This deeper understanding of development in the salamander brain was also foundational for our first study on brain #regeneration, led by @alonso-ortegag.bsky.social, where we show that brain regeneration is not a simple amplification of adult neurogenesis... 🧵5/7 www.biorxiv.org/content/10.6...

Glial cell states bias the regeneration of neuron types across the newt life cycle

Salamanders have outstanding regenerative abilities, which tend to decline in post-metamorphic life stages. Among various tissues, these amphibians can regenerate the brain from ependymoglia cells, an...

biorxiv.org

Very happy to see my PhD work in Biorxiv as of today. I was recently in a talk from @itaiyanai.bsky.social where he talked about his Night Science idea. The talk was already 5 minutes in when it immediately hit too close to home. I had no idea what to make out of this data for so long…

bioRxiv Developmental Biology@biorxiv-devbio.bsky.social · 2mo ago

Glial cell states bias the regeneration of neuron types across the newt life cycle https://www.biorxiv.org/content/10.64898/2026.05.26.728055v1

Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!

Astrocytes connect specific brain regions through plastic networks - Nature

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

nature.com

Excited to share our latest work on brain evolution, where we dive into the evolution of Cajal-Retzius cells! If you are interested in cell type evolution and cerebral cortex evo-devo, please read on… www.biorxiv.org/content/10.1... 🧵 1/7

Evolution of Cajal-Retzius Cells in Vertebrates from an Ancient Class of Tp73+ Neurons

In the developing cerebral cortex, Cajal Retzius (CR) cells are early-born neurons that orchestrate the development of mammalian-specific cortical features. However, this cell type has not been conclu...

biorxiv.org

Post a non-religious photo you think as holy.

Current Biology@currentbiology.bsky.social · 12mo ago

Post a non-religious photo you think of as holy.

Happy to see my PhD work in the Fleischmann lab at Brown University @carneyinstitute.bsky.social published in @natureneuro.bsky.social! -Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution nature.com/articles/s41...