-Rosso@germusthermophilus.bsky.social · last yr.🦠🧫🌱🌍🧬🖥🧪 WOW! Really impressive and convincing work shows that leaf microbiota modulated tradeoff between defense and growth of leaves in maize! Good to see research that has no need to oversell microbiota effects! www.sciencedirect.com/science/arti...
📜 Transformation of flg22 perception into electrical signals decoded in vasculature leads to sieve tube blockage and pathogen resistance 🧑🔬 @furch-lab.bsky.social, Aart J. E. van Bel, et al. 📔 Science Advances 🔗 www.science.org/doi/10.1126/... #️⃣ #PlantScience #PlantImmunity #PlantSignaling
Transformation of flg22 perception into electrical signals decoded in vasculature leads to sieve tube blockage and pathogen resistance
Flg22-triggered dual electric signals are crucial for generation of local and systemic defense responses.
science.org
very interesting to hear RARE also in P-bodies
Şuayb Üstün@suaybuestuen.bsky.social · last yr.Cool new paper by @jonathandgjones.bsky.social and colleagues how #proteostasis modulates NLRs - Interestingly, we identified RARE as a new P-Body component in our recent #preprint 🤓 www.biorxiv.org/content/10.1...
(1/3) Plant pathology and agroeconomics - the #PlantScience in this week's @science.org: Plant-derived phytoalexin, erucamide, blocks the bacterial type III secretion system to enhance plant defence www.science.org/doi/10.1126/...
A widespread plant defense compound disarms bacterial type III injectisome assembly
Numerous gram-negative bacterial pathogens employ the type III secretion system (T3SS), a multiprotein injectisome, to deliver virulence proteins into host cells and cause diseases. We uncover erucami...
science.org
Thrilled to make my first post on Bluesky! Even more excited to be presenting today at the IS-MPMI Early Career Showcase alongside an amazing lineup of speakers. Don’t miss this opportunity—join us! @ismpmi.bsky.social www.ismpmi.org/Events/2025-...
2025 Early Career Showcase
......2025 Early Career Showcase...Registration NOW OPEN!Join the 2025 Early Career Showcase: A Global Gathering for Advancing Plant-Microbe Research Explore new breakthroughs in plant...
ismpmi.org
