Tessera
Folgen

@ayeletperes.bsky.social

4 Posts92 Follower315 Folgt
Corey Watson@cdubsig.bsky.social · 8mo ago

Happy to see this work on IG light chains from @e-engelbrecht1.bsky.social in press www.nature.com/articles/s41... How else will germline variation impact the expressed repertoire? Can't wait to see! Thanks to awesome collabs: @williamlees.bsky.social @guryaari.bsky.social @ayeletperes.bsky.social

Germline polymorphisms in the immunoglobulin kappa and lambda loci underpinning antibody light chain repertoire variability - Nature Communications

Antibody response variability contributes to differential individual responses and disease outcomes. Here authors show that genetic variation to the IG kappa and IG lambda loci is an important determi...

nature.com

@ayeletperes.bsky.social · 9mo ago

New manuscript out in NAR! tinyurl.com/4rrbuesn 🧬 VDJbase and OGRDB now support 3000+ IG/TR samples across human and rhesus macaque with curated AIRR-seq and long-read genomic data. From population analysis to precision annotation. @guryaari.bsky.social @cdubsig.bsky.social @williamlees.bsky.social

The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbase

Abstract. Accurate characterization of adaptive immune receptor repertoires through high-throughput sequencing is critical for understanding immune respons

academic.oup.com

@ayeletperes.bsky.social · 9mo ago

Excited to see our work on IGHC diversity out! Huge shoutout to @uddalok.bsky.social for leading this study. 🧬 The data is now available on VDJbase, our open resource for exploring B and T cell germline variation across populations. 🧑‍🔬 Go and Explore vdjbase.org! #immunogenetics #VDJbase

VDJbase

vdjbase.org

Corey Watson@cdubsig.bsky.social · 9mo ago

Happy to announce the publication of our work exploring under-appreciated genetic diversity in the human IGHC region. Awesome work by @uddalok.bsky.social. So grateful for our amazing co-authors. @williamlees.bsky.social @guryaari.bsky.social @ayeletperes.bsky.social www.cell.com/cell-genomic...