Thanks to my alma mater in Peru 🇵🇪 for such a nice note on my team’s work - spoiler alert it is in Spanish 🇪🇸 youtu.be/cuACsGKHYQU?...

#UNMSM #INFORME: SANMARQUINO PRESENTA MÉTODO PARA ESTUDIAR EL COMPORTAMIENTO DEL CORONAVIRUS

YouTube video by RTV San Marcos

youtu.be

It’s not just binding — force matters in antibodies design 🧬. Our #PR in @eurekalert.bsky.social See more: www.eurekalert.org/news-release...

New study shows antibodies need a strong core — not just grip — to fight SARS-CoV-2

An international team led by Dr. Adolfo Poma (IPPT PAN, Poland) shows that antibody effectiveness depends not only on binding strength but also on their stability under mechanical forces. The findings...

eurekalert.org

🚨 Look at our comprehensive review Computational Methods in Physical Virology: A Critical Perspective Across Lengths and Timescales | ChemRxiv chemrxiv.org/doi/full/10....

Our recent work with GōMartini 3 approach made the front cover of @pccp.rsc.org! Curious about the message behind it? Check it out: Cofas-Vargas et al. A comparative nanomechanical study of antibody and nanobody binding to SARS-CoV-2 variants lnkd.in/dX9FvDpT Stay tune more to come!

I am participating of this fantastic @cecamevents.bsky.social in Toulouse 🇫🇷 www.cecam.org/workshop-det.... So If If you are around let’s talk about large conformational changes in biomolecular simulations with GõMartini 3 approach. 📆 My talk is tomorrow afternoon. See you there!

The Frankfurt Institute for Advanced Studies (FIAS) and the newly funded Cluster of Excellence SCALE are seeking several Independent Research Group Leaders to drive theoretical and computational research in molecular and cellular life science. fias.institute/de/das-fias/...

Discussing my personal experiences navigating neurodiversity in academia, and what worked for me to cope better in my latest column for EMBO Reports. Please share with anyone who might find this useful/helpful. You are not alone. www.embopress.org/doi/full/10....

A personal journey through academia as a neurodiverse scientist | EMBO reports

EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

embopress.org

Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social. How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · last yr.

A conserved mechanism of membrane fusion in nuclear pore complex assembly https://www.biorxiv.org/content/10.1101/2025.07.21.665908v1

🚀 New preprint! We present an optimized contact map protocol for GōMartini 3 protein-assembly simulations. 🔹 Uses high-freq contacts from MD 🔹 Cuts contact sets by ~20–30% while keeping stability 🔹 Improves exploration of metastable states (e.g. SARS-CoV-2 spike) Preprint: doi.org/10.1101/2025...

🚨 Preprint! Our work complements affinity studies for antibodies (Ab) design 🔹 Mechano­stability as design criterion for Abs against viral escape. 🔹 Two-chain topology: H chain bears force, L chain reinforces via inter-chain contacts. Great work by @fcofas.bsky.social www.biorxiv.org/cgi/content/...

A Comparative Nanomechanical Study of Antibody and Nanobody Binding to SARS-CoV-2 Variants

The receptor-binding domain of the SARS-CoV-2 spike protein is the principal target of neutralizing antibodies (Abs) and nanobodies (Nbs). Although their thermodynamic binding properties have been ext...

biorxiv.org

Today our team member @fcofas.bsky.social is attending this @cecamevents.bsky.social organised in Sardegna: The Dual Nature of Glycans in Protein-Protein Interactions: Bridging Computational and Experimental Insights. Thanks to @ncn.gov.pl for this great support!

🚨 "Evolution of the SARS-CoV-2 Spike Protein in Utilizing Host Transmembrane Serine Proteases" 🔬 How variants exploit more than just TMPRSS2 to enter cells. Big thanks to @kpyrc.bsky.social team for this partnership 😎. 📄 Read: doi.org/10.1016/j.is... now in @cp-iscience.bsky.social