Marc Somssich

@somssich.bsky.social

Plant Scientist R&D Trait Program Manager (Biotic Stress) @KWSGroup.bsky.social Web: https://linktr.ee/somssich Personal Account

I don't think he objects to post-writing editing, but the key point is that the ideas have to come from the human brain. Not only because our ideas are better, but also because "use it or lose it". Especially for early career folk, writing is the ultimate test of your ability to think & synthesize.

PhD Opportunity at Clemson University! Join our lab to develop cutting-edge AI methods for gene regulatory network inference from single-cell multi-omics data. Research areas include PU Learning, MIL, Flow Matching, and GFlowNets at the intersection of AI and single-cell. Contact me and please RT

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Attention Nicotiana benthamiana users! Certain strains of Agrobacterium (e.g. GV3101-pMP90) induce glandular trichomes because of cytokinin production by Agrobacterium. As this can influence assay outcome, we recommend testing several strains. See our preprint: www.biorxiv.org/content/10.1...

Cytokinin-mediated trichome initiation in Nicotiana benthamiana upon Agrobacterium tumefaciens infiltration

Infiltration of Agrobacterium tumefaciens in leaves of Nicotiana benthamiana has become a standard method for transient expression in plants. Like many Solanaceae species, N. benthamiana develops on i...

biorxiv.org

Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...

Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS

In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...

pnas.org

Breaking news: Shanghai Jiao Tong University School of Medicine will launch a “comprehensive investigation” into the previously undisclosed death last year of a 6-year-old girl who had received an experimental gene therapy from one of its scientists. Learn more: https://scim.ag/4yJXPoU

Chinese university launches probe into girl’s gene-editing death
More than a year after failed clinical trial, Shanghai Jiao Tong University School of Medicine promises “serious action”

“Seven days after the girl’s medical team infused trillions of viruses carrying the recipe for the base editor into her spinal fluid, she died of a severe immune reaction linked to the therapy…” This, in @science.org, is an important and tragic story. (It’s also an incredibly well reported one.) 🧪

Exclusive: Death of girl in Chinese gene-editing trial was never made public

Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals

science.org

13. Hence our dismal conclusion: rather than finding that LLMs free us to do a better job of what we were doing before they came along, they shift scientific incentives (and the playing field of academic competition) in ways that compel us to do more and more, faster and faster, less and less well.