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Coalition for Aligning Science

@aligningscience.com

The Coalition for Aligning Science (CAS) designs and implements large-scale research programs that address unmet needs and maximize impact in biomedical research. www.aligningscience.com

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Coalition for Aligning Science@aligningscience.com · last wk.

Information needs to be collected and shared to have a meaningful impact. The power of our @wastewaterscan.bsky.social initiative is proof of that. Read more in Medical Daily about how WastewaterSCAN is being used to monitor the rising Nimbus variant: https://medicaldaily.pulse.ly/l9mu4kp8tf

COVID Nimbus Variant Now Leads the U.S. as Cases Grow in 27 States and Emergency Visits Rise

COVID Nimbus variant NB.1.8.1 now accounts for 43% of U.S. cases. CDC models show growth in 27 states. ER visits rising. What high-risk people need to do now.

medicaldaily.pulse.ly

Coalition for Aligning Science@aligningscience.com · last wk.

"1817 was the year we gave Parkinson’s a name. 2026 is the year we finally dismantle it." - Dr. Sonya Dumanis, Chief Opperating Officer, CAS

Aligning Science Across Parkinson's (@asapresearch.parkinsonsroadmap.org)

Parkinson’s is not one disease, and treating it as one may limit progress. In Bio-IT World, ASAP Managing Director and @aligningscience.com COO Sonya Dumanis, PhD, explores how biomarkers, molecular stratification, and open science can move the field toward precision medicine. 🔗: bit.ly/4hzVKWw

bsky.pulse.ly

Coalition for Aligning Science@aligningscience.com · 2w ago

Our research initiative has released a new training video playlist to help scientists maximize the CRN Cloud—a powerful hub now featuring over 50 harmonized datasets spanning transcriptomics, lipidomics, and proteomics. Watch the videos to learn more:

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 2mo ago

🎥 Check out a new CRN Cloud training video playlist to help researchers navigate the platform, explore available datasets, and begin analyzing shared #Parkinson’s disease omics data. The playlist includes a video on how to perform and share analyses using CRN Cloud datasets: bit.ly/4avLFp9

ASAP CRN Cloud graphic with the ASAP and CRN Cloud logos, headline “New CRN Cloud Training Videos,” and text reading “Explore tools, datasets, and resources to support Parkinson’s disease research.” A subtle branching network/tree illustration appears on the right.
Coalition for Aligning Science@aligningscience.com · 3w ago

The bipolardiscoveries.bsky.social Integrated Network is combining genetic data with deep phenotyping across 1,500 participants to advance insights into bipolar disorder. Hear Dr. Cara Altimus & Dr. Benjamin Neale discuss the research on The Genetics Podcast: bit.ly/3SiTBnj

The Genetics Podcast: EP 243: How BD² is using genetics and deep phenotyping to transform bipolar research with Cara Altimus and Ben Neale

This week on The Genetics Podcast, Patrick is joined by Dr. Cara Altimus, CEO of BD², and Dr. Benjamin Neale, Associate Professor at Harvard Medical School and Massachusetts General Hospital. They...

bit.ly

Coalition for Aligning Science@aligningscience.com · last mo.

Our @wastewaterscan.bsky.social initiative has expanded its national surveillance framework to track seasonal, enteric, and emerging pathogens—including Influenza A, Hepatitis A, and Mpox. Explore the open dashboard:

WastewaterSCAN@wastewaterscan.bsky.social · 2mo ago

UPDATE! 📣NEW DATA: We now monitor more pathogens in wastewater samples collected from sites across the country. Check out the data: data.wastewaterscan.org #Wastewater #Data #Epidemiology #PublicHealth #Bacteria #Viruses #Fungus #Diseases

Coalition for Aligning Science@aligningscience.com · last mo.

Our CRN teams are helping us pinpoint exactly how, where, and in which cell types Parkinson's disease risk variants operate! Check out the recent preprints and publications! 👇

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 2mo ago

📣 New genomics research from CRN teams examines how genetic risk variants, regulatory networks, and enhancer activity shape cell-type-specific #Parkinson’s disease biology.

Coalition for Aligning Science@aligningscience.com · last mo.

Wondering about the future of #Parkinson's research within GP2? Read the latest blog from ASAP 🧪:

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 3mo ago

🧬 In a new blog, GP2 shares a three-year strategic roadmap, outlining the next phase that expands research beyond genetic discovery to better understand Parkinson’s disease through the study of genetic risk, biological mechanisms, disease subtypes, and environmental factors. 🔗 bit.ly/4eDthMd

Graphic featuring four diagonal panels representing scientific research: a DNA strand, brain imaging scans, laboratory samples being processed with a pipette, and genetic sequencing data. The image is displayed in blue and green tones.
Coalition for Aligning Science@aligningscience.com · 2mo ago

Don't miss this action-oriented guide with a compilation of open science resources for funders and researchers. 🧪

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 3mo ago

Open science is part of how research contributions are recognized, shared, and assessed, making research more reproducible, reusable, & actionable. A new DORA guide for research funders highlights ASAP’s #OpenScience resources & Output Catalog as examples of these principles in use🧪 bit.ly/3RAfEFL

Graphic with a dark background and the headline, “3K+ Resources. One Catalog.” Five circular icons show resource categories and counts: +600 Articles, +400 Datasets, +700 Lab Materials, +1,300 Protocols, and +170 Codes. The Aligning Science Across Parkinson’s logo appears at the bottom.
Coalition for Aligning Science@aligningscience.com · 3mo ago

Mental health is brain health. For Brain Awareness Month, be sure to read this article by @bipolardiscoveries.org Scientific Chair and colleagues about the link between mental illness & neurological disorders: www.statnews.com/2026/04/28/b...

Why do discussions about ‘brain health’ ignore mental illness?

“Failing to adopt a more inclusive concept of brain health represents a massive loss of human potential,” write Husseini K. Manji, Eric J. Nestler, and Patrick J. Kennedy.

statnews.com

Coalition for Aligning Science@aligningscience.com · 3mo ago

Through wastewater monitoring, scientists are tracking more than a dozen infectious diseases across the country. Follow ‪@wastewaterscan.bsky.social‬ for weekly updates on pathogen trends.

WastewaterSCAN@wastewaterscan.bsky.social · 4mo ago

📊 WWSCAN Weekly Data: Respiratory & Gastrointestinal Weekly Update: Nationwide, RSV, HMPV and Rotavirus are in the ‘High’ category. Norovirus is in the ‘Medium’ category. SARS-CoV-2, Influenza A, Influenza B, and EV-D68 are in the ‘Low’ category.🛟😷🧪

Respiratory & gastrointestinal weekly update: Dials showing that respiratory pathogens (RSV and HMPV) are in the high category. Norovirus is in the medium category. The other seasonal pathogens (SARS-CoV-2, Influenza A, Influenza B & EV-D68) are in the low category and not in seasonal onset. The remaining gastrointestinal pathogen (Rotavirus) is in the high category.
Coalition for Aligning Science@aligningscience.com · 3mo ago

“It’s been the single most impactful grant I’ve ever had,” shared Dr. James Hurley of the University of California, Berkeley. Learn how $261 million in new grants for #Parkinson’s disease research is fueling collaboration: www.alzforum.org/news/communi...

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 3mo ago

The Collaborative Research Network is built on team science. A new Alzforum article highlights how CRN investigators are working across institutions and disciplines to advance #Parkinson’s disease research through shared tools, data, and expertise. Read more: bit.ly/4dj8ePI

Graphic with a purple, blue, teal, and green gradient background. On the left, a circular headshot of Sonya Dumanis appears with a white border and decorative white starburst accents. On the right, large white quote text reads, “Our goal is to bring together people with complementary expertise across different institutions and disciplines to answer research questions collaboratively.” Beneath the quote, the attribution reads, “– Sonya Dumanis, PhD, Managing Director of Aligning Science Across Parkinson’s.” The ASAP logo appears in the lower-left corner.
Coalition for Aligning Science@aligningscience.com · 3mo ago

Learn how @bipolardiscoveries.org's philanthropic model is accelerating research and discovery to improve the lives of those living with bipolar disorder.

Inside Philanthropy@insidephilanthropy.com · 4mo ago

The BD2 initiative has been assembling an international network to coordinate research and standards of care. Backers include Sergey Brin and Dalio Philanthropies. Paul Karon Reports: tinyurl.com/467unduf #MentalHealth #Philanthropy #BipolarDisorder #Neuroscience #MedicalResearch #Science

Coalition for Aligning Science@aligningscience.com · 3mo ago

Explore the impact of GP2 and its mission to genotype over 250k volunteers globally in this paper authored by our team!

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 4mo ago

📢 A new paper from @aligningscience.com explores the importance of genetic diversity in Parkinson’s disease research and how GP2 is helping drive new discoveries and precision medicine through global representation and participation. 🔗 Check it out here: bit.ly/4347QyC

People standing across a colorful background with overlapping circles and brain scan images in the center.
Coalition for Aligning Science@aligningscience.com · 4mo ago

🧪 Milestone alert for #bipolardisorder research! Despite advances in neuroscience & psychiatry, progress has lagged. Not because the questions aren’t clear, but because data needed to answer them has been fragmented, inconsistent & too small to scale. BD²’s data release is changing what's possible.

BD²@bipolardiscoveries.org · 5mo ago

Bipolar disorder research has long been slowed by fragmented data. BD²’s first Integrated Network data release helps change that, bringing together rich, longitudinal data to support more connected, collaborative discovery. 🔗See what more connected data unlocks: bit.ly/4tF5f9N

Graphic of rainbow data points over a black background with the white text reading "BD² Integrated Network Data Release" across the center.
Coalition for Aligning Science@aligningscience.com · 5mo ago

Exciting news from @asapresearch.parkinsonsroadmap.org! Collaboration across international teams will address Parkinson's challenges head on in an effort to bring the future of precision medicine closer.

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 5mo ago

📢 Unraveling Parkinson’s. Advancing Precision Medicine. New CRN grants in partnership with The Michael J. Fox Foundation for Parkinson’s Research bring together 32 global teams to map the biology of #ParkinsonsDisease and build tools to accelerate discovery. 🔗 Learn more: bit.ly/4ugkfes

Graphic with a light purple gradient background featuring the headline: “Unraveling Parkinson’s. Advancing Precision Medicine.” Subhead reads: “Mapping the biological blueprint of Parkinson’s disease and building global research resources.” Along the bottom are logos for ASAP (Aligning Science Across Parkinson’s), the Collaborative Research Network (CRN), and The Michael J. Fox Foundation for Parkinson’s Research.
Coalition for Aligning Science@aligningscience.com · 5mo ago

The @asapresearch.parkinsonsroadmap.org Discovery Fellows program is launching the next generation of Parkinson’s researchers. 🧪 It supports bold ideas, gives early-career researchers a network for mentorship and creates an environment where research can thrive: parkinsonsroadmap.org/newsroom/dis...

Inaugural Cohort of Discovery Fellows Aim to Become the Next Generation of Parkinson’s Research

ASAP's Protocols page supports open science by sharing experimental methods that make funded research replicable and useful to the broader scientific community.

parkinsonsroadmap.org

Coalition for Aligning Science@aligningscience.com · 5mo ago

Congratulations to the first cohort of @asapresearch.parkinsonsroadmap.org Discovery Fellows! The future of Parkinson's research is promising with these innovative scientists shaping new approaches. Read about their projects focused on identifying new, actionable targets for therapeutic development:

Aligning Science Across Parkinson's@asapresearch.parkinsonsroadmap.org · 5mo ago

Meet the 2026 ASAP CRN Discovery Fellows 🧪 This fellowship supports early-career scientists as they build independent research programs in #ParkinsonsResearch while developing the next generation of scientific leaders. 🔗 https://bit.ly/4cxE9vz

Graphic with a blue-to-purple gradient background and abstract circular patterns. The text reads: “Introducing the CRN Discovery Fellowship.” Below, it states: “Early-career researchers shaping the future of Parkinson’s research.” The CRN logo appears to the left of the title, separated by a vertical line.
Coalition for Aligning Science@aligningscience.com · 5mo ago

April is world Autism awareness month. Autism is complex and often occurs with epilepsy, mood, sleeping and eating difficulties. ARIA is accelerating scientific discovery for autism through alignment, collaboration, and cutting-edge research. Learn how ARIA plans to make an impact: ariaroadmap.org

ARIA

Aligning Research to Impact Autism is a new initiative that connects emerging research, insights, and promising technologies from across scientific fields.

ariaroadmap.org