Dr. Alexandra Tzilivaki from Charité - Universitätsmedizin Berlin is joining #BOARD26 to promote understanding of how animal research and other approaches complement each other. #BOARD #EARA #SCICOMM youtube.com/shorts/sIxL1...

Alexandra Tzilivaki is joining #BOARD26

YouTube video by The European Animal Research Association (EARA)

youtube.com

Fully packed room with literally hundreds of people for our FENS symposium on 3D genome regulation in the brain. This was an amazing lineup of speakers, too, a star after star, and then the dinner was something else 👌 Feeling so privilaged! ❤️ #FENS2026 w @apombo1.bsky.social @boyanbonev.bsky.social

8/9 The cohort of experts providing feedback for model training probably needs to be diverse and balanced. That also means there should be broad agreement on its composition. One possible approach could be to include, for example, all scientists with a PhD, or the whole current peer-reviewer pool.

I looked at this but left it out of the post, because the gender inference tool could only classify 44% of first authors and 31% of last authors. But given this caveat, this is the distribution: First authors: 71% male, 29% female Last authors: 83% male, 17% female

I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review. open.substack.com/pub/blekhman...

My Peer Review of The 1%

I wanted to like QED's new 1% ranking. I don't.

open.substack.com

bioRxiv alert! CoPhasing resolves haplotype-specific 3D chromatin structures from GAM data, revealing extensive structural heterogeneity between human homologous chromosomes and its interplay with histone modifications and gene expression! Thanks to all coauthors! www.biorxiv.org/content/10.6...

The great colleague Rong Fan led a team of experts at Yale, Hopkins, and UCSD to write a review on 3D multi-comics of tissues and tumors. Check it out: www.nature.com/articles/s41...

Join us for the inaugural FASEB Scientific Research Conference on Neuronal Experience-Regulated Transcription, Oct. 5-7, 2026. Abstract Submission Deadline: Monday, August 3, 2026

Join us for the Inaugural Gordon Research Conference on Neural Genetics & Epigenetics. Application deadline 21 June 2026.

Can one map the genome-wide binding (1) and its protein partners (2) simultaneously from the same sample? Yes, one can. with CUT&ID ✂️🪪 Spearheaded — singlehandedly — by @annanordin.bsky.social No need of transgenesis, cloning and overexpression. Check it out, it's fast and its works.

bioRxivpreprint@biorxivpreprint.bsky.social · 8mo ago

CUT&ID for simultaneous profiling of protein-DNA and protein-protein interactions https://www.biorxiv.org/content/10.64898/2025.12.11.693662v1

It's Friday. This means it is time for a new post on #Autism : The Evidence. If you missed last week, I discussed what is TRULY behind the rise in prevalence. Today I am going to talk about what it is not: #VACCINES . They are SAFE and EFFECTIVE, but where did this idea come from?

More new NIH institute and center director positions posted with a closing date of 11/26/25. hr.nih.gov/careers/open... These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ... 1/3

Very excited to share my second postdoc, now out in Science Advances! We used targeted snRNA-seq to profile four major subnuclei of the primate across three species (including humans). 1/13 www.science.org/doi/10.1126/...

Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates

Specialized cell types and links to psychiatric disorders are revealed by genetic mapping of primate amygdala neurons.

science.org

New work from Iva Buljan @ivabuljan.bsky.social in our lab! We mapped how human tissue architecture changes with age using ~25k histology slides from 983 donors. This is the first body-wide atlas of human microanatomy. 📄 Preprint: www.biorxiv.org/content/10.1...

Model organisms as platforms for training scientific minds www.nature.com/articles/s41...

Alejandro Montenegro@aemonten.bsky.social · 10mo ago

PREACH! www.nature.com/articles/s41...

We’re back! Registration is NOW OPEN for the 6th Annual Meeting on Advances in Nuclear Topology & 3D Chromatin Architecture in Cancer. Don’t miss insights from leading experts in the field. Join us online on Nov 25, 2025—register for free: bit.ly/chromatin-2025 #chromatin2025

Vertebrate Genome Evolution. Annual Symposium of the @louisjeantetfdn.bsky.social Foundation in Geneva. Free access on site and on line. Great speakers for a super interesting topic. #SvantePaabo #HenrikKaessmann organisers 🙏 See you there! @biology-unige.bsky.social @genevunige.bsky.social

Passionate about #SystemsBiology and ready to lead your own research group? Join us at the forefront of discovery — apply now to be a #GroupLeader at the NOVA Institute for Medical Systems Biology, in beautiful Lisbon, PT! Appl. by Oct 8: www.nature.com/naturecareer... #ScienceJobs #JobOffer

Great opportunity! Up to 4 Group Leader positions at the NOVA Institute for Medical Systems Biology (NIMSB) in Computational & Experimental Medical Systems Biology 📍 Lisbon ⏳ Apply by Oct 8 🔗 nimsb.unl.pt/wp-content/u... #Job #SciencePositions #JobOffer #GroupLeaders #Innovation #systemsbiology

NIMSB announces Four Independent Group Leader positions #ScienceJobs #AcademicSky

NIMSB announces Four Independent Group Leader positions

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobrxiv.org

3. The paper above looks at the role of "ex ante" peer review process, such as that of research grants, where results are not known at the time of review. The paper below looks at inescapable incentive problems that arise when trying to incentivize both risk and effort.

Rationalizing risk aversion in science: Why incentives to work hard clash with incentives to take risks

Scientific research requires taking risks, so why does much funded scientific research play it safe? This study uses an economic contracting model to argue that this can be explained in part by the no...

journals.plos.org

Very proud of our paper on "scrambling-by-hopping" LADs, which was just published: www.nature.com/articles/s41.... Congrats to Lise Dauban and the rest of the team – this was a real tour-de-force!

New preprint from @apombo1.bsky.social’s lab on gene regulation; insights into super-enhancers and their role in establishing complex regulatory networks of cell-type specific interactions with other enhancers and genes with specialized cellular functions 🧪🧬 www.biorxiv.org/content/10.1...

Specialised super-enhancer networks in stem cells and neurons

Super-enhancers (SEs) are clusters of enhancers with high transcriptional activity that play essential roles in defining cell identity through regulation of nearby genes. SEs preferentially form multi...

biorxiv.org

(1/n) DNA-PAINT imaging inside the nucleus at single antibody resolution using TIRF? Ultrathin sectioning makes it happen! Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org! doi.org/10.1073/pnas... 👇🧵

(3/n) Inspired by work by Eric Betzig, @heilemannlab.bsky.social, @apombo1.bsky.social and others, we adopted Tokuyasu cryosectioning to enable TIRF-based DNA-PAINT imaging throughout fixed HeLa cells without range constraint. We started with the nucleus & Pol II to explore tkPAINT’s potential.

1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler Tons of open slots, invited and selected speakers all get 20 mins ❤️ #EESNucleus

I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms www.nature.com/articles/s41...

Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications

Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...

nature.com

As requested - A Starter Pack of PIs in Biology (or related fields) who are recruiting PHD STUDENTS! If you would like to be added, feel free to ask! go.bsky.app/Bf4DRFm

Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/

Range extender mediates long-distance enhancer activity - Nature

The REX element is associated with long-range enhancer–promoter interactions.

nature.com