🎄 Warm wishes from María, Alejandra (the artist behind this beautiful art), Álvaro and all the amazing undergraduate students that are part of @ausisgroup.bsky.social. Wishing you all the best! 🙂

It has been a busy end to the year! After attending the SEFAGIA meeting last month, we participated in the @iuopa.bsky.social meeting that took place last week in Corias, Asturias. It was a great opportunity for networking, scientific discussion, and even a little bit of hiking!

📣 ¡Comienza la #SemanaDeLaCiencia de @universidadoviedo.bsky.social (@uodivulga.bsky.social). Estos días estaré impartiendo distintas ponencias divulgativas por Asturias, acercando el mundo de la investigación a las aulas. #FECYT @ficyt.bsky.social @cienciagob.bsky.social @gobasturias.bsky.social

I had the pleasure of attending the @sefagia.bsky.social meeting (#SEFAGIA2025) last week. There, we showcased the advancements of our group, @ausisgroup.bsky.social, in autosis research through a poster presented by Alejandra and a talk given by María.

🗣️ The Spanish Society of Autophagy (SEFAGIA) is holding its 2025 meeting in Miraflores de la Sierra. We’re proud that Miguel Sánchez (#IIBmCSICUAM) has been invited to give a talk. 👏 @sefagia.bsky.social @csic.es @uam.es

⭕️ And here we go! The whole @ausisgroup.bsky.social is on the train to Madrid to attend #SEFAGIA2025. María (talk) and Alejandra (poster) will provide an update on our projects related to autosis. (We are still trying to figure out what @alvfdezfdez-phd.bsky.social will do, such a useless guy!).

SEFAGIA@sefagia.bsky.social · last yr.

⏰ ¡Menos de 24 horas para #SEFAGIA2025! Repasando congresos anteriores: ¡tantas amistades y colaboraciones en estos 12 años! ⏰ Countdown to #SEFAGIA2025! It is a good moment to take a look back at our previous meetings. So many friends and collaborations during these 12 years!

⭕️ Already on my way to #SEFAGIA2025! Eager to meet with so many friends again and learn from all of them over the next three days. By the way, mixed feelings looking at that picture from the first meeting, back in 2013. Good old times, but I miss being in my 20s. 😅

SEFAGIA@sefagia.bsky.social · last yr.

⏰ ¡Menos de 24 horas para #SEFAGIA2025! Repasando congresos anteriores: ¡tantas amistades y colaboraciones en estos 12 años! ⏰ Countdown to #SEFAGIA2025! It is a good moment to take a look back at our previous meetings. So many friends and collaborations during these 12 years!

⭕🗣️ ¡Con muchas ganas de recibir a los ponentes invitados de este año en Miraflores: Robbie Loewith, Marja Jäätelä y Terje Johansen! ⭕🗣️ We are thrilled to welcome our invited speakers Robbie Loewith, Marja Jäättelä and Terje Johansen to Miraflores! #SEFAGIA2025

⭕📣 ¡ #SEFAGIA2025 está a la vuelta de la esquina, y el programa ya está disponible! → orexco.congressus.es/sefagia2025/... ⭕📣 #SEFAGIA2025 is just around the corner, and its programme is already available! → orexco.congressus.es/sefagia2025/...

📺 Esta noche, a las 22:30 y en TPA (canal autonómico del Principado de Asturias), se estrena «Tamos Guapxs», un programa de divulgación científica en el que he tenido el grandísimo honor de participar en varios de sus episodios. Cada martes, un tema nuevo. ¡No os lo perdáis! 😃

✨Nueva edición de la «Noche Europea de los Investigadores e Investigadoras» de @uodivulga.bsky.social (@universidadoviedo.bsky.social) 🎲Estaremos en Gijón (18:00 - 22:00), donde podréis jugar a «La Oca Científica» del @iuopa.bsky.social y aprender sobre la investigación en cáncer. ¡Animaos! 😃

💪 We are back! 🥼 And it is our pleasure to welcome another student from the Bachelor's Degree in Biotechnology: Mariana Álvarez Cuetos, an undergraduate who is full of curiosity and enthusiasm. Welcome! 😃

And thus, the academic year ends. The most challenging and demanding one for me ever, perhaps, given the public examination (along with more than 200 teaching hours, grants, experiments, etc.). Fortunately, @ausisgroup.bsky.social keeps taking exciting small steps forward. See you in a few weeks!

And kudos to Alejandra Piedra Macías for her Master's Thesis, which has launched our search for autotic markers. She will now remain in AU·SIS, where she will continue this project during her PhD! 🥳 Congratulations to both of you! 😀

Once again, it is time to congratulate the students who have successfully completed their Bachelor's and Master's Theses with us! We applaud Miguel Rodríguez Monjardín, who was brave enough to conduct a conceptual study on autosis, proposing new hypotheses for his Bachelor’s Thesis. Well done! 👏

a man with long white hair sits at a table with candles

ALT: a man with long white hair sits at a table with candles

media.tenor.com

🥼 We continue to stay busy in July! This month, Pablo Jiménez, another student from the Bachelor's Degree in Biotechnology, has also joined our group. He is becoming familiar with our projects in preparation for working on his dissertation in the upcoming academic year. Welcome!

Aquí tenéis el divertido pero divulgativo #HiloTesis de @andres-autofagia.bsky.social, investigador predoctoral de nuestro grupo. ¡Bienvenidas/os al mundo de la autofagia! 🙂 (¡Gran trabajo, Andrés! 👏)

Andrés Corrochano Ruiz@andres-autofagia.bsky.social · last yr.

¿Cómo sobreviven tus células cuando se les acumula la basura sin sacar? Os presento a la autofagia, el reciclaje que ayuda a prevenir enfermedades manteniendo el equilibrio celular. #hilotesis @crueuniversidades.bsky.social @filarramendi.bsky.social @uodivulga.bsky.social @iuopa.bsky.social ♻️⚕️

And for an update on autophagy and sleep, check out our review here: www.sciencedirect.com/science/arti... @charlotteboccara.bsky.social @arcticautophagy.bsky.social @cancelluio.bsky.social

Rest, Repair, Repeat: The Complex Relationship of Autophagy and Sleep

Autophagy and sleep are two evolutionary conserved mechanisms across the animal kingdom. Autophagy is a pathway for the degradation of cytoplasmic mat…

sciencedirect.com

www.sciencedirect.com/science/arti... Have a look at our views on the recent paper about fumarate and mitophagy.

Fumarate hits the brakes on mitophagy

In this issue of Molecular Cell, Ham et al.1 demonstrate that the metabolite fumarate, when accumulated in cells, can influence mitochondrial quality …

sciencedirect.com

🥼 In June we are joined by Paula (left), who is studying for a Bachelor's Degree in Medicine, and Víctor (right), pursuing a Bachelor's Degree in Biotechnology. They will be learning basic molecular biology techniques, and we truly appreciate their curiosity! Welcome! 🙂

📣 ¡Arranca #Pint25ES! 📰 Esta noche estaré en el Mala Noche, a las 19 h, para hablar del cáncer, y de cómo se informa sobre él en los medios de comunicación. ¿Son ciertos los titulares que nos llegan? ¡Nos vemos! #Pint25OVD

¡Gracias a todas las personas que os habéis pasado por la Feria! 🔵🟡 Especialmente a las/os peques que se acercaron a jugar y aprender en nuestro espacio. 😃

Álvaro F. Fernández@alvfdezfdez-phd.bsky.social · last yr.

📣 ¡Nueva edición de la Feria de la Ciencia y la Innovación de Asturias! 🧬 Ahí estaremos, por tercer año, para acercar a la gente el mundo de la biología molecular del cáncer y de la investigación. De 10:00 a 14:30 (estudiantes) y de 16:30 en adelante (público general). 🔵🟡

📣 ¡Nueva edición de la Feria de la Ciencia y la Innovación de Asturias! 🧬 Ahí estaremos, por tercer año, para acercar a la gente el mundo de la biología molecular del cáncer y de la investigación. De 10:00 a 14:30 (estudiantes) y de 16:30 en adelante (público general). 🔵🟡

Universidad de Oviedo@universidadoviedo.bsky.social · last yr.

Mañana llega la III Feria de la Ciencia y la Innovación de Asturias. 📢Reserva la mañana y la tarde del viernes🗓️ y acércate a la 📍Nave de Cañones de la Fábrica de Armas de La Vega y descubre las iniciativas innovadoras del personal investigador de la región. https://f.mtr.cool/hhzwjxoxlh

The first milestone of our collaboration with Dr. Vega-Rubín-de-Celis's lab has been completed! Time has flown by, as Dr. Larafa finished her stay with us last week. She has now returned to Germany, along with our own María, to continue our collaboration there. Great initial steps! 🙂

Fun fact: alternative options, such as "trinity", "triplet" and "trio", were also considered at some point. 😅

AU·SIS: Autophagy & autosis@ausisgroup.bsky.social · 2y ago

We are excited to finally share our collaboration with our dear friend Tania, now published in International Journal of Cancer! Our goal was to provide a helpful entry point for readers interested in the connection between autophagy, exosomes, and cancer. onlinelibrary.wiley.com/doi/10.1002/...

Our PKA-autophagy story by outstanding graduate student Ashley Segura (co-led with Rose Citron) published in @embojournal.org, dissects a deep connection between autophagy and PKA in neuronal signaling, with implications for neurological disease. Great collaboration with @manciaslab.bsky.social!

The EMBO Journal@embojournal.org · 2y ago

AKAP11 recruits PKA holoenzymes to #autophagosomes in a bidirectional functional association, both promoting downstream PKA signaling and increasing AKAP11-PKA complex degradation @robzonculab.bsky.social @ucberkeleyofficial.bsky.social www.embopress.org/doi/full/10....

The Lab Coat Rack 🥼

Happy to announce a new paper on a very promising monomeric red fluorescent protein (mScarlet3-H) from the Wu, Zheng, Piatkevich, and Fu labs. mScarlet3-H is bright, photostable, and physically stable, making it versatile for advanced bioimaging. www.nature.com/articles/s41...

A highly stable monomeric red fluorescent protein for advanced microscopy - Nature Methods

The red fluorescent protein mScarlet3-H is bright, photostable and very robust to high temperature, chaotropic conditions and oxidative environments. mScarlet3-H works well in correlative light and el...

nature.com

Hace 25  años que el IUOPA abrió una ventana a la formación de nuevos investigadores. Desde aquel curso 2000 hasta ahora, más de 400 estudiantes han pasado por el Doctorado o el Máster en Biomedicina y Oncología Molecular de la Universidad de Oviedo.

I am extremely pleased to share our latest work on the efficacy of the NDP52GE variant in combating the accumulation of pathological forms of Tau and which is emerging as a protective factor against #AlzheimerDisease. #autophagy rdcu.be/ehPVj Kudos to Anna who drove this project! « Ad maiora ... »

A variant of the autophagic receptor NDP52 counteracts phospho-TAU accumulation and emerges as a protective factor for Alzheimer’s disease

Cell Death & Disease - A variant of the autophagic receptor NDP52 counteracts phospho-TAU accumulation and emerges as a protective factor for Alzheimer’s disease

rdcu.be