Good Sunday, all. The past week has been amazing for #cancermetabolism and #mitochondrialbiology. Check this curated issue: biomed.news/bims-camemi/... Biomed News #keepreading "The curious paradox is that when I accept myself just as I am, then I can change."-Carl Rogers
Christian Frezza
@frezzalab.bsky.social
I post papers on #cancermetabolism and #mitochondrialbiology. I also post about academia, metal music, and mindfulness. https://www.cecad.uni-koeln.de/research/principal-investigators/prof-dr-christian-frezza/ https://orcid.org/0000-0002-3293-7397
Good morning mitolovers! Another beautiful week of papers in #cancermetabolism and #mitochondrialbiology has passed. Don't miss the curated list, find it here: biomed.news/bims-camemi/... Biomed News #keepreading "The meaning of being alive is just being alive." -Alan Watts
Good Sunday, mitolovers. Last week, again, saw some beautiful papers in the fields of #cancermetabolism and #mitochondrialbiology. Don't miss them, find them here: biomed.news/bims-camemi/... Biomed News #keepreading "If you are lonely when you are alone, you are in bad company."-Jean-Paul Sartre
Good Sunday, all! Don't miss this weekly curated summary of papers in #cancermetabolism and #mitochondrialbiology, it contains wonderful discoveries. Check it here: biomed.news/bims-camemi/... Biomed News #keepreading "You're only as free as your attention is."-Sam Harris
I have noticed low engagement here, in particular for science papers, while a lot of the politics found on X is gradually moving here too. Is this my impression only? I am considering moving completely to LinkedIn.
Good morning, all! The past week has seen some fantastic papers in #cancermetabolism and #mitochondrialbiology. Check them here: biomed.news/bims-camemi/... Biomed News #keepreading "Time, which changes people, does not alter the image we have of them."-Marcel Proust
Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction: Molecular Cell www.cell.com/molecular-ce...
Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction
Lisci et al. present a unified model revealing how cells escape glutamine addiction, a metabolic vulnerability of several cancers. Combining systematic genetic and nutrient screens, they show that bio...
cell.com
Good Sunday, all. There is a wonderful curated selection of papers in #cancermetabolism and #mitochondrialbiology here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading The real truth, that dare not speak itself, is that no one is in control. Absolutely no one. Terence McKenna
Good morning, all! Here is a beautiful selection of papers in #cancermetabolism and #mitochondrialbiology. Don't miss it! biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading "For everything you do, there will be a last time that you do it."-William B. Irvine
Papers are increasingly challenging to navigate, not only because of the sheer volume of data they contain but also because of their structure. This is a delicate point of discussion that we, as a community, should address. I would love hearing your views on this. network.febs.org/posts/thinki...
Thinking Like a Scientist, Part Three: Hypothesis Retrofitting
Scientific papers are more complex than ever, but are we gaining deeper understanding or losing sight of the hypothesis? In this third part of Thinking like a scientist, I reflect on data-driven scien...
network.febs.org
Chrysanthi Moschandrea and I have developed a new conceptual framework for understanding the role of metabolism in cancer, which we term metabolic permissiveness. We are eager to hear your thoughts on this topic. genesdev.cshlp.org/content/earl...
Metabolic permissiveness: how tissue context shapes cancer
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
Good Sunday, all. Here is your weekly selection of papers in #cancermetabolism and #mitochondrialbiology. So many exciting findings!! biomed.news/bims-camemi/... @biomednews.bsky.social Biomed News #keepreading "I am a part of all that I have met."-Alfred Tennyson
Activated ATF6α is a hepatic tumour driver restricting immunosurveillance www.nature.com/articles/s41...
ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression - Nature
The ZFTA–RELA fusion, an oncogene for ependymomas, promotes the production of itaconate, and its dependence on this metabolite represents a new therapeutic target for this cancer.
nature.com
ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression www.nature.com/articles/s41...
ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression - Nature
The ZFTA–RELA fusion, an oncogene for ependymomas, promotes the production of itaconate, and its dependence on this metabolite represents a new therapeutic target for this cancer.
nature.com
Happy Sunday egg-ficionados! Here comes your weekly issue of #cebooc: biomed.news/bims-cebooc/... Highlight: pubmed.ncbi.nlm.nih.gov/41606324/ by @brugueslab.bsky.social Powered by @biomednews.bsky.social
Good Sunday, mitolovers. Here is the weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology, with truly remarkable papers: lnkd.in/e7HDuVuU @biomednews.bsky.social #keepreading "Attention is the rarest and purest form of generosity."-Simone Weil
Good Sunday, all. Here is the weekly curated summary of papers in #cancermetabolsim and #mitochondrialbiology. Don't miss it! lnkd.in/e9QJz9AZ @biomednews.bsky.social #keepreading "Start right now. Take a small step you can call your own. Don't follow someone else's heroics."-David Whyte
Good Sunday, all! Here is the curated weekly collection of papers in #cancermetabolism and #mitochondrialbiology. Don't miss it; find it here: biomed.news/bims-camemi/... Biomed News #keepreading "It's very simple to be happy. But it's very difficult to be simple." - Rabindranath Tagore
Polyamine-dependent metabolic shielding regulates alternative splicing www.nature.com/articles/s41...
Polyamine-dependent metabolic shielding regulates alternative splicing - Nature
Polyamines prevent the action of kinases on acidic phosphorylatable motifs in spliceosomal proteins, thus providing a mechanism for metabolite-mediated regulation of alternative splicing in cells.
nature.com
Metabolic adaptations rewire CD4+ T cells in a subset-specific manner in human critical illness with and without sepsis www.nature.com/articles/s41...
Metabolic adaptations rewire CD4+ T cells in a subset-specific manner in human critical illness with and without sepsis - Nature Immunology
Rathmell and colleagues show that metabolic reprograming of regulatory T cells is associated with severity of critical illness in patients with and without sepsis.
nature.com
Language model-guided anticipation and discovery of mammalian metabolites www.nature.com/articles/s41...
Client Challenge
nature.com
Good Sunday, all. Here is a great summary of last week's papers in #cancermetabolism and #mitochondrialbiology. Don't miss it! Find it here: biomed.news/bims-camemi/... Biomed News #keepreading "Life isn't a dress rehearsal; this is it. It's your job to show up for this moment" Oliver Burkeman
www.nature.com/articles/s41...
Mitochondrial transfer from glia to neurons protects against peripheral neuropathy - Nature
Mitochondria that are transported from satellite glial cells in dorsal root ganglia to peripheral sensory neurons through tunneling nanotube-like structures provide protection against peripheral neuro...
nature.com
www.nature.com/articles/s41...
Mitochondrial transfer from glia to neurons protects against peripheral neuropathy - Nature
Mitochondria that are transported from satellite glial cells in dorsal root ganglia to peripheral sensory neurons through tunneling nanotube-like structures provide protection against peripheral neuro...
nature.com
www.nature.com/articles/s41... congrats to the @mvhlab.bsky.social !!
Nutrient requirements of organ-specific metastasis in breast cancer - Nature
How the complex interplay between multiple nutrients within the microenvironment dictates potential sites of metastatic cancer growth is explored.
nature.com
Good evening. After some hiccups with the server, your curated weekly issue of papers in #cancermetabolism and #mitochondrialbiology is out! biomed.news/bims-camemi/... Biomed News #keepreading The greatest obstacle to living is expectancy, which hangs upon tomorrow and loses today. Seneca
Widely Targeted Metabolomics and Machine Learning Identify Succinate as a Key Metabolite in Sepsis-Associated Encephalopathy: iScience www.cell.com/iscience/ful...
Widely Targeted Metabolomics and Machine Learning Identify Succinate as a Key Metabolite in Sepsis-Associated Encephalopathy
Sepsis-associated encephalopathy (SAE) is a common and serious complication of sepsis that leads to acute brain dysfunction and long-term cognitive impairment. We used widely targeted LC–MS/MS plasma ...
cell.com
www.nature.com/articles/s41...
BATF2 is a glutamine-responsive tumour suppressor required for type-I interferon-dependent anti-tumour immunity - Nature Communications
STING–type-I interferon pathway regulates the immunogenicity of several cancer types, including head and neck squamous cell carcinoma. Here the authors describe that glutamine metabolism in the tumour...
nature.com
Mitochondrial contact site and cristae organizing system promotes modular assembly of cytochrome c oxidase: Cell Reports www.cell.com/cell-reports...
Mitochondrial contact site and cristae organizing system promotes modular assembly of cytochrome c oxidase
Colina-Tenorio et al. show that MICOS interacts with the Cox1 and Cox3 assembly modules and facilitates respiratory complex IV biogenesis. By recruiting assembly factors and the mitochondrial multifun...
cell.com
Uridine depletion impairs CD8⁺ T cell antitumor activity through N-glycosylation: Cell Metabolism www.cell.com/cell-metabol...
Uridine depletion impairs CD8⁺ T cell antitumor activity through N-glycosylation
Xiao et al. reveal that sorting nexin 17 (SNX17) promotes the synthesis of uridine phosphorylase 1 (UPP1) in tumor cells, leading to a decrease in uridine concentration within the tumor microenvironme...
cell.com